Tropomyosin receptor kinase C

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Explore the main themes, entities and connections around Tropomyosin receptor kinase C. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Key facts & relationships

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2.7.10.1: ↗
Aliases: NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ
Band: 15q25.3 · 7 D2|7 44.01 cM
Bgee: Brodmann area 10 · Brodmann area 23 · popliteal artery · tibial arteries · frontal pole
BioGPS: More reference expression data

Topics to explore

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Overview

Protein
Gene
Catalytic receptor
Neurotrophin
NT-3
Neurotrophin-3
Neurotrophic factor
Receptor tyrosine kinases
Kinase
Receptor tyrosine kinase
Ligand
Insulin receptor
IGF-1 receptor Insulin-like growth factor 1 receptor
MuSK protein
Vascular endothelial growth factor
PI3 kinase

Function

PLCG1
PI3K
RAAS Renin–angiotensin system

Family members

Role in disease

Role in cancer

Trk inhibitors Trk inhibitor
Pleiotorpic Pleiotropy
Chemotoxis Chemotaxis
Neuroblastoma
Medulloblastoma
Neuroectodermal brain tumors Neuroectodermal tumor
CpG island CpG-island
Transcription start site (TSS) Transcription start site
HumanMethylation450 Illumina Methylation Assay
Quantitative methylation-specific PCR Methylation specific PCR
Methylight Bisulfite sequencing
Colorectal cancer
Epithelium
Biomarker
SEPT9
DDIT3 DNA damage-inducible transcript 3
FES Feline sarcoma oncogene
FLT3 CD135
SEPT5
SOX1
SOX17
ESCC Esophageal squamous cell carcinoma
Entrectinib

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Map overview Semantic statistics

Nodes61

Edges60

Triples139

Avg. degree1.97

Density0.032787

Components1

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Tropomyosin receptor kinase C

Top relations

Gene ontology · 74

Tropomyosin receptor kinase C → activation of GTPase activity, activation of protein kinase B activity, ATP binding, axon, cell differentiation, cellular response to nerve growth factor stimulus, cellular response to retinoic acid, circadian rhythm, cochlea development, cytoplasm, development of the heart, ephrin receptor signaling pathway, glutamatergic synapse, GPI-linked ephrin receptor activity, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, kinase activity, lens fiber cell differentiation, mechanoreceptor differentiation

Bgee · 20

Tropomyosin receptor kinase C → aortic valve, ascending aorta, Brodmann area 10, Brodmann area 23, cerebellar vermis, dorsomedial hypothalamic nucleus, frontal pole, lobe of cerebellum, lumbar spinal ganglion, middle frontal gyrus, middle temporal gyrus, olfactory tubercle, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, popliteal artery, right coronary artery, spinal ganglia, subiculum, tibial arteries, ventral tegmental area

RNA expression pattern · 20

Band · 2

Tropomyosin receptor kinase C → 15q25.3, 7 D2|7 44.01 cM

Chr. · 2

Tropomyosin receptor kinase C → Chromosome 15 (human), Chromosome 7 (mouse)

End · 2

Tropomyosin receptor kinase C → 78,738,012 bp, 88,256,791 bp

2.7.10.1 · 1

Tropomyosin receptor kinase C → ↗

Aliases · 1

Tropomyosin receptor kinase C → NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3

Available structures · 1

Tropomyosin receptor kinase C → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ

BioGPS · 1

Tropomyosin receptor kinase C → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

trkc nt-3 receptor kinase ntrk3 tyrosine gene human family trk factor trkb also receptors bp cell neurotrophic shown neurotrophin growth

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Tropomyosin receptor kinase C	2.7.10.1	↗	1.00	infobox
Tropomyosin receptor kinase C	Aliases	NTRK3, GP145-TrkC, TRKC, gp145(trkC), neurotrophic receptor tyrosine kinase 3	1.00	infobox
Tropomyosin receptor kinase C	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WWC, 3V5Q, 4YMJ	1.00	infobox
Tropomyosin receptor kinase C	Band	15q25.3	1.00	infobox
Tropomyosin receptor kinase C	Band	7 D2\|7 44.01 cM	1.00	infobox
Tropomyosin receptor kinase C	Bgee	Brodmann area 10	1.00	infobox
Tropomyosin receptor kinase C	Bgee	Brodmann area 23	1.00	infobox
Tropomyosin receptor kinase C	Bgee	popliteal artery	1.00	infobox
Tropomyosin receptor kinase C	Bgee	tibial arteries	1.00	infobox
Tropomyosin receptor kinase C	Bgee	frontal pole	1.00	infobox
Tropomyosin receptor kinase C	Bgee	middle temporal gyrus	1.00	infobox
Tropomyosin receptor kinase C	Bgee	paraflocculus of cerebellum	1.00	infobox
Tropomyosin receptor kinase C	Bgee	right coronary artery	1.00	infobox
Tropomyosin receptor kinase C	Bgee	spinal ganglia	1.00	infobox
Tropomyosin receptor kinase C	Bgee	middle frontal gyrus	1.00	infobox
Tropomyosin receptor kinase C	Bgee	ascending aorta	1.00	infobox
Tropomyosin receptor kinase C	Bgee	subiculum	1.00	infobox
Tropomyosin receptor kinase C	Bgee	cerebellar vermis	1.00	infobox
Tropomyosin receptor kinase C	Bgee	lobe of cerebellum	1.00	infobox
Tropomyosin receptor kinase C	Bgee	aortic valve	1.00	infobox
Tropomyosin receptor kinase C	Bgee	lumbar spinal ganglion	1.00	infobox
Tropomyosin receptor kinase C	Bgee	dorsomedial hypothalamic nucleus	1.00	infobox
Tropomyosin receptor kinase C	Bgee	olfactory tubercle	1.00	infobox
Tropomyosin receptor kinase C	Bgee	ventral tegmental area	1.00	infobox
Tropomyosin receptor kinase C	Bgee	paraventricular nucleus of hypothalamus	1.00	infobox
Tropomyosin receptor kinase C	BioGPS	More reference expression data	1.00	infobox
Tropomyosin receptor kinase C	Chr.	Chromosome 15 (human)	1.00	infobox
Tropomyosin receptor kinase C	Chr.	Chromosome 7 (mouse)	1.00	infobox
Tropomyosin receptor kinase C	Databases	NCBI: entry; OMA: entry	1.00	infobox
Tropomyosin receptor kinase C	End	88,256,791 bp	1.00	infobox

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