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Probenecid

Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia.

History & Applications

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Explore the main themes, entities and connections around Probenecid. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
M04AB01 (WHO)
CAS Number
57-66-9 Y
ChEMBL
ChEMBL897 Y
ChemSpider
4742 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Drug interactions

Pharmacology

History

Advanced semantic analysis

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Map overview Semantic statistics

Probenecid

Nodes44
Edges43
Triples55
Avg. degree1.95
Density0.045455
Components1

How this topic connects Entity context

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Probenecid

Top relations

related to Pharmacodynamics · 5
Probenecid → In, Inhibition, OAT, Pannexin, This
related to Pharmacokinetics · 5
Probenecid → Historically, In, OAT, Penicillins, Probenicid
related to history · 4
Probenecid → During World War II, International Olympic Committee's, January, This
has effect · 3
Probenecid → Life-threatening, Mild, Theoretically
related to Drug interactions · 2
Probenecid → In, Some
3D model (JSmol) · 1
Probenecid → Interactive image
AHFS/Drugs.com · 1
Probenecid → Monograph
ATC code · 1
Probenecid → M04AB01 (WHO)
CAS Number · 1
Probenecid → 57-66-9 Y
ChEMBL · 1
Probenecid → ChEMBL897 Y

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

excretion gout used acid drugs urine penicillin uric concentration drug effects use also plasma kidneys interactions hyperuricemia name probalan increase

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Probenecid3D model (JSmol)Interactive image1.00infobox
ProbenecidAHFS/Drugs.comMonograph1.00infobox
ProbenecidATC codeM04AB01 (WHO)1.00infobox
ProbenecidCAS Number57-66-9 Y1.00infobox
ProbenecidChEMBLChEMBL897 Y1.00infobox
ProbenecidChemSpider4742 Y1.00infobox
ProbenecidCompTox Dashboard (EPA)DTXSID90211881.00infobox
ProbenecidDrugBankDB01032 Y1.00infobox
ProbenecidECHA InfoCard100.000.3131.00infobox
ProbenecidElimination half-life2-6 hours (dose: 0.5-1 g)1.00infobox
ProbenecidExcretionkidney (77-88%)1.00infobox
ProbenecidFormulaC13H19NO4S1.00infobox
ProbenecidIUPHAR/BPS43571.00infobox
ProbenecidKEGGD00475 Y1.00infobox
ProbenecidLegal statusIn general: ℞ (Prescription only)1.00infobox
ProbenecidMedlinePlusa6823951.00infobox
ProbenecidMolar mass285.36 g·mol−11.00infobox
ProbenecidProtein binding75-95%1.00infobox
ProbenecidPubChem CID49111.00infobox
ProbenecidRoutes of administrationBy mouth1.00infobox
ProbenecidTrade namesProbalan1.00infobox
ProbenecidUNIIPO572Z79171.00infobox

Related concept clusters Concept neighborhoods

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    Connections between topic areas Semantic bridges

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