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Tropomyosin receptor kinase C: Members, Role in cancer & Family members

Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase, is a protein that in humans is encoded by the NTRK3 gene.

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Tropomyosin receptor kinase C topic overview

The analysis highlights Members, Role in cancer and Family members as prominent areas in the source structure around Tropomyosin receptor kinase C.

Related topics
55
Source areas
5
Connected nodes
60
Extracted relationships
139
Concept neighborhoods
30
Bridge connections
60

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Role in cancer · 23 topics
Overview · 16 topics
Family members · 11 topics
Function · 3 topics
Role in disease · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.1
Aliases
NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ
Band
15q25.3 · 7 D2|7 44.01 cM
Bgee
Brodmann area 10 · Brodmann area 23 · popliteal artery · tibial arteries · frontal pole
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Family members

Role in disease

Role in cancer

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Tropomyosin receptor kinase C connects Entity context

The extracted context around Tropomyosin receptor kinase C shows recurring relationship patterns in the source. For example, Tropomyosin receptor kinase C → activation of GTPase activity, activation of protein kinase B activity, ATP binding, axon, cell differentiation, cellular response to nerve growth factor stimulus, cellular response to retinoic acid, circadian rhythm, cochlea development, cytoplasm, development of the heart, ephrin receptor signaling pathway, glutamatergic synapse, GPI-linked ephrin receptor activity, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, kinase activity, lens fiber cell differentiation, mechanoreceptor differentiation Another extracted example is Tropomyosin receptor kinase C → aortic valve, ascending aorta, Brodmann area 10, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, frontal pole, lobe of cerebellum, lumbar spinal ganglion, middle frontal gyrus, middle temporal gyrus, olfactory tubercle, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, popliteal artery, right coronary artery, spinal ganglia, subiculum, tibial arteries, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.

Tropomyosin receptor kinase C

Top relations

Gene ontology · 74
Tropomyosin receptor kinase C → activation of GTPase activity, activation of protein kinase B activity, ATP binding, axon, cell differentiation, cellular response to nerve growth factor stimulus, cellular response to retinoic acid, circadian rhythm, cochlea development, cytoplasm, development of the heart, ephrin receptor signaling pathway, glutamatergic synapse, GPI-linked ephrin receptor activity, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, kinase activity, lens fiber cell differentiation, mechanoreceptor differentiation
Bgee · 20
Tropomyosin receptor kinase C → aortic valve, ascending aorta, Brodmann area 10, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, frontal pole, lobe of cerebellum, lumbar spinal ganglion, middle frontal gyrus, middle temporal gyrus, olfactory tubercle, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, popliteal artery, right coronary artery, spinal ganglia, subiculum, tibial arteries, ventral tegmental area
RNA expression pattern · 20
Tropomyosin receptor kinase C → aortic valve, ascending aorta, Brodmann area 10, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, frontal pole, lobe of cerebellum, lumbar spinal ganglion, middle frontal gyrus, middle temporal gyrus, olfactory tubercle, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, popliteal artery, right coronary artery, spinal ganglia, subiculum, tibial arteries, ventral tegmental area
Band · 2
Tropomyosin receptor kinase C → 15q25.3, 7 D2|7 44.01 cM
Chr. · 2
Tropomyosin receptor kinase C → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
Tropomyosin receptor kinase C → 78,738,012 bp, 88,256,791 bp
2.7.10.1 · 1
Tropomyosin receptor kinase C → ↗
Aliases · 1
Tropomyosin receptor kinase C → NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3
Available structures · 1
Tropomyosin receptor kinase C → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ
BioGPS · 1
Tropomyosin receptor kinase C → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

trkc nt-3 receptor kinase ntrk3 tyrosine gene human family trk factor trkb also receptors bp cell neurotrophic shown neurotrophin growth

Tropomyosin receptor kinase C relationships Subject–Predicate–Object triples

TTTA extracted 139 structured relationships around Tropomyosin receptor kinase C. Examples in this analysis include Tropomyosin receptor kinase C → 2.7.10.1 → ↗ and Tropomyosin receptor kinase C → Aliases → NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Tropomyosin receptor kinase C2.7.10.11.00infobox
Tropomyosin receptor kinase CAliasesNTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 31.00infobox
Tropomyosin receptor kinase CAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ1.00infobox
Tropomyosin receptor kinase CBand15q25.31.00infobox
Tropomyosin receptor kinase CBand7 D2|7 44.01 cM1.00infobox
Tropomyosin receptor kinase CBgeeBrodmann area 101.00infobox
Tropomyosin receptor kinase CBgeeBrodmann area 231.00infobox
Tropomyosin receptor kinase CBgeepopliteal artery1.00infobox
Tropomyosin receptor kinase CBgeetibial arteries1.00infobox
Tropomyosin receptor kinase CBgeefrontal pole1.00infobox
Tropomyosin receptor kinase CBgeemiddle temporal gyrus1.00infobox
Tropomyosin receptor kinase CBgeeparaflocculus of cerebellum1.00infobox
Tropomyosin receptor kinase CBgeeright coronary artery1.00infobox
Tropomyosin receptor kinase CBgeespinal ganglia1.00infobox
Tropomyosin receptor kinase CBgeemiddle frontal gyrus1.00infobox
Tropomyosin receptor kinase CBgeeascending aorta1.00infobox
Tropomyosin receptor kinase CBgeesubiculum1.00infobox
Tropomyosin receptor kinase CBgeecerebellar vermis1.00infobox
Tropomyosin receptor kinase CBgeelobe of cerebellum1.00infobox
Tropomyosin receptor kinase CBgeeaortic valve1.00infobox
Tropomyosin receptor kinase CBgeelumbar spinal ganglion1.00infobox
Tropomyosin receptor kinase CBgeedorsomedial hypothalamic nucleus1.00infobox
Tropomyosin receptor kinase CBgeeolfactory tubercle1.00infobox
Tropomyosin receptor kinase CBgeeventral tegmental area1.00infobox
Tropomyosin receptor kinase CBgeeparaventricular nucleus of hypothalamus1.00infobox
Tropomyosin receptor kinase CBioGPSMore reference expression data1.00infobox
Tropomyosin receptor kinase CChr.Chromosome 15 (human)1.00infobox
Tropomyosin receptor kinase CChr.Chromosome 7 (mouse)1.00infobox
Tropomyosin receptor kinase CDatabasesNCBI: entry; OMA: entry1.00infobox
Tropomyosin receptor kinase CEnd88,256,791 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Tropomyosin receptor kinase C bring nearby vocabulary together. In this analysis, examples include Tyrosine, Receptor and Trkc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Tropomyosin receptor kinase C
    • Tyrosine
    • Receptor
    • Trkc
    • Nt-3
    • Receptors
    • Binding
    • Growth
    • Factor
    • Gene
    • Neurotrophic
    • Neurotrophin
    • Ntrk3
  • tropomyosin receptor kinase c
    • Tyrosine
    • Receptor
    • Gene
    • Neurotrophic
    • Trkc
    • Nt-3
    • Protein
    • Receptors
    • Binding
    • Growth
    • Factor
    • Neurotrophin
  • gene
    • Human
    • Chromosome
    • Bp
    • Chr
    • Kinase
    • Neurotrophic
    • Tyrosine
    • Protein
    • Ntrk3
    • Band
    • Function
    • Neurotrophin-3
  • catalytic receptor
    • Tyrosine
    • Trkc
    • Nt-3
    • Receptors
    • Binding
    • Growth
    • Factor
    • Gene
    • Neurotrophic
    • Neurotrophin
    • Ntrk3
    • Also
  • neurotrophin
    • Cell
    • Receptors
    • Neurotrophin-3
    • Receptor
    • Trk
    • Lngfr
    • Proliferation
    • Activity
    • Ntrk3
    • Shown
    • Nt-3
    • Protein
  • nt-3
    • Trkc
    • Receptor
    • Shown
    • Neurotrophin-3
    • Binds
    • Growth
    • Proliferation
    • Factor
    • Neurotrophic
    • Differentiation
    • Neuronal
    • Tyrosine
  • neurotrophin-3
    • Nt-3
    • Receptor
    • Protein
    • Tyrosine
    • Band
    • Binding
    • Chromosome
    • Differentiation
    • Function
    • Neuronal
    • Activated
    • Bp
  • neurotrophic factor
    • Growth
    • Protein
    • Gene
    • Neurotrophic
    • Tyrosine
    • Differentiation
    • Neuronal
    • Neurotrophin-3
    • Receptor
    • Kinase
    • Nt-3
    • Trkc

Connections between topic areas Semantic bridges

For Tropomyosin receptor kinase C, one of the stronger structural bridges in this analysis connects Tropomyosin receptor kinase C with Role in cancer. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Tropomyosin receptor kinase CRole in cancer · splits 37 ⟂ 24
Tropomyosin receptor kinase COverview · splits 44 ⟂ 17
Tropomyosin receptor kinase CFamily members · splits 49 ⟂ 12
Tropomyosin receptor kinase CFunction · splits 57 ⟂ 4
Tropomyosin receptor kinase CRole in disease · splits 58 ⟂ 3

Map overview Semantic statistics

Tropomyosin receptor kinase C

Nodes61
Edges60
Triples139
Avg. degree1.97
Density0.032787
Components1

Source & methodology

TTTA analyzes the structure around Tropomyosin receptor kinase C to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members, Role in cancer & Family members, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Tropomyosin receptor kinase C · EN edition · Analysis: TopicsToTalkAbout

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