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Pericyte: Research, Function & Clinical significance

Pericytes (formerly called Rouget cells) are multi-functional mural cells that adhere to the external surface of the endothelial cells that form the endothelium of capillaries and other microvessels. Pericytes are embedded in the basement membrane of blood capillaries, where they communicate with endothelial cells by means of both direct physical contact…

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Pericyte topic overview

The analysis highlights Research, Function and Clinical significance as prominent areas in the source structure around Pericyte.

Related topics
81
Source areas
5
Connected nodes
86
Extracted relationships
114
Concept neighborhoods
23
Bridge connections
86

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 38 topics
Overview · 15 topics
Clinical significance · 10 topics
Research · 9 topics
Structure · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

FMA
63174
Latin
pericytus
MeSH
D020286
TH
H3.09.02.0.02006

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Pericyte connects Entity context

The extracted context around Pericyte shows recurring relationship patterns in the source. For example, Pericyte → Angiopoietin, Endothelial, GTPases, If, N-cadherin, PDGF, Platelet-derived, S1P, Sphingosine-1-phosphate, TGF, The, There, This, Tie-2 Another extracted example is Pericyte → ALS, Alzheimer's, Animal, Aside, CNS, Furthermore, It, Loss, Parkinson's, Pericytes, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Pericyte

Top relations

related to Endothelial and pericyte interactions · 14
Pericyte → Angiopoietin, Endothelial, GTPases, If, N-cadherin, PDGF, Platelet-derived, S1P, Sphingosine-1-phosphate, TGF, The, There, This, Tie-2
related to Blood–brain barrier · 11
Pericyte → ALS, Alzheimer's, Animal, Aside, CNS, Furthermore, It, Loss, Parkinson's, Pericytes, This
related to Neurodegenerative diseases · 10
Pericyte → Alzheimer's, Alzheimer's-causing, Alzheimer's-like, Immunohistochemical, PDGFB, PDGFRB, Pericyte-deficient, Platelet-derived, Studies, The
related to Angiogenesis and the survival of endothelial cells · 9
Pericyte → Certain, However, If, Microvascular, NG2, Pericytes, Such, These, This
related to Diabetic retinopathy · 9
Pericyte → AGE, AGE's, Because, In, Studies, The, This, While, With
related to Skeletal muscle regeneration and fat formation · 9
Pericyte → BaCl2-induced, CD146, Nes, PDGFRβ, Pericytes, The, Type-1, Type-2, While
related to Structure · 9
Pericyte → At, Both, CNS, Important, In, Many, N-cadherin, Pericytes, These
related to Blood flow · 8
Pericyte → For, In, Increasing, It, Pericytes, Recent, Significantly, This
related to Hemangioma · 7
Pericyte → CD31, During, IV, Takahashi, The, VEGF, Willebrand
related to Hemangiopericytoma · 5
Pericyte → Diagnosis, Hemangiopericytoma, In, It, Treatment

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

pericytes cells endothelial blood also brain barrier capillaries cell flow vascular membrane signaling loss formation types found may communication diabetic

Pericyte relationships Subject–Predicate–Object triples

TTTA extracted 114 structured relationships around Pericyte. Examples in this analysis include Pericyte → FMA → 63174 and Pericyte → Latin → pericytus. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PericyteFMA631741.00infobox
PericyteLatinpericytus1.00infobox
PericyteMeSHD0202861.00infobox
PericyteTHH3.09.02.0.020061.00infobox
Alzheimer'sinstance ofLoss or dysfunction of pericytes is also theorized to contribute to neurodegenerative diseases0.80text
Parkinson'sinstance ofLoss or dysfunction of pericytes is also theorized to contribute to neurodegenerative diseases0.80text
ALS through breakdown of the blood-brain barrier.Blood flowIncreasing evidence suggests that pericytes can regulate blood flow at the capillary levelinstance ofLoss or dysfunction of pericytes is also theorized to contribute to neurodegenerative diseases0.80text
ALS through breakdown of the blood-brain barrierinstance ofLoss or dysfunction of pericytes is also theorized to contribute to neurodegenerative diseases0.80text
hypertensioninstance ofleading to diseases0.80text
tumor formationinstance ofleading to diseases0.80text
or in deficiencyinstance ofleading to diseases0.80text
leading to neurodegenerative diseases.HemangiomaThe clinical phases of hemangioma have physiological differencesinstance ofleading to diseases0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Pericyte bring nearby vocabulary together. In this analysis, examples include Barrier, Leads and Muscle. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Pericyte
    • Barrier
    • Leads
    • Muscle
    • Also
    • Function
    • Studies
    • Communication
    • Pathway
    • Types
    • Flow
    • Loss
    • Cell
  • pericyte
    • Barrier
    • Leads
    • Muscle
    • Also
    • Function
    • Studies
    • Communication
    • Pathway
    • Types
    • Flow
    • Loss
    • Cell
  • mural cells
    • Endothelial
    • Pericytes
    • Signaling
    • Types
    • Capillaries
    • Blood
    • Also
    • Communication
    • Membrane
    • Brain
    • Basement
    • Muscle
  • brain
    • Barrier
    • Formation
    • May
    • Flow
    • Pericytes
    • Function
    • Also
    • Pericyte
    • Growth
    • Cells
    • Loss
    • Capillaries
  • blood–brain barrier
    • Barrier
    • Brain
    • Flow
    • Blood
    • Formation
    • Pericytes
    • Loss
    • Vessels
    • May
    • Pericyte
    • Capillaries
    • Function
  • smooth muscle cells
    • Endothelial
    • Pericytes
    • Pericyte
    • Signaling
    • Types
    • Capillaries
    • Blood
    • Also
    • Communication
    • Membrane
    • Brain
    • Retinopathy
  • mesenchymal stem cells
    • Endothelial
    • Pericytes
    • Signaling
    • Types
    • Capillaries
    • Blood
    • Also
    • Communication
    • Membrane
    • Brain
    • Basement
    • Muscle
  • immune cells
    • Endothelial
    • Pericytes
    • Signaling
    • Types
    • Capillaries
    • Blood
    • Also
    • Communication
    • Membrane
    • Brain
    • Basement
    • Muscle

Connections between topic areas Semantic bridges

For Pericyte, one of the stronger structural bridges in this analysis connects Pericyte with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PericyteFunction · splits 48 ⟂ 39
PericyteOverview · splits 71 ⟂ 16
PericyteClinical significance · splits 76 ⟂ 11
PericyteStructure · splits 77 ⟂ 10
PericyteResearch · splits 77 ⟂ 10

Map overview Semantic statistics

Pericyte

Nodes87
Edges86
Triples114
Avg. degree1.98
Density0.022989
Components1

Source & methodology

TTTA analyzes the structure around Pericyte to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Pericyte · EN edition · Analysis: TopicsToTalkAbout

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