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GTPase

GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). The GTP binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases.

Functions, Overview & Mechanism

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Overview

Functions

Mechanism

G domain GTPases

Other GTPases

Advanced semantic analysis

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Map overview Semantic statistics

GTPase

Nodes84
Edges83
Triples57
Avg. degree1.98
Density0.02381
Components1

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GTPase

Top relations

related to Mechanism · 20
GTPase → ADP-ribosylation, ARF, GAP, GAPs, GDP, GDP-bound, GTP, GTP-binding, GTP-bound, GTPase-activating, GTPases, However, Hydrolysis, Mg2, Most, Pi, SN2, Some GTPases, The, This
related to Other GTPases · 11
GTPase → AAA, Examples, G-domain-containing, GTP, GTP-hydrolyzing, GTPases, McrB, NACHT, P-loop, There, While
related to SIMIBI class · 10
GTPase → ATPases, BioD, Get3, GTPases, MinD, Much, Named, Several, SIMIBI, SRP
related to G domain GTPases · 6
GTPase → ATP, GTPases, In, KXD, N/T, The
related to External links · 5
GTPase → MBInfo, Medicine Medical Subject Headings, MeSH, National Library, RhoGTPases
related to Functions · 2
GTPase → Examples, GTPases

Important terminology Word statistics

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Important terminology

gtpases proteins protein gtp active gdp signaling many small also domain cell state family hydrolysis class heterotrimeric bound activity distinct

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
those mediating tasteinstance ofincluding transmembrane receptors0.80text
smellinstance ofincluding transmembrane receptors0.80text
vision.Protein biosynthesisinstance ofincluding transmembrane receptors0.80text
GTPaserelated to External linksNational Library0.60section
GTPaserelated to External linksMedicine Medical Subject Headings0.60section
GTPaserelated to External linksMeSH0.60section
GTPaserelated to External linksMBInfo0.60section
GTPaserelated to External linksRhoGTPases0.60section
GTPaserelated to FunctionsGTPases0.60section
GTPaserelated to FunctionsExamples0.60section
GTPaserelated to G domain GTPasesIn0.60section
GTPaserelated to G domain GTPasesGTPases0.60section

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    Min side: 3
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