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HIOC

HIOC is a small-molecule agent which acts as a selective TrkB receptor agonist (active at at least 100 nM; prominent activation at 500 nM). It was derived from N-acetylserotonin (NAS). Relative to NAS, HIOC possesses greater potency and a longer half-life (~30 min or less for NAS in rats, while HIOC is still detectable up to 24 hours after administration…

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Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
None
CAS Number
314054-36-9
ChemSpider
4192105
CompTox Dashboard (EPA)
DTXSID401032115
Formula
C16H19N3O3

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Overview

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Map overview Semantic statistics

HIOC

Nodes16
Edges15
Triples10
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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HIOC

Top relations

3D model (JSmol) · 1
HIOC → Interactive image
ATC code · 1
HIOC → None
CAS Number · 1
HIOC → 314054-36-9
ChemSpider · 1
HIOC → 4192105
CompTox Dashboard (EPA) · 1
HIOC → DTXSID401032115
Formula · 1
HIOC → C16H19N3O3
Molar mass · 1
HIOC → 301.346 g·mol−1
PubChem CID · 1
HIOC → 5012758
UNII · 1
HIOC → JC3KZQ72GW
is a · 1
HIOC → small-molecule agent which acts as a selective TrkB receptor agonist

Important terminology Word statistics

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Important terminology

receptor trkb active activation nas small-molecule agent selective agonist n-acetylserotonin half-life blood-brain-barrier excitotoxicity acts least 100 nm prominent 500 derived

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HIOC3D model (JSmol)Interactive image1.00infobox
HIOCATC codeNone1.00infobox
HIOCCAS Number314054-36-91.00infobox
HIOCChemSpider41921051.00infobox
HIOCCompTox Dashboard (EPA)DTXSID4010321151.00infobox
HIOCFormulaC16H19N3O31.00infobox
HIOCMolar mass301.346 g·mol−11.00infobox
HIOCPubChem CID50127581.00infobox
HIOCUNIIJC3KZQ72GW1.00infobox
HIOCis asmall-molecule agent which acts as a selective TrkB receptor agonist0.90text

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