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Z-DNA-binding protein 1 (also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1) is an intracellular protein in mammals that can activate an innate immune pathways to suppress the viral infection. ZENB1 senses left-handed (Z-form) double-helical Z-DNA and Z-RNA, which are pathogen-associated molecular patterns (PAMPs). It…
History, Function and role in disease & Overview
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protein cell human dna death panoptosis z-dna viral infection bp binding immune virus role innate chr band domains iav gene
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ZBP1 | Aliases | ZBP1, C20orf183, DAI, DLM-1, DLM1, Z-DNA binding protein 1 | 1.00 | infobox |
| ZBP1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L4M, 2LNB, 3EYI, 4KA4 | 1.00 | infobox |
| ZBP1 | Band | 20q13.31 | 1.00 | infobox |
| ZBP1 | Band | 2|2 H3 | 1.00 | infobox |
| ZBP1 | Bgee | granulocyte | 1.00 | infobox |
| ZBP1 | Bgee | buccal mucosa cell | 1.00 | infobox |
| ZBP1 | Bgee | blood | 1.00 | infobox |
| ZBP1 | Bgee | spleen | 1.00 | infobox |
| ZBP1 | Bgee | monocyte | 1.00 | infobox |
| ZBP1 | Bgee | lymph node | 1.00 | infobox |
| ZBP1 | Bgee | bone marrow cell | 1.00 | infobox |
| ZBP1 | Bgee | appendix | 1.00 | infobox |
| ZBP1 | Bgee | rectum | 1.00 | infobox |
| ZBP1 | Bgee | gallbladder | 1.00 | infobox |
| ZBP1 | Bgee | mucous cell of stomach | 1.00 | infobox |
| ZBP1 | Bgee | jejunum | 1.00 | infobox |
| ZBP1 | Bgee | thymus | 1.00 | infobox |
| ZBP1 | Bgee | intestinal villus | 1.00 | infobox |
| ZBP1 | Bgee | duodenum | 1.00 | infobox |
| ZBP1 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| ZBP1 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| ZBP1 | BioGPS | More reference expression data | 1.00 | infobox |
| ZBP1 | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| ZBP1 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| ZBP1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ZBP1 | End | 57,620,576 bp | 1.00 | infobox |
| ZBP1 | End | 173,060,716 bp | 1.00 | infobox |
| ZBP1 | Ensembl | ENSG00000124256 | 1.00 | infobox |
| ZBP1 | Entrez | 81030 | 1.00 | infobox |
| ZBP1 | External IDs | OMIM: 606750; MGI: 1927449; GeneCards: ZBP1 | 1.00 | infobox |
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