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Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an enzyme that in humans is encoded by the MAPK3 gene.
The analysis highlights Interactions, Function and Clinical significance as prominent areas in the source structure around MAPK3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAPK3 shows recurring relationship patterns in the source. For example, MAPK3 → ageing, animal organ morphogenesis, apoptotic process, arachidonic acid metabolic process, ATP binding, axon guidance, Bergmann glial cell differentiation, BMP signaling pathway, cardiac neural crest cell development involved in heart development, cartilage development, caveola, caveolin-mediated endocytosis, cell cycle, cellular response to amino acid starvation, cellular response to cadmium ion, cellular response to DNA damage stimulus, cellular response to dopamine, cellular response to mechanical stimulus, cellular response to organic substance, cellular response to reactive oxygen species Another extracted example is MAPK3 → amygdala, anterior cingulate cortex, C1 segment, cingulate gyrus, colon, dentate gyrus of hippocampal formation granule cell, duodenum, ectocervix, entorhinal cortex, epithelium of stomach, gastric mucosa, granulocyte, large intestine, lip, mucosa of transverse colon, nucleus accumbens, pyloric antrum, rectum, right frontal lobe, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene human protein kinase chr band erk1 chromosome 16 map mitogen-activated location signaling activity enzyme mouse p44mapk function external
TTTA extracted 183 structured relationships around MAPK3. Examples in this analysis include MAPK3 → 2.7.11.24 → ↗ and MAPK3 → Aliases → MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAPK3 | 2.7.11.24 | ↗ | 1.00 | infobox |
| MAPK3 | Aliases | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3 | 1.00 | infobox |
| MAPK3 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZOQ, 4QTB | 1.00 | infobox |
| MAPK3 | Band | 16p11.2 | 1.00 | infobox |
| MAPK3 | Band | 7 F3|7 69.25 cM | 1.00 | infobox |
| MAPK3 | Bgee | right frontal lobe | 1.00 | infobox |
| MAPK3 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| MAPK3 | Bgee | amygdala | 1.00 | infobox |
| MAPK3 | Bgee | cingulate gyrus | 1.00 | infobox |
| MAPK3 | Bgee | anterior cingulate cortex | 1.00 | infobox |
| MAPK3 | Bgee | gastric mucosa | 1.00 | infobox |
| MAPK3 | Bgee | nucleus accumbens | 1.00 | infobox |
| MAPK3 | Bgee | ectocervix | 1.00 | infobox |
| MAPK3 | Bgee | rectum | 1.00 | infobox |
| MAPK3 | Bgee | C1 segment | 1.00 | infobox |
| MAPK3 | Bgee | granulocyte | 1.00 | infobox |
| MAPK3 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| MAPK3 | Bgee | yolk sac | 1.00 | infobox |
| MAPK3 | Bgee | pyloric antrum | 1.00 | infobox |
| MAPK3 | Bgee | lip | 1.00 | infobox |
| MAPK3 | Bgee | entorhinal cortex | 1.00 | infobox |
| MAPK3 | Bgee | large intestine | 1.00 | infobox |
| MAPK3 | Bgee | colon | 1.00 | infobox |
| MAPK3 | Bgee | epithelium of stomach | 1.00 | infobox |
| MAPK3 | Bgee | duodenum | 1.00 | infobox |
| MAPK3 | BioGPS | More reference expression data | 1.00 | infobox |
| MAPK3 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| MAPK3 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| MAPK3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAPK3 | End | 30,123,506 bp | 1.00 | infobox |
The concept neighborhoods around MAPK3 bring nearby vocabulary together. In this analysis, examples include Gene, Mitogen-activated and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAPK3, one of the stronger structural bridges in this analysis connects MAPK3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAPK3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAPK3 · EN edition · Analysis: TopicsToTalkAbout