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Research this topic
Explore the main themes, entities and connections around MAPK3. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Interactions
10 related topics
Function
Mitogen-activated protein kinaseExtracellular signal-regulated kinasesProliferationDifferentiationCell cycle
7 related topics
Clinical significance
3 related topics
Signaling pathways
2 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 2.7.11.24
- ↗
- Aliases
- MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZOQ, 4QTB
- Band
- 16p11.2 · 7 F3|7 69.25 cM
- Bgee
- right frontal lobe · mucosa of transverse colon · amygdala · cingulate gyrus · anterior cingulate cortex
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Function
- Mitogen-activated protein kinase
- Extracellular signal-regulated kinases
- Proliferation Cell growth
- Differentiation Cellular differentiation
- Cell cycle
- Phosphorylates
- Isoforms
Clinical significance
- IRAK1
- MicroRNAs MicroRNA
- Influenza A
Signaling pathways
Interactions
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.MAPK3
Nodes30
Edges29
Triples183
Avg. degree1.93
Density0.066667
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
MAPK3
Top relations
Gene ontology · 106
MAPK3 → ageing, animal organ morphogenesis, apoptotic process, arachidonic acid metabolic process, ATP binding, axon guidance, Bergmann glial cell differentiation, BMP signaling pathway, cardiac neural crest cell development involved in heart development, cartilage development, caveola, caveolin-mediated endocytosis, cell cycle, cellular response to amino acid starvation, cellular response to cadmium ion, cellular response to DNA damage stimulus, cellular response to dopamine, cellular response to mechanical stimulus, cellular response to organic substance, cellular response to reactive oxygen species
Bgee · 20
MAPK3 → amygdala, anterior cingulate cortex, C1 segment, cingulate gyrus, colon, dentate gyrus of hippocampal formation granule cell, duodenum, ectocervix, entorhinal cortex, epithelium of stomach, gastric mucosa, granulocyte, large intestine, lip, mucosa of transverse colon, nucleus accumbens, pyloric antrum, rectum, right frontal lobe, yolk sac
RNA expression pattern · 20
MAPK3 → amygdala, anterior cingulate cortex, C1 segment, cingulate gyrus, colon, dentate gyrus of hippocampal formation granule cell, duodenum, ectocervix, entorhinal cortex, epithelium of stomach, gastric mucosa, granulocyte, large intestine, lip, mucosa of transverse colon, nucleus accumbens, pyloric antrum, rectum, right frontal lobe, yolk sac
related to Interactions · 7
MAPK3 → DUSP3, DUSP6GTF2I, HDAC4, MAP2K1, MAP2K2, PTPN7, RPS6KA2
Band · 2
MAPK3 → 16p11.2, 7 F3|7 69.25 cM
Chr. · 2
MAPK3 → Chromosome 16 (human), Chromosome 7 (mouse)
End · 2
MAPK3 → 126,364,991 bp, 30,123,506 bp
related to Clinical significance · 2
MAPK3 → IRAK1, It
2.7.11.24 · 1
MAPK3 → ↗
Aliases · 1
MAPK3 → MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
bp gene human protein kinase chr band erk1 chromosome 16 map mitogen-activated location signaling activity enzyme mouse p44mapk function external
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAPK3 | 2.7.11.24 | ↗ | 1.00 | infobox |
| MAPK3 | Aliases | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, mitogen-activated protein kinase 3 | 1.00 | infobox |
| MAPK3 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZOQ, 4QTB | 1.00 | infobox |
| MAPK3 | Band | 16p11.2 | 1.00 | infobox |
| MAPK3 | Band | 7 F3|7 69.25 cM | 1.00 | infobox |
| MAPK3 | Bgee | right frontal lobe | 1.00 | infobox |
| MAPK3 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| MAPK3 | Bgee | amygdala | 1.00 | infobox |
| MAPK3 | Bgee | cingulate gyrus | 1.00 | infobox |
| MAPK3 | Bgee | anterior cingulate cortex | 1.00 | infobox |
| MAPK3 | Bgee | gastric mucosa | 1.00 | infobox |
| MAPK3 | Bgee | nucleus accumbens | 1.00 | infobox |
| MAPK3 | Bgee | ectocervix | 1.00 | infobox |
| MAPK3 | Bgee | rectum | 1.00 | infobox |
| MAPK3 | Bgee | C1 segment | 1.00 | infobox |
| MAPK3 | Bgee | granulocyte | 1.00 | infobox |
| MAPK3 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| MAPK3 | Bgee | yolk sac | 1.00 | infobox |
| MAPK3 | Bgee | pyloric antrum | 1.00 | infobox |
| MAPK3 | Bgee | lip | 1.00 | infobox |
| MAPK3 | Bgee | entorhinal cortex | 1.00 | infobox |
| MAPK3 | Bgee | large intestine | 1.00 | infobox |
| MAPK3 | Bgee | colon | 1.00 | infobox |
| MAPK3 | Bgee | epithelium of stomach | 1.00 | infobox |
| MAPK3 | Bgee | duodenum | 1.00 | infobox |
| MAPK3 | BioGPS | More reference expression data | 1.00 | infobox |
| MAPK3 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| MAPK3 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| MAPK3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAPK3 | End | 30,123,506 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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