E2F4

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Explore the main themes, entities and connections around E2F4. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Structure

DNA binding domain Dimerization Transactivation Asp Glu

5 related topics

Function

E2F Transcription factors Cell cycle

3 related topics

Interactions

Interact Smad3

2 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: E2F4, E2F-4, E2F transcription factor 4
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CF7
Band: 16q22.1 · 8|8 D3
Bgee: pancreatic ductal cell · granulocyte · left uterine tube · anterior pituitary · transverse colon
BioGPS: More reference expression data
Chr.: Chromosome 16 (human) · Chromosome 8 (mouse)

Topics to explore

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Overview

Function

E2F
Transcription factors Transcription factor
Cell cycle

Structure

DNA binding domain
Dimerization Protein dimer
Transactivation
Asp Aspartic acid
Glu Glutamic acid

Interactions

Interact Protein-protein interaction
Smad3

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes17

Edges16

Triples109

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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E2F4

Top relations

Gene ontology · 37

E2F4 → animal organ morphogenesis, blood circulation, cell cycle, cell projection organization, cell volume homeostasis, centriole assembly, cilium assembly, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, epithelial cell development, mitotic cell cycle, motile cilium assembly, multi-ciliated epithelial cell differentiation, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus

Bgee · 19

E2F4 → anterior pituitary, apex of heart, body of stomach, embryo, genital tubercle, granulocyte, left uterine tube, lip, mucosa of transverse colon, muscle of thigh, neural layer of retina, pancreatic ductal cell, right lobe of thyroid gland, tail of embryo, transverse colon, upper lobe of left lung, ventricular zone, yolk sac, zygote

RNA expression pattern · 19

related to External links · 9

E2F4 → E2F4 This, FactorBookE2F4PDBe-KB, Human Transcription, Medicine, Medicine Medical Subject Headings, MeSH, National Library, PDB, United States National Library

Band · 2

E2F4 → 16q22.1, 8|8 D3

Chr. · 2

E2F4 → Chromosome 16 (human), Chromosome 8 (mouse)

End · 2

E2F4 → 106,032,002 bp, 67,198,918 bp

Aliases · 1

E2F4 → E2F4, E2F-4, E2F transcription factor 4

Available structures · 1

E2F4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CF7

BioGPS · 1

E2F4 → More reference expression data

Important terminology Word statistics

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Important terminology

human bp gene transcription protein chr band factor e2f chromosome 16 location proteins mouse dna domain function external family tumor

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
E2F4	Aliases	E2F4, E2F-4, E2F transcription factor 4	1.00	infobox
E2F4	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CF7	1.00	infobox
E2F4	Band	16q22.1	1.00	infobox
E2F4	Band	8\|8 D3	1.00	infobox
E2F4	Bgee	pancreatic ductal cell	1.00	infobox
E2F4	Bgee	granulocyte	1.00	infobox
E2F4	Bgee	left uterine tube	1.00	infobox
E2F4	Bgee	anterior pituitary	1.00	infobox
E2F4	Bgee	transverse colon	1.00	infobox
E2F4	Bgee	mucosa of transverse colon	1.00	infobox
E2F4	Bgee	apex of heart	1.00	infobox
E2F4	Bgee	body of stomach	1.00	infobox
E2F4	Bgee	right lobe of thyroid gland	1.00	infobox
E2F4	Bgee	upper lobe of left lung	1.00	infobox
E2F4	Bgee	tail of embryo	1.00	infobox
E2F4	Bgee	zygote	1.00	infobox
E2F4	Bgee	yolk sac	1.00	infobox
E2F4	Bgee	genital tubercle	1.00	infobox
E2F4	Bgee	ventricular zone	1.00	infobox
E2F4	Bgee	embryo	1.00	infobox
E2F4	Bgee	neural layer of retina	1.00	infobox
E2F4	Bgee	lip	1.00	infobox
E2F4	Bgee	muscle of thigh	1.00	infobox
E2F4	BioGPS	More reference expression data	1.00	infobox
E2F4	Chr.	Chromosome 16 (human)	1.00	infobox
E2F4	Chr.	Chromosome 8 (mouse)	1.00	infobox
E2F4	Databases	NCBI: entry; OMA: entry	1.00	infobox
E2F4	End	67,198,918 bp	1.00	infobox
E2F4	End	106,032,002 bp	1.00	infobox
E2F4	Ensembl	ENSG00000205250	1.00	infobox

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