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Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene. TrkB is a receptor for brain-derived neurotrophic factor (BDNF).
The analysis highlights Members, Ligands and Function as prominent areas in the source structure around Tropomyosin receptor kinase B.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Tropomyosin receptor kinase B shows recurring relationship patterns in the source. For example, Tropomyosin receptor kinase B → activation of phospholipase C activity, ATP binding, axon, axon terminus, brain-derived neurotrophic factor binding, brain-derived neurotrophic factor receptor signaling pathway, brain-derived neurotrophic factor-activated receptor activity, cell differentiation, cell projection, cellular response to amino acid stimulus, cellular response to brain-derived neurotrophic factor stimulus, cellular response to nerve growth factor stimulus, central nervous system neuron development, cerebral cortex development, circadian rhythm, cytoplasm, cytosol, dendrite, dendritic spine, early endosome Another extracted example is Tropomyosin receptor kinase B → anterior amygdaloid area, arcuate nucleus, dorsal motor nucleus of vagus nerve, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, Epithelium of choroid plexus, external globus pallidus, internal globus pallidus, lateral septal nucleus, median eminence, optic nerve, pars reticulata, postcentral gyrus, Region I of hippocampus proper, subiculum, substantia nigra, superior frontal gyrus, superior vestibular nucleus, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
trkb bdnf receptor kinase neurotrophic nt-3 tyrosine human bp protein gene factor ntrk2 chr band binding growth nt-4 trkc shown
TTTA extracted 166 structured relationships around Tropomyosin receptor kinase B. Examples in this analysis include Tropomyosin receptor kinase B → 2.7.10.1 → ↗ and Tropomyosin receptor kinase B → Aliases → NTRK2, GP145-TrkB, TRKB, trk-B, neurotrophic receptor tyrosine kinase 2, OBHD, EIEE58. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Tropomyosin receptor kinase B | 2.7.10.1 | ↗ | 1.00 | infobox |
| Tropomyosin receptor kinase B | Aliases | NTRK2, GP145-TrkB, TRKB, trk-B, neurotrophic receptor tyrosine kinase 2, OBHD, EIEE58 | 1.00 | infobox |
| Tropomyosin receptor kinase B | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4AT5, 1HCF, 1WWB, 2MFQ, 4ASZ, 4AT3, 4AT4 | 1.00 | infobox |
| Tropomyosin receptor kinase B | Band | 9q21.33 | 1.00 | infobox |
| Tropomyosin receptor kinase B | Band | 13 B1|13 31.2 cM | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | optic nerve | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | external globus pallidus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | internal globus pallidus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | superior vestibular nucleus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | dorsal motor nucleus of vagus nerve | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | ventral tegmental area | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | postcentral gyrus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | pars reticulata | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | median eminence | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | arcuate nucleus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | dorsomedial hypothalamic nucleus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | lateral septal nucleus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | superior frontal gyrus | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | substantia nigra | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | subiculum | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | anterior amygdaloid area | 1.00 | infobox |
| Tropomyosin receptor kinase B | Bgee | dorsal tegmental nucleus | 1.00 | infobox |
| Tropomyosin receptor kinase B | BioGPS | More reference expression data | 1.00 | infobox |
| Tropomyosin receptor kinase B | Chr. | Chromosome 9 (human) | 1.00 | infobox |
| Tropomyosin receptor kinase B | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| Tropomyosin receptor kinase B | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Tropomyosin receptor kinase B | End | 85,027,070 bp | 1.00 | infobox |
| Tropomyosin receptor kinase B | End | 59,281,784 bp | 1.00 | infobox |
The concept neighborhoods around Tropomyosin receptor kinase B bring nearby vocabulary together. In this analysis, examples include Tyrosine, Receptor and Ntrk2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Tropomyosin receptor kinase B, one of the stronger structural bridges in this analysis connects Tropomyosin receptor kinase B with Ligands. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Tropomyosin receptor kinase B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members, Ligands & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Tropomyosin receptor kinase B · EN edition · Analysis: TopicsToTalkAbout