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G0 phase

The G0 phase describes a cellular state outside of the replicative cell cycle. Classically, cells were thought to enter G0 primarily due to environmental factors, like nutrient deprivation, that limited the resources necessary for proliferation. Thus it was thought of as a resting phase. G0 is now known to take different forms and occur for multiple…

Characters, Characteristics of quiescent stem cells & Regulation of quiescence

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Characteristics of quiescent stem cells

TranscriptomesHematopoieticHigh-throughputMicroarrayRNA sequencing
18 related topics

Regulation of quiescence

Tumor suppressor genesP53Rb geneProgenitor cellCyclin dependent kinase
25 related topics

Examples of irreversible G0 phase

StromaVasculatureHematopoietic systemEpithelialMetalloproteinases
18 related topics

Mechanism of G0 exit

S phaseHyperphosphorylationCyclin D/Cdk4Cyclin ECyclin C
16 related topics

Topics to explore

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Overview

Diversity of G0 states

Characteristics of quiescent stem cells

Regulation of quiescence

Examples of reversible G0 phase

Examples of irreversible G0 phase

Mechanism of G0 entry

Mechanism of G0 exit

Advanced semantic analysis

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Map overview Semantic statistics

G0 phase

Nodes125
Edges124
Triples34
Avg. degree1.98
Density0.016
Components1

How this topic connects Entity context

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G0 phase

Top relations

related to Cell cycle regulators · 10
G0 phase → CKIs, D1, Finally, For, Functional, G0, In, Lack, Notch, Rb
related to Differentiated muscle · 9
G0 phase → As, Cardiac, During, G0, Importantly, Muscle, Similarly, Skeletal, These
related to Differentiated nerve · 6
G0 phase → DNA, G0, In, Numerous, Outside, These
related to Differentiated bone · 4
G0 phase → G0, Of, Osteocytes, While
related to Mature hepatocytes · 4
G0 phase → G0, Hepatocytes, However, While

Important terminology Word statistics

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Important terminology

cells g0 cell stem quiescent phase rb cycle state rim15 g1 phosphorylation also muscle exit quiescence cyclin differentiated transcription yeast

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
mature hepatocytesinstance ofreversible G0 phases can be found in non-stem cells0.80text
G0 phaserelated to Cell cycle regulatorsFunctional0.60section
G0 phaserelated to Cell cycle regulatorsRb0.60section
G0 phaserelated to Cell cycle regulatorsFor0.60section
G0 phaserelated to Cell cycle regulatorsLack0.60section
G0 phaserelated to Cell cycle regulatorsG00.60section
G0 phaserelated to Cell cycle regulatorsIn0.60section
G0 phaserelated to Cell cycle regulatorsCKIs0.60section
G0 phaserelated to Cell cycle regulatorsD10.60section
G0 phaserelated to Cell cycle regulatorsFinally0.60section
G0 phaserelated to Cell cycle regulatorsNotch0.60section
G0 phaserelated to Differentiated boneOf0.60section

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