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Cytoplasmic protein NCK2 (also known as NCK-beta and Grb4) is a protein that in humans is encoded by the NCK2 gene.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around NCK2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around NCK2 shows recurring relationship patterns in the source. For example, NCK2 → actin filament organization, cell migration, cytoplasm, cytoskeletal anchor activity, cytosol, dendritic spine development, endoplasmic reticulum, ephrin receptor signaling pathway, epidermal growth factor receptor signaling pathway, immunological synapse formation, lamellipodium assembly, negative regulation of cell population proliferation, negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation, negative regulation of peptidyl-serine phosphorylation, negative regulation of PERK-mediated unfolded protein response, negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress, phosphotyrosine residue binding, positive regulation of actin filament polymerization, positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, positive regulation of T cell proliferation Another extracted example is NCK2 → cartilage tissue, dentate gyrus of hippocampal formation granule cell, duodenum, ganglionic eminence, gastric mucosa, genital tubercle, gums, hair follicle, lip, olfactory zone of nasal mucosa, parotid gland, primary visual cortex, Region I of hippocampus proper, right kidney, secondary oocyte, spermatid, tail of embryo, thymus, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp protein chr human band chromosome gene location function adaptor mouse nck receptor grb4 external known search 894 274 end
TTTA extracted 117 structured relationships around NCK2. Examples in this analysis include NCK2 → Aliases → NCK2, GRB4, NCKbeta, NCK adaptor protein 2 and NCK2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5S, 1WX6, 1Z3K, 2B86, 2CIA, 2FRW, 2FRY, 2JXB, 4E6R. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NCK2 | Aliases | NCK2, GRB4, NCKbeta, NCK adaptor protein 2 | 1.00 | infobox |
| NCK2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1U5S, 1WX6, 1Z3K, 2B86, 2CIA, 2FRW, 2FRY, 2JXB, 4E6R | 1.00 | infobox |
| NCK2 | Band | 2q12.2 | 1.00 | infobox |
| NCK2 | Band | 1|1 C1.1 | 1.00 | infobox |
| NCK2 | Bgee | hair follicle | 1.00 | infobox |
| NCK2 | Bgee | parotid gland | 1.00 | infobox |
| NCK2 | Bgee | secondary oocyte | 1.00 | infobox |
| NCK2 | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| NCK2 | Bgee | ganglionic eminence | 1.00 | infobox |
| NCK2 | Bgee | cartilage tissue | 1.00 | infobox |
| NCK2 | Bgee | duodenum | 1.00 | infobox |
| NCK2 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| NCK2 | Bgee | gums | 1.00 | infobox |
| NCK2 | Bgee | gastric mucosa | 1.00 | infobox |
| NCK2 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| NCK2 | Bgee | ventricular zone | 1.00 | infobox |
| NCK2 | Bgee | thymus | 1.00 | infobox |
| NCK2 | Bgee | lip | 1.00 | infobox |
| NCK2 | Bgee | tail of embryo | 1.00 | infobox |
| NCK2 | Bgee | yolk sac | 1.00 | infobox |
| NCK2 | Bgee | primary visual cortex | 1.00 | infobox |
| NCK2 | Bgee | spermatid | 1.00 | infobox |
| NCK2 | Bgee | right kidney | 1.00 | infobox |
| NCK2 | Bgee | genital tubercle | 1.00 | infobox |
| NCK2 | BioGPS | n/a | 1.00 | infobox |
| NCK2 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| NCK2 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| NCK2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NCK2 | End | 105,894,274 bp | 1.00 | infobox |
| NCK2 | End | 43,609,675 bp | 1.00 | infobox |
The concept neighborhoods around NCK2 bring nearby vocabulary together. In this analysis, examples include Nck, Gene and Chromosome. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For NCK2, one of the stronger structural bridges in this analysis connects NCK2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around NCK2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — NCK2 · EN edition · Analysis: TopicsToTalkAbout