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The apoptosome is a quaternary protein structure formed in the process of apoptosis. It is formed by the release of cytochrome c from the mitochondrion responses to an internal (intrinsic) or external (extrinsic) cell death stimulus. Stimuli can differ from DNA damage or viral infection to developmental signals for instance like those leading to the…
History & Research
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apaf-1 apoptosis cytochrome caspase-9 death complex domain cell cells protein procaspase-9 bcl-2 domains cancer form atp structure proteins card binds
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Apoptosome | is a | quaternary protein structure formed in the process of apoptosis | 0.90 | text |
| Apoptosome | is a | protein complex assembled around the adapter protein Apaf-1 during mitochondria-mediated apoptosis | 0.90 | text |
| human leukemia cells | instance of | Studies explored its role in conditions | 0.80 | text |
| ovarian cancer | instance of | Studies explored its role in conditions | 0.80 | text |
| viral infections | instance of | Studies explored its role in conditions | 0.80 | text |
| Apoptosome | related to Active action | This | 0.60 | section |
| Apoptosome | related to Active action | Caspase-9 | 0.60 | section |
| Apoptosome | related to Active action | Although | 0.60 | section |
| Apoptosome | related to Active action | There | 0.60 | section |
| Apoptosome | related to Active action | The | 0.60 | section |
| Apoptosome | related to Active action | Reidl | 0.60 | section |
| Apoptosome | related to Active action | Salvasen | 0.60 | section |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.