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MYF5: Expression & Overview

Myogenic factor 5 is a protein that in humans is encoded by the MYF5 gene. It is a protein with a key role in regulating muscle differentiation or myogenesis, specifically the development of skeletal muscle. Myf5 belongs to a family of proteins known as myogenic regulatory factors (MRFs). These basic helix loop helix transcription factors act…

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MYF5 topic overview

The analysis highlights Expression and Overview as prominent areas in the source structure around MYF5.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
129
Concept neighborhoods
9
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
Expression · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MYF5, bHLHc2, myogenic factor 5, EORVA
Band
12q21.31 · 10 D1|10 55.95 cM
Bgee
biceps brachii · muscle of thigh · gastrocnemius muscle · skeletal muscle tissue · deltoid muscle
BioGPS
n/a
Chr.
Chromosome 12 (human) · Chromosome 10 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Expression

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MYF5 connects Entity context

The extracted context around MYF5 shows recurring relationship patterns in the source. For example, MYF5 → camera-type eye development, cartilage condensation, cell differentiation, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, embryonic skeletal system morphogenesis, extracellular matrix organization, multicellular organism development, muscle cell fate commitment, muscle organ development, muscle organ morphogenesis, muscle tissue morphogenesis, nucleoplasm, nucleus, ossification, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, positive regulation of myoblast fusion Another extracted example is MYF5 → biceps brachii, body of tongue, deltoid muscle, exocrine gland, extraocular muscle, gastrocnemius muscle, human fetus, internal carotid artery, male reproductive gland, male urethra, muscle layer of urethra, muscle of thigh, muscle of upper limb, myotome, salivary gland, skeletal muscle tissue, soleus muscle, temporal muscle, tibialis anterior muscle, urethra. Use these groups to spot repeated connection types before inspecting the individual relationships.

MYF5

Top relations

Gene ontology · 37
MYF5 → camera-type eye development, cartilage condensation, cell differentiation, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, embryonic skeletal system morphogenesis, extracellular matrix organization, multicellular organism development, muscle cell fate commitment, muscle organ development, muscle organ morphogenesis, muscle tissue morphogenesis, nucleoplasm, nucleus, ossification, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, positive regulation of myoblast fusion
Bgee · 20
MYF5 → biceps brachii, body of tongue, deltoid muscle, exocrine gland, extraocular muscle, gastrocnemius muscle, human fetus, internal carotid artery, male reproductive gland, male urethra, muscle layer of urethra, muscle of thigh, muscle of upper limb, myotome, salivary gland, skeletal muscle tissue, soleus muscle, temporal muscle, tibialis anterior muscle, urethra
RNA expression pattern · 20
MYF5 → biceps brachii, body of tongue, deltoid muscle, exocrine gland, extraocular muscle, gastrocnemius muscle, human fetus, internal carotid artery, male reproductive gland, male urethra, muscle layer of urethra, muscle of thigh, muscle of upper limb, myotome, salivary gland, skeletal muscle tissue, soleus muscle, temporal muscle, tibialis anterior muscle, urethra
related to Expression · 17
MYF5 → Although, Most, MRF4, MRFs, Myf5-dependent, MyoD, MyoD-dependent, Numerous, Pax3, Some, Sonic, Specifically, Still, The, These, This, While
related to Regulation · 8
MYF5 → After, Although, Following, It, Sonic, Termed, The, This
related to Clinical significance · 5
MYF5 → Although, As, Hypoxia, MRFs, This
Band · 2
MYF5 → 10 D1|10 55.95 cM, 12q21.31
Chr. · 2
MYF5 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
MYF5 → 107,321,995 bp, 80,719,671 bp
is a · 2
MYF5 → first MRF expressed in embryonic myogenesis and is required for adult viability, master regulator of muscle development

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

muscle expression expressed myogenic development skeletal cells factor differentiation bp mrfs gene transcription chr myogenesis human band specifically chromosome enhancer

MYF5 relationships Subject–Predicate–Object triples

TTTA extracted 129 structured relationships around MYF5. Examples in this analysis include MYF5 → Aliases → MYF5, bHLHc2, myogenic factor 5, EORVA and MYF5 → Band → 12q21.31. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MYF5AliasesMYF5, bHLHc2, myogenic factor 5, EORVA1.00infobox
MYF5Band12q21.311.00infobox
MYF5Band10 D1|10 55.95 cM1.00infobox
MYF5Bgeebiceps brachii1.00infobox
MYF5Bgeemuscle of thigh1.00infobox
MYF5Bgeegastrocnemius muscle1.00infobox
MYF5Bgeeskeletal muscle tissue1.00infobox
MYF5Bgeedeltoid muscle1.00infobox
MYF5Bgeetibialis anterior muscle1.00infobox
MYF5Bgeebody of tongue1.00infobox
MYF5Bgeeexocrine gland1.00infobox
MYF5Bgeesalivary gland1.00infobox
MYF5Bgeemale reproductive gland1.00infobox
MYF5Bgeemyotome1.00infobox
MYF5Bgeeurethra1.00infobox
MYF5Bgeemale urethra1.00infobox
MYF5Bgeehuman fetus1.00infobox
MYF5Bgeeextraocular muscle1.00infobox
MYF5Bgeemuscle layer of urethra1.00infobox
MYF5Bgeesoleus muscle1.00infobox
MYF5Bgeemuscle of upper limb1.00infobox
MYF5Bgeeinternal carotid artery1.00infobox
MYF5Bgeetemporal muscle1.00infobox
MYF5BioGPSn/a1.00infobox
MYF5Chr.Chromosome 12 (human)1.00infobox
MYF5Chr.Chromosome 10 (mouse)1.00infobox
MYF5DatabasesNCBI: entry; OMA: entry1.00infobox
MYF5End80,719,671 bp1.00infobox
MYF5End107,321,995 bp1.00infobox
MYF5EnsemblENSG000001110491.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MYF5 bring nearby vocabulary together. In this analysis, examples include Expression, Expressed and Muscle. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MYF5
    • Expression
    • Expressed
    • Muscle
    • Development
    • Myogenesis
    • Myogenic
    • Early
    • Regulation
    • Hypaxial
    • Myod
    • Although
    • Enhancer
  • myf5
    • Expression
    • Expressed
    • Muscle
    • Development
    • Myogenesis
    • Myogenic
    • Early
    • Regulation
    • Hypaxial
    • Myod
    • Although
    • Enhancer
  • myogenic regulatory factors
    • Gene
    • Family
    • Factors
    • Location
    • Myogenic
    • Protein
    • Human
    • Regulation
    • Bp
    • Chr
    • Chromosome
    • Myotome
  • transcription factors
    • Factor
    • Family
    • Myogenic
    • Differentiation
    • Development
    • Mouse
    • Days
    • Expressed
    • Factors
    • Formation
    • Location
    • Protein
  • expression
    • Early
    • Enhancer
    • Myf5
    • Regulation
    • Chromosome
    • Factor
    • Muscle
    • Formation
    • Location
    • Human
    • Part
    • Bp
  • gene
    • Location
    • Human
    • Bp
    • Chr
    • Chromosome
    • Mouse
    • Protein
    • Myogenic
    • Band
    • Regulation
    • Skeletal
    • Early
  • protein
    • Differentiation
    • Mouse
    • Development
    • Location
    • Skeletal
    • Band
    • Early
    • Human
    • Regulation
    • Role
    • Bp
    • Chr
  • myogenesis
    • Although
    • Expressed
    • Protein
    • Early
    • Role
    • Myod
    • Specifically
    • Enhancer
    • Development
    • Skeletal
    • Expression

Connections between topic areas Semantic bridges

For MYF5, one of the stronger structural bridges in this analysis connects MYF5 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MYF5Overview · splits 3 ⟂ 10

Map overview Semantic statistics

MYF5

Nodes13
Edges12
Triples129
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around MYF5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Expression & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MYF5 · EN edition · Analysis: TopicsToTalkAbout

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