ZBP1

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Map view:

Zoom: 100%

More settings

Connection length 100% Label size 100% Node size 100% Line width 100% Label width 100%

Export map as:

ZBP1 topic overview

The analysis highlights History, Function and role in disease and Overview as prominent areas in the source structure around ZBP1.

Related topics: 43
Source areas: 5
Connected nodes: 48
Extracted relationships: 135
Concept neighborhoods: 23
Bridge connections: 48

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function and role in disease · 18 topics

Overview · 14 topics

History · 6 topics

Structure · 3 topics

Z-DNA and Z-RNA binding · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ZBP1, C20orf183, DAI, DLM-1, DLM1, Z-DNA binding protein 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L4M, 2LNB, 3EYI, 4KA4
Band: 20q13.31 · 2|2 H3
Bgee: granulocyte · buccal mucosa cell · blood · spleen · monocyte
BioGPS: More reference expression data
Chr.: Chromosome 20 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein
Z-DNA
Z-RNA
Pathogen-associated molecular patterns Pathogen-associated molecular pattern
Receptor Interacting Protein Kinase 3 RIPK3
PANoptosis
Programmed cell death
Influenza A virus
NF-κB signalling NF-κB
Gene
Insulin-like growth factor 2
IMP-1 IGF2BP1
CRD-BP
RNA-binding proteins, RBPs RNA-binding protein

History

Structure

Function and role in disease

Cell death
Caspases Caspase
Pattern-recognition receptor(s) (PRRs) Pattern recognition receptor
Damage-associated molecular patterns Damage-associated molecular pattern
Cytokines Cytokine
Cancer
Fibroblasts Fibroblast
Immune checkpoint blockade
AIM2
Francisella novicida
Herpes simplex virus
Coronaviruses Coronavirus
Cytomegalovirus
Vaccinia
Varicella-zoster virus Varicella zoster virus
Zika virus
Candida albicans
Aspergillus fumigatus

Z-DNA and Z-RNA binding

Supercoiling DNA supercoil
Interferon beta Interferon type I

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ZBP1 connects Entity context

The extracted context around ZBP1 shows recurring relationship patterns in the source. For example, ZBP1 → D3, DLM1, DNA, However, IAV, Influenza, It, N-terminus, Once ZBP1, Since DNA, The, Viral, Viral DNA, Virus, Z-DNA, Z-DNA-binding, Z-form RNAs, Zα, Zβ Another extracted example is ZBP1 → appendix, blood, bone marrow cell, buccal mucosa cell, duodenum, gallbladder, granulocyte, intestinal villus, jejunum, lymph node, mesenteric lymph nodes, monocyte, mucous cell of stomach, rectum, spleen, subcutaneous adipose tissue, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Z-DNA and Z-RNA binding · 19

ZBP1 → D3, DLM1, DNA, However, IAV, Influenza, It, N-terminus, Once ZBP1, Since DNA, The, Viral, Viral DNA, Virus, Z-DNA, Z-DNA-binding, Z-form RNAs, Zα, Zβ

Bgee · 17

ZBP1 → appendix, blood, bone marrow cell, buccal mucosa cell, duodenum, gallbladder, granulocyte, intestinal villus, jejunum, lymph node, mesenteric lymph nodes, monocyte, mucous cell of stomach, rectum, spleen, subcutaneous adipose tissue, thymus

RNA expression pattern · 17

Gene ontology · 15

ZBP1 → biological process, cytoplasm, cytosol, DNA binding, double-stranded RNA adenosine deaminase activity, identical protein binding, immune system process, innate immune response, left-handed Z-DNA binding, nucleus, positive regulation of type I interferon production, positive regulation of type I interferon-mediated signaling pathway, protein binding, regulation of type I interferon production, RNA binding

related to Function and role in disease · 15

ZBP1 → CBL0137, Following, IAV, ICB, IFN, In, NLRP3, PANoptosis, PANoptosomes, PRRs, Recent, RIPKs, ZBP1-ADAR1, ZBP1-mediated, ZBP1-PANoptosome

related to Structure · 14

ZBP1 → At, Both Zα, N-terminus, RHIM, RHIM1, RHIM2, SD, The, The C-terminal, Z-NA, Z-nucleic, Z-RNA/DNA, Zα1, Zα2

related to history · 13

ZBP1 → DNA, Experiments, Further, However, It, RHIM, RIPK, RIPK1, RIPK3, This, Z-NA, ZBP1's, Zbp1-deficient

Band · 2

ZBP1 → 20q13.31, 2|2 H3

Chr. · 2

ZBP1 → Chromosome 2 (mouse), Chromosome 20 (human)

End · 2

ZBP1 → 173,060,716 bp, 57,620,576 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein cell human dna death panoptosis z-dna viral infection bp binding immune virus role innate chr band domains iav gene

ZBP1 relationships Subject–Predicate–Object triples

TTTA extracted 135 structured relationships around ZBP1. Examples in this analysis include ZBP1 → Aliases → ZBP1, C20orf183, DAI, DLM-1, DLM1, Z-DNA binding protein 1 and ZBP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L4M, 2LNB, 3EYI, 4KA4. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
ZBP1	Aliases	ZBP1, C20orf183, DAI, DLM-1, DLM1, Z-DNA binding protein 1	1.00	infobox
ZBP1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L4M, 2LNB, 3EYI, 4KA4	1.00	infobox
ZBP1	Band	20q13.31	1.00	infobox
ZBP1	Band	2\|2 H3	1.00	infobox
ZBP1	Bgee	granulocyte	1.00	infobox
ZBP1	Bgee	buccal mucosa cell	1.00	infobox
ZBP1	Bgee	blood	1.00	infobox
ZBP1	Bgee	spleen	1.00	infobox
ZBP1	Bgee	monocyte	1.00	infobox
ZBP1	Bgee	lymph node	1.00	infobox
ZBP1	Bgee	bone marrow cell	1.00	infobox
ZBP1	Bgee	appendix	1.00	infobox
ZBP1	Bgee	rectum	1.00	infobox
ZBP1	Bgee	gallbladder	1.00	infobox
ZBP1	Bgee	mucous cell of stomach	1.00	infobox
ZBP1	Bgee	jejunum	1.00	infobox
ZBP1	Bgee	thymus	1.00	infobox
ZBP1	Bgee	intestinal villus	1.00	infobox
ZBP1	Bgee	duodenum	1.00	infobox
ZBP1	Bgee	subcutaneous adipose tissue	1.00	infobox
ZBP1	Bgee	mesenteric lymph nodes	1.00	infobox
ZBP1	BioGPS	More reference expression data	1.00	infobox
ZBP1	Chr.	Chromosome 20 (human)	1.00	infobox
ZBP1	Chr.	Chromosome 2 (mouse)	1.00	infobox
ZBP1	Databases	NCBI: entry; OMA: entry	1.00	infobox
ZBP1	End	57,620,576 bp	1.00	infobox
ZBP1	End	173,060,716 bp	1.00	infobox
ZBP1	Ensembl	ENSG00000124256	1.00	infobox
ZBP1	Entrez	81030	1.00	infobox
ZBP1	External IDs	OMIM: 606750; MGI: 1927449; GeneCards: ZBP1	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ZBP1 bring nearby vocabulary together. In this analysis, examples include Cell, Virus and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

ZBP1
- Cell
- Virus
- Protein
- Panoptosis
- Infection
- Death
- Dna
- Function
- Gene
- Identified
- Inflammasome
- Influenza
zbp1
- Cell
- Virus
- Protein
- Panoptosis
- Infection
- Death
- Dna
- Function
- Gene
- Identified
- Inflammasome
- Influenza
protein
- Binding
- Proteins
- Z-dna
- Human
- Zbp1
- Function
- Location
- Cell
- Chromosome
- Gene
- Bp
- Chr
pathogen-associated molecular patterns
- Response
- Z-dna
- Cytoplasm
- Function
- Location
- Mouse
- Z-rna
- Band
- Chromosome
- Gene
- Identified
- Interferon
receptor interacting protein kinase 3
- Binding
- Proteins
- Z-dna
- Human
- Zbp1
- Function
- Location
- Cell
- Chromosome
- Gene
- Bp
- Chr
programmed cell death
- Death
- Inflammatory
- Immune
- Panoptosis
- Innate
- Influenza
- Infection
- Iav
- Identified
- Virus
- Zbp1
- Inflammasome
dna virus
- Inflammasome
- Infections
- Cytoplasm
- Sensor
- Viral
- Zbp1
- Interferon
- Domains
- Role
- Response
- Function
- Location
cell death
- Death
- Inflammatory
- Immune
- Panoptosis
- Innate
- Influenza
- Infection
- Iav
- Identified
- Virus
- Zbp1
- Inflammasome

Connections between topic areas Semantic bridges

For ZBP1, one of the stronger structural bridges in this analysis connects ZBP1 with Function and role in disease. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

ZBP1 — Function and role in disease · splits 30 ⟂ 19

ZBP1 — Overview · splits 34 ⟂ 15

ZBP1 — History · splits 42 ⟂ 7

ZBP1 — Structure · splits 45 ⟂ 4

ZBP1 — Z-DNA and Z-RNA binding · splits 46 ⟂ 3

Map overview Semantic statistics

ZBP1

Nodes49

Edges48

Triples135

Avg. degree1.96

Density0.040816

Components1

Source & methodology

TTTA analyzes the structure around ZBP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Function and role in disease & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ZBP1 · EN edition · Analysis: TopicsToTalkAbout