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Lisuride: History, Community, Culture & Applications

Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline family which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth.

Language: English [EN]
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Lisuride topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Lisuride.

Related topics
128
Source areas
7
Connected nodes
135
Extracted relationships
114
Concept neighborhoods
39
Bridge connections
135

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 62 topics
Overview · 29 topics
Chemistry · 15 topics
Society and culture · 11 topics
Research · 5 topics
History · 3 topics
Medical uses · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
G02CB02 (WHO) N02CA07 (WHO)
Bioavailability
10–20%
CAS Number
18016-80-3 Y
ChEBI
CHEBI:51164 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Lisuride connects Entity context

The extracted context around Lisuride shows recurring relationship patterns in the source. For example, Lisuride → Accordingly, Alternatively, D1, D2, D3, D4, D5, Due, GPCR, Gq, H1, However, HT1A, HT1B, HT1D, HT2A, HT2B, HT2C, HT5A, It Another extracted example is Lisuride → Arolac, Cuvalit, Dopagon, Dopergin, Dopergine, Eunal, Lisenil, Lizenil, Lysenyl, Proclacam, Prolacam, Revanil. Use these groups to spot repeated connection types before inspecting the individual relationships.

Lisuride

Top relations

related to Pharmacodynamics · 28
Lisuride → Accordingly, Alternatively, D1, D2, D3, D4, D5, Due, GPCR, Gq, H1, However, HT1A, HT1B, HT1D, HT2A, HT2B, HT2C, HT5A, It
related to Brand names · 12
Lisuride → Arolac, Cuvalit, Dopagon, Dopergin, Dopergine, Eunal, Lisenil, Lizenil, Lysenyl, Proclacam, Prolacam, Revanil
related to Availability · 9
Lisuride → Egypt, France, Italy, Kuwait, Lebanon, Mexico, New Zealand, Pakistan, United States
related to history · 8
Lisuride → Biochemistry, It, Pharmacy, Prague, Research Institute, Semonský, SPOFA, Zikán
related to Pharmacokinetics · 4
Lisuride → Absorption, Peak, The, This
related to Chemistry · 3
Lisuride → It, LSD, LSD's
related to Medical uses · 3
Lisuride → Evidence, Parkinson's, The
related to Research · 3
Lisuride → As, Parkinson's, Preliminary
Legal status · 2
Lisuride → BR: Class C1 (Other controlled substances), In general: ℞ (Prescription only)
is a · 2
Lisuride → extremely potent serotonin 5-HT1A receptor agonist, partial agonist of the D2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

5-ht2a serotonin receptor effects receptors dopamine lsd agonist may parkinson's disease side prolactin doses treatment psychedelic hallucinogenic antagonist high levels

Lisuride relationships Subject–Predicate–Object triples

TTTA extracted 114 structured relationships around Lisuride. Examples in this analysis include Lisuride → 3D model (JSmol) → Interactive image and Lisuride → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Lisuride3D model (JSmol)Interactive image1.00infobox
LisurideAHFS/Drugs.comInternational Drug Names1.00infobox
LisurideATC codeG02CB02 (WHO) N02CA07 (WHO)1.00infobox
LisurideBioavailability10–20%1.00infobox
LisurideCAS Number18016-80-3 Y1.00infobox
LisurideChEBICHEBI:51164 Y1.00infobox
LisurideChEMBLChEMBL157138 Y1.00infobox
LisurideChemSpider26847 Y1.00infobox
LisurideCompTox Dashboard (EPA)DTXSID30274075 DTXSID3023217, DTXSID302740751.00infobox
LisurideDrug classSerotonin receptor agonist; Dopamine receptor agonist1.00infobox
LisurideDrugBankDB00589 Y1.00infobox
LisurideECHA InfoCard100.038.0991.00infobox
LisurideElimination half-life2 hours1.00infobox
LisurideExcretionRenal and biliary in equal amounts1.00infobox
LisurideFormulaC20H26N4O1.00infobox
LisurideIUPHAR/BPS431.00infobox
LisurideKEGGD08132 Y1.00infobox
LisurideLegal statusBR: Class C1 (Other controlled substances)1.00infobox
LisurideLegal statusIn general: ℞ (Prescription only)1.00infobox
LisurideMetabolismHepatic1.00infobox
LisurideMetabolitesMore than 15 known1.00infobox
LisurideMolar mass338.455 g·mol−11.00infobox
LisurideOther namesLysuride; Mesorgydin; Methylergol carbamide; 1,1-Diethyl-3-(6-methyl-9,10-didehydroergolin-8α-yl)urea1.00infobox
LisurideProtein binding60–70%1.00infobox
LisuridePubChem CID288641.00infobox
LisurideRoutes of administrationOral Investigational: Subcutaneous implant, transdermal patch1.00infobox
LisurideTrade namesDopergin, others1.00infobox
LisurideUNIIE0QN3D755O1.00infobox
Lisurideis apartial agonist of the D20.90text
Lisurideis aextremely potent serotonin 5-HT1A receptor agonist0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Lisuride bring nearby vocabulary together. In this analysis, examples include Receptor, Serotonin and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Lisuride
    • Receptor
    • Serotonin
    • Effects
    • 5-ht2a
    • Agonist
    • Receptors
    • Due
    • Disease
    • Parkinson's
    • May
    • Dopamine
    • Administration
  • lisuride
    • Receptor
    • Serotonin
    • Effects
    • 5-ht2a
    • Agonist
    • Receptors
    • Due
    • Disease
    • Parkinson's
    • May
    • Dopamine
    • Administration
  • high prolactin levels
    • Prolactin
    • Migraine
    • Levels
    • Treatment
    • Hallucinogenic
    • Parkinson's
    • Doses
    • Names
    • Dopamine
    • Name
    • Urea
    • Activity
  • side effects
    • 5-ht2a
    • Hallucinogenic
    • Side
    • Receptor
    • Doses
    • Serotonin
    • May
    • Psychedelic
    • Nausea
    • Higher
    • Research
    • Lisuride
  • agonist
    • 5-ht1a
    • Receptor
    • 5-ht2a
    • Serotonin
    • Non-hallucinogenic
    • Receptors
    • Antagonist
    • Effects
    • Lisuride
    • Dopamine
    • Names
    • Brand
  • dopamine
    • Serotonin
    • Receptors
    • D2
    • Migraine
    • Prolactin
    • Receptor
    • Parkinson's
    • Lisuride
    • Names
    • 5-ht2a
    • Effects
    • Dopergin
  • partial agonist
    • 5-ht1a
    • Receptor
    • 5-ht2a
    • Serotonin
    • Non-hallucinogenic
    • Receptors
    • Antagonist
    • Effects
    • Lisuride
    • Dopamine
    • Names
    • Brand
  • full or near-full agonist
    • 5-ht1a
    • Receptor
    • 5-ht2a
    • Serotonin
    • Non-hallucinogenic
    • Receptors
    • Antagonist
    • Effects
    • Lisuride
    • Dopamine
    • Names
    • Brand

Connections between topic areas Semantic bridges

For Lisuride, one of the stronger structural bridges in this analysis connects Lisuride with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LisuridePharmacology · splits 73 ⟂ 63
LisurideOverview · splits 106 ⟂ 30
LisurideChemistry · splits 120 ⟂ 16
LisurideSociety and culture · splits 124 ⟂ 12
LisurideResearch · splits 130 ⟂ 6
LisurideMedical uses · splits 132 ⟂ 4
LisurideHistory · splits 132 ⟂ 4

Map overview Semantic statistics

Lisuride

Nodes136
Edges135
Triples114
Avg. degree1.99
Density0.014706
Components1

Source & methodology

TTTA analyzes the structure around Lisuride to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Lisuride · EN edition · Analysis: TopicsToTalkAbout

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