Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Baclofen: History, Community, Culture & Applications

Baclofen, sold under the brand name Lioresal among others, is a central nervous system (CNS) depressant and derivative of the inhibitory neurotransmitter, gamma-Aminobutyric acid (GABA). Baclofen is a potent GABAB receptor agonist, antispasmodic, and skeletal muscle relaxant used to treat chronic muscle spasms and muscle spasticity, such as from a spinal…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Baclofen topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Baclofen. 2 topics appear in more than one source area, which can help identify connections that are less obvious in a linear reading.

Related topics
101
Source areas
8
Connected nodes
111
Extracted relationships
82
Concept neighborhoods
33
Bridge connections
111

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 34 topics
Overview · 32 topics
Overdose · 14 topics
Medical uses · 8 topics
Research · 8 topics
History · 3 topics
Pharmacology · 3 topics
Society and culture · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
M03BX01 (WHO)
Bioavailability
Well-absorbed
CAS Number
1134-47-0
ChEBI
CHEBI:2972

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Overdose

Pharmacology

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Baclofen connects Entity context

The extracted context around Baclofen shows recurring relationship patterns in the source. For example, Baclofen → Ciba-Geigy, Drug Administration, FDA, Heinrich Keberle, Historically, In, Intrathecal, It, Its, Swiss, This, US Food Another extracted example is Baclofen → ANSM, Charcot, CMT, Evidence, French, In, It, Marie, Marketing Authorization, Tooth. Use these groups to spot repeated connection types before inspecting the individual relationships.

Baclofen

Top relations

related to history · 12
Baclofen → Ciba-Geigy, Drug Administration, FDA, Heinrich Keberle, Historically, In, Intrathecal, It, Its, Swiss, This, US Food
related to Research · 10
Baclofen → ANSM, Charcot, CMT, Evidence, French, In, It, Marie, Marketing Authorization, Tooth
related to Withdrawal · 6
Baclofen → Abrupt, Acute, Discontinuation, The, Thus, Withdrawal
Legal status · 5
Baclofen → AU: S4 (Prescription only), CA: ℞-only, NZ: Prescription only, UK: POM (Prescription only), US: ℞-only
related to Pharmacodynamics · 5
Baclofen → Agonism, Baclofen's, For, GABAB, GHB
related to Medical uses · 3
Baclofen → Intrathecal, Parkinson's, Use
related to Overdose · 3
Baclofen → Overdose, Reports, Symptoms
related to Pharmacokinetics · 3
Baclofen → Biotransformation, It, The
is a · 2
Baclofen → effective medication for the treatment of severe, potent GABAB receptor agonist
related to Routes of administration · 2
Baclofen → At, Intrathecal

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

use effects alcohol may withdrawal spasticity symptoms used spinal also intrathecal administration drug doses gabab seizures treatment side receptor dizziness

Baclofen relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around Baclofen. Examples in this analysis include Baclofen → 3D model (JSmol) → Interactive image and Baclofen → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Baclofen3D model (JSmol)Interactive image1.00infobox
BaclofenAHFS/Drugs.comMonograph1.00infobox
BaclofenATC codeM03BX01 (WHO)1.00infobox
BaclofenBioavailabilityWell-absorbed1.00infobox
BaclofenCAS Number1134-47-01.00infobox
BaclofenChEBICHEBI:29721.00infobox
BaclofenChEMBLChEMBL7011.00infobox
BaclofenChemSpider21971.00infobox
BaclofenChiralityRacemic mixture1.00infobox
BaclofenCompTox Dashboard (EPA)DTXSID50226411.00infobox
BaclofenDependence liabilityModerate–high1.00infobox
BaclofenDrug classGABAB receptor agonist, antispasmodic1.00infobox
BaclofenDrugBankDB001811.00infobox
BaclofenECHA InfoCard100.013.1701.00infobox
BaclofenElimination half-life2.5–7 hours1.00infobox
BaclofenExcretionKidney (70–80%)1.00infobox
BaclofenFormulaC10H12ClNO21.00infobox
BaclofenIUPHAR/BPS10841.00infobox
BaclofenKEGGD002411.00infobox
BaclofenLegal statusAU: S4 (Prescription only)1.00infobox
BaclofenLegal statusCA: ℞-only1.00infobox
BaclofenLegal statusNZ: Prescription only1.00infobox
BaclofenLegal statusUK: POM (Prescription only)1.00infobox
BaclofenLegal statusUS: ℞-only1.00infobox
BaclofenLicense dataUS DailyMed: Baclofen1.00infobox
BaclofenMedlinePlusa6825301.00infobox
BaclofenMetabolism85% excreted in urine/faeces unchanged. 15% metabolised by deamination1.00infobox
BaclofenMetabolitesβ-(p-chlorophenyl)-4-hydroxybutyric acid (γ-hydroxybaclofen)1.00infobox
BaclofenMolar mass213.66 g·mol−11.00infobox
BaclofenOther namesBaclophen, β-(4-chlorophenyl)-γ-aminobutyric acid, β-(4-chlorophenyl)-GABA1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Baclofen bring nearby vocabulary together. In this analysis, examples include Spinal, Withdrawal and Use. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Baclofen
    • Spinal
    • Withdrawal
    • Use
    • Treatment
    • Used
    • Symptoms
    • Effects
    • Doses
    • Intrathecal
    • Also
    • May
    • Gabab
  • baclofen
    • Spinal
    • Withdrawal
    • Use
    • Treatment
    • Used
    • Symptoms
    • Effects
    • Doses
    • Intrathecal
    • Also
    • May
    • Gabab
  • agonist
    • Gabab
    • Receptor
    • Antispasmodic
    • Treat
    • Also
    • Used
    • Brand
    • Chronic
    • Sedative
    • Spasms
    • Disorder
    • High
  • muscle spasticity
    • Spasms
    • Disorder
    • Spinal
    • Treat
    • Severe
    • Intrathecal
    • Used
    • Oral
    • Spasticity
    • May
    • Symptoms
    • End
  • alcohol use disorder
    • May
    • Associated
    • Disorder
    • Muscle
    • Treat
    • Used
    • Symptoms
    • Withdrawal
    • Also
    • Sedative
    • Use
    • End
  • opioid withdrawal
    • Symptoms
    • Disorder
    • Alcohol
    • Also
    • May
    • High
    • Muscle
    • Baclofen
    • Used
    • Use
    • Acid
    • Agonist
  • benzodiazepine withdrawal
    • Symptoms
    • Disorder
    • Alcohol
    • Also
    • May
    • High
    • Muscle
    • Baclofen
    • Used
    • Use
    • Acid
    • Agonist
  • alcohol withdrawal
    • Symptoms
    • Associated
    • Disorder
    • Also
    • Sedative
    • Used
    • May
    • Treat
    • Alcohol
    • Withdrawal
    • Use
    • High

Connections between topic areas Semantic bridges

For Baclofen, one of the stronger structural bridges in this analysis connects Baclofen with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Baclofen — Adverse effects · splits 77 ⟂ 35
Baclofen — Overview · splits 79 ⟂ 33
Baclofen — Overdose · splits 97 ⟂ 15
Baclofen — Medical uses · splits 103 ⟂ 9
Baclofen — Research · splits 103 ⟂ 9
Baclofen — Pharmacology · splits 108 ⟂ 4
Baclofen — History · splits 108 ⟂ 4

Map overview Semantic statistics

Baclofen

Nodes112
Edges111
Triples82
Avg. degree1.98
Density0.017857
Components1

Source & methodology

TTTA analyzes the structure around Baclofen to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Baclofen · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.