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Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are multiprotein junctional complexes between epithelial cells, sealing and preventing leakage of solutes and water. They also play a critical role maintaining the structure and permeability of endothelial cells. Tight junctions may also serve as leaky…

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FMA
67397
Latin
junctio occludens
MeSH
D019108
TH
H1.00.01.1.02007

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Structure

Functions

Classification

Role in disease

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Map overview Semantic statistics

Tight junction

Nodes50
Edges49
Triples75
Avg. degree1.96
Density0.04
Components1

How this topic connects Entity context

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Tight junction

Top relations

related to Structure · 38
Tight junction → All, Angulin-1/LSR, Angulin-2/ILDR1, Angulin-3/ILDR2, Angulins, As, C-terminus, CAMSAP3, Cingulin, Claudins, Each, In, Investigation, It, JACOP, JAM, JAMs, Junctional Adhesion Molecules, Leukocyte, Leukocytes
related to External links · 12
Tight junction → An Overview, Boston University, Focus, Histology, Histology Learning System, Junctions, Medicine Medical Subject Headings, MeSH, National Library, NetOccludin, NetTight, Zonapse
related to Classification · 5
Tight junction → Epithelia, Examples, For, Other, Tight
related to Functions · 4
Tight junction → At, In, The, Tight
related to Role in disease · 2
Tight junction → HSV, The
see also · 2
Tight junction → CadherinGap, ZonulinAdherens
FMA · 1
Tight junction → 67397
Latin · 1
Tight junction → junctio occludens
MeSH · 1
Tight junction → D019108
TH · 1
Tight junction → H1.00.01.1.02007

Important terminology Word statistics

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Important terminology

tight junctions junction proteins also occludin cells zo-1 role structure claudins angulins transmembrane one paracellular barrier important membrane protein cellular

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Tight junctionFMA673971.00infobox
Tight junctionLatinjunctio occludens1.00infobox
Tight junctionMeSHD0191081.00infobox
Tight junctionTHH1.00.01.1.020071.00infobox
ZO-1 located on the intracellular side of plasma membraneinstance ofThese associate with different peripheral membrane proteins0.80text
which anchor the strands to the actin component of the cytoskeletoninstance ofThese associate with different peripheral membrane proteins0.80text
migrationinstance ofZO-1 has also been implicated in important cellular processes0.80text
and proliferationinstance ofZO-1 has also been implicated in important cellular processes0.80text
material transportinstance ofwhich can be further subdivided into protective barriers and functional barriers serving purposes0.80text
maintenance of osmotic balance.Tight junctions prevent the passage of moleculesinstance ofwhich can be further subdivided into protective barriers and functional barriers serving purposes0.80text
ions through the intercellular space of adjacent cellsinstance ofwhich can be further subdivided into protective barriers and functional barriers serving purposes0.80text
so materials must actually enter the cellsinstance ofwhich can be further subdivided into protective barriers and functional barriers serving purposes0.80text

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    Min side: 3
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