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Lisuride

Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline family which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth.

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Explore the main themes, entities and connections around Lisuride. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Pharmacology

62 related topics

Chemistry

15 related topics

Society and culture

11 related topics

Overview

29 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
G02CB02 (WHO) N02CA07 (WHO)
Bioavailability
10–20%
CAS Number
18016-80-3 Y
ChEBI
CHEBI:51164 Y

Topics to explore

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Overview

Medical uses

Pharmacology

Chemistry

History

Society and culture

Research

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Map overview Semantic statistics

Lisuride

Nodes136
Edges135
Triples114
Avg. degree1.99
Density0.014706
Components1

How this topic connects Entity context

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Lisuride

Top relations

related to Pharmacodynamics · 28
Lisuride → Accordingly, Alternatively, D1, D2, D3, D4, D5, Due, GPCR, Gq, H1, However, HT1A, HT1B, HT1D, HT2A, HT2B, HT2C, HT5A, It
related to Brand names · 12
Lisuride → Arolac, Cuvalit, Dopagon, Dopergin, Dopergine, Eunal, Lisenil, Lizenil, Lysenyl, Proclacam, Prolacam, Revanil
related to Availability · 9
Lisuride → Egypt, France, Italy, Kuwait, Lebanon, Mexico, New Zealand, Pakistan, United States
related to history · 8
Lisuride → Biochemistry, It, Pharmacy, Prague, Research Institute, Semonský, SPOFA, Zikán
related to Pharmacokinetics · 4
Lisuride → Absorption, Peak, The, This
related to Chemistry · 3
Lisuride → It, LSD, LSD's
related to Medical uses · 3
Lisuride → Evidence, Parkinson's, The
related to Research · 3
Lisuride → As, Parkinson's, Preliminary
Legal status · 2
Lisuride → BR: Class C1 (Other controlled substances), In general: ℞ (Prescription only)
is a · 2
Lisuride → extremely potent serotonin 5-HT1A receptor agonist, partial agonist of the D2

Important terminology Word statistics

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Important terminology

5-ht2a serotonin receptor effects receptors dopamine lsd agonist may parkinson's disease side prolactin doses treatment psychedelic hallucinogenic antagonist high levels

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Lisuride3D model (JSmol)Interactive image1.00infobox
LisurideAHFS/Drugs.comInternational Drug Names1.00infobox
LisurideATC codeG02CB02 (WHO) N02CA07 (WHO)1.00infobox
LisurideBioavailability10–20%1.00infobox
LisurideCAS Number18016-80-3 Y1.00infobox
LisurideChEBICHEBI:51164 Y1.00infobox
LisurideChEMBLChEMBL157138 Y1.00infobox
LisurideChemSpider26847 Y1.00infobox
LisurideCompTox Dashboard (EPA)DTXSID30274075 DTXSID3023217, DTXSID302740751.00infobox
LisurideDrug classSerotonin receptor agonist; Dopamine receptor agonist1.00infobox
LisurideDrugBankDB00589 Y1.00infobox
LisurideECHA InfoCard100.038.0991.00infobox
LisurideElimination half-life2 hours1.00infobox
LisurideExcretionRenal and biliary in equal amounts1.00infobox
LisurideFormulaC20H26N4O1.00infobox
LisurideIUPHAR/BPS431.00infobox
LisurideKEGGD08132 Y1.00infobox
LisurideLegal statusBR: Class C1 (Other controlled substances)1.00infobox
LisurideLegal statusIn general: ℞ (Prescription only)1.00infobox
LisurideMetabolismHepatic1.00infobox
LisurideMetabolitesMore than 15 known1.00infobox
LisurideMolar mass338.455 g·mol−11.00infobox
LisurideOther namesLysuride; Mesorgydin; Methylergol carbamide; 1,1-Diethyl-3-(6-methyl-9,10-didehydroergolin-8α-yl)urea1.00infobox
LisurideProtein binding60–70%1.00infobox
LisuridePubChem CID288641.00infobox
LisurideRoutes of administrationOral Investigational: Subcutaneous implant, transdermal patch1.00infobox
LisurideTrade namesDopergin, others1.00infobox
LisurideUNIIE0QN3D755O1.00infobox
Lisurideis apartial agonist of the D20.90text
Lisurideis aextremely potent serotonin 5-HT1A receptor agonist0.90text

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