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PDGFB

Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene.

Measurement, Clinical significance & Function

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Clinical significance

7 related topics

Function

2 related topics

Overview

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Aliases
PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDG, 3MJG, 4HQU, 4HQX, 4QCI
Band
22q13.1 · 15 E1|15 37.85 cM
Bgee
olfactory bulb · apex of heart · pancreatic ductal cell · right lung · vena cava
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

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Overview

Function

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

PDGFB

Nodes15
Edges14
Triples157
Avg. degree1.87
Density0.133333
Components1

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PDGFB

Top relations

Gene ontology · 92
PDGFB → activation of protein kinase activity, activation of protein kinase B activity, basolateral plasma membrane, cell chemotaxis, cell surface, cellular response to growth factor stimulus, cellular response to mycophenolic acid, chemoattractant activity, collagen binding, collagen-containing extracellular matrix, cytoplasm, development of the heart, embryonic placenta development, endoplasmic reticulum lumen, extracellular matrix, extracellular matrix organization, extracellular region, extracellular space, Golgi lumen, Golgi membrane
Bgee · 18
PDGFB → ankle, apex of heart, digastric muscle, left lung, left lung lobe, left ventricle, olfactory bulb, pancreatic ductal cell, right lobe of thyroid gland, right lung, right ventricle, sternocleidomastoid muscle, subcutaneous adipose tissue, temporal muscle, triceps brachii muscle, upper lobe of left lung, vastus lateralis muscle, vena cava
RNA expression pattern · 18
PDGFB → ankle, apex of heart, digastric muscle, left lung, left lung lobe, left ventricle, olfactory bulb, pancreatic ductal cell, right lobe of thyroid gland, right lung, right ventricle, sternocleidomastoid muscle, subcutaneous adipose tissue, temporal muscle, triceps brachii muscle, upper lobe of left lung, vastus lateralis muscle, vena cava
related to Clinical significance · 6
PDGFB → COL1A-PDGFB, COL1A1, Mutations, Reciprocal, This, Two
Band · 2
PDGFB → 15 E1|15 37.85 cM, 22q13.1
Chr. · 2
PDGFB → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
PDGFB → 39,244,982 bp, 80,014,977 bp
Aliases · 1
PDGFB → PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B
Available structures · 1
PDGFB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDG, 3MJG, 4HQU, 4HQX, 4QCI
BioGPS · 1
PDGFB → More reference expression data

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Important terminology

gene bp growth factor chr human band chromosome 22 platelet-derived protein location mouse subunit function encoded platelet search 244 982

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PDGFBAliasesPDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B1.00infobox
PDGFBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PDG, 3MJG, 4HQU, 4HQX, 4QCI1.00infobox
PDGFBBand22q13.11.00infobox
PDGFBBand15 E1|15 37.85 cM1.00infobox
PDGFBBgeeolfactory bulb1.00infobox
PDGFBBgeeapex of heart1.00infobox
PDGFBBgeepancreatic ductal cell1.00infobox
PDGFBBgeeright lung1.00infobox
PDGFBBgeevena cava1.00infobox
PDGFBBgeesubcutaneous adipose tissue1.00infobox
PDGFBBgeetriceps brachii muscle1.00infobox
PDGFBBgeeleft ventricle1.00infobox
PDGFBBgeeupper lobe of left lung1.00infobox
PDGFBBgeeright lobe of thyroid gland1.00infobox
PDGFBBgeeleft lung1.00infobox
PDGFBBgeedigastric muscle1.00infobox
PDGFBBgeeleft lung lobe1.00infobox
PDGFBBgeevastus lateralis muscle1.00infobox
PDGFBBgeesternocleidomastoid muscle1.00infobox
PDGFBBgeeankle1.00infobox
PDGFBBgeetemporal muscle1.00infobox
PDGFBBgeeright ventricle1.00infobox
PDGFBBioGPSMore reference expression data1.00infobox
PDGFBChr.Chromosome 22 (human)1.00infobox
PDGFBChr.Chromosome 15 (mouse)1.00infobox
PDGFBDatabasesNCBI: entry; OMA: entry1.00infobox
PDGFBEnd39,244,982 bp1.00infobox
PDGFBEnd80,014,977 bp1.00infobox
PDGFBEnsemblENSG000001003111.00infobox
PDGFBEntrez51551.00infobox

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