Gap junction

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Gap junction topic overview

The analysis highlights Structure, Overview and Occurrence and distribution as prominent areas in the source structure around Gap junction.

Related topics: 103
Source areas: 7
Connected nodes: 110
Extracted relationships: 93
Concept neighborhoods: 25
Bridge connections: 110

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 70 topics

Structure · 14 topics

Occurrence and distribution · 7 topics

Properties of connexon pairs · 6 topics

Functions · 4 topics

Discovery · 1 topics

Levels of organization · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

FMA: 67423
MeSH: D017629
TH: H1.00.01.1.02024

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Membrane channels Membrane channel
Cells Cell (biology)
Tight junctions Tight junction
Connexons Connexon
Connexin
Gap junction protein
Tight junction protein ZO-1
Sodium channels Sodium channel
Aquaporin
Next-generation sequencing
Innexin
Vinnexins Vinnexin
Electrical synapse
Action potentials Action potential
Neurons Neuron
Ephaptic pathway Ephaptic coupling
Bystander effect Bystander effect (radiobiology)
Deafness
Atrial fibrillation
Cataracts Cataract
Cardiac muscle
Crystallinity
Aqueous humor Aqueous humour
Neocortex
Hippocampus
Vestibular nucleus
Thalamic reticular nucleus
Locus coeruleus
Inferior olivary nucleus
Trigeminal nerve
Ventral tegmental area
Olfactory bulb
Retina
Spinal cord
Vertebrates Vertebrate
Glial cells Glial cell
Cerebellum
Purkinje neurons Purkinje neuron
Bergmann glial cells Bergmann glial cell
Astrocytes Astrocyte
Oligodendrocytes Oligodendrocyte
Pelizaeus–Merzbacher disease
Multiple sclerosis
CX36 GJD2
CX45 GJC1
Cx26 GJB2
Cx30.2 GJC3
Cx32 GJB1
GJA1
Cx47 GJC2
MiRNAs MiRNA
Connexin 30
Connexin 43
Uterine Uterus
Myometrium
Pregnancy
Fetal development
Labor Childbirth
CX43
Myocytes Muscle cell
Plasma membrane Cell membrane
Ca2+
Macrophages Macrophage
X-ray diffraction
Thin section
Immunocytochemistry
Immunofluorescence
Transmembrane proteins Transmembrane protein
Tubulin
ZO-1 Tight junction protein 1

Structure

Levels of organization

Transmembrane domains Transmembrane domain

Properties of connexon pairs

Conductances Electrical resistance and conductance
PS Siemens (unit)
Second messengers Second messenger
IP 3 Inositol trisphosphate
Daltons Dalton (unit)
Nucleic acids Nucleic acid

Occurrence and distribution

Functions

Signaling cytoplasmic pathways Cell signaling
Glutamate
Nicotinamide adenine dinucleotide
Prostaglandin E2

Discovery

Transmission electron microscopy

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Gap junction connects Entity context

The extracted context around Gap junction shows recurring relationship patterns in the source. For example, Gap junction → Adult, An, Exceptions, Gap, However, Innexins, Of, Pannexins, Since, Sometimes, Techniques, The, Tissues, Trypanosomatidae Another extracted example is Gap junction → DNA, In, Molecules, One, Otherwise, RNA, Tens, The, Two, When. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Occurrence and distribution · 14

Gap junction → Adult, An, Exceptions, Gap, However, Innexins, Of, Pannexins, Since, Sometimes, Techniques, The, Tissues, Trypanosomatidae

related to Levels of organization · 10

Gap junction → DNA, In, Molecules, One, Otherwise, RNA, Tens, The, Two, When

related to Embryonic, organ and tissue development · 8

Gap junction → Conversely, Embryos, Gap, In, It, Refinement, The, While

related to Hemichannel function · 8

Gap junction → At, E2, Hemichannels, In, Nicotinamide, On, This, With

related to Form to function · 7

Gap junction → Gap, Implicit, Later, The, This, Well, When

related to Functions · 7

Gap junction → Adhesive, At, Cx32, Cx36, Cx43, Electrical, Role

related to Properties of connexon pairs · 6

Gap junction → Allows, Ca2, Ensures, Generally, IP, Large

related to Properties of connexons as hemichannels · 6

Gap junction → It, Mechanical, Pore, Some, They, Unpaired

related to Structure · 5

Gap junction → Hetero-hexamers, In, Innexins, Invertebrate, Though

related to Electrical and chemical synapses · 4

Gap junction → Another, Because, By, The

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gap junction junctions connexins cells proteins connexin plaques cell form electrical plaque connexons protein hemichannels connexon membrane channels also intercellular

Gap junction relationships Subject–Predicate–Object triples

TTTA extracted 93 structured relationships around Gap junction. Examples in this analysis include Gap junction → FMA → 67423 and Gap junction → MeSH → D017629. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Gap junction	FMA	67423	1.00	infobox
Gap junction	MeSH	D017629	1.00	infobox
Gap junction	TH	H1.00.01.1.02024	1.00	infobox
confocal microscopy allow more rapid surveys of large areas of tissue	instance of	Techniques	0.80	text
in bone were shown to have cells that were still connected with gap junctions	instance of	Tissues that were traditionally considered to have isolated cells	0.80	text
however tenuously	instance of	Tissues that were traditionally considered to have isolated cells	0.80	text
cancers or the aging process.Since the discovery of innexins	instance of	Sometimes the number of gap junctions are reduced or absent in diseased tissues	0.80	text
pannexins	instance of	Sometimes the number of gap junctions are reduced or absent in diseased tissues	0.80	text
unnexins	instance of	Sometimes the number of gap junctions are reduced or absent in diseased tissues	0.80	text
gaps in our knowledge of intercellular communication are becoming more defined	instance of	Sometimes the number of gap junctions are reduced or absent in diseased tissues	0.80	text
secondary messengers	instance of	which facilitates the transfer of small molecules	0.80	text
metabolites	instance of	which facilitates the transfer of small molecules	0.80	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Gap junction bring nearby vocabulary together. In this analysis, examples include Junction, Junctions and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Gap junction
- Junction
- Junctions
- Cells
- Plaques
- Connexins
- Proteins
- Plaque
- Protein
- Electrical
- Cell
- Channels
- Studies
gap junction
- Junction
- Junctions
- Plaques
- Cells
- Plaque
- Proteins
- Protein
- Connexins
- Electrical
- Two
- Channel
- Cell
membrane channels
- Cell
- Form
- Plaque
- Junction
- Connexons
- Connexins
- Connexin
- Innexins
- Gap
- Molecules
- Shown
- Two
cells
- Junctions
- Gap
- Junction
- Two
- Electrical
- Molecules
- Shown
- May
- Also
- Communication
- Hemichannel
- Later
tight junctions
- Studies
- Connexins
- May
- Known
- Formation
- Also
- Intercellular
- Later
- Plaques
- Found
- Junction
- Cell
connexons
- Two
- Channel
- Membrane
- Hemichannel
- Plaque
- Called
- Form
- Junction
- Hemichannels
- Gap
- Also
- Connexin
connexin
- Proteins
- Protein
- One
- Connexon
- Form
- Junction
- Gap
- Hemichannel
- Called
- Plaques
- Channel
- Membrane
gap junction protein
- Junction
- Junctions
- Plaques
- Cells
- Proteins
- Plaque
- Protein
- Connexins
- Electrical
- One
- Channel
- Two

Connections between topic areas Semantic bridges

For Gap junction, one of the stronger structural bridges in this analysis connects Gap junction with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Gap junction — Overview · splits 40 ⟂ 71

Gap junction — Structure · splits 96 ⟂ 15

Gap junction — Occurrence and distribution · splits 103 ⟂ 8

Gap junction — Properties of connexon pairs · splits 104 ⟂ 7

Gap junction — Functions · splits 106 ⟂ 5

Map overview Semantic statistics

Gap junction

Nodes111

Edges110

Triples93

Avg. degree1.98

Density0.018018

Components1

Source & methodology

TTTA analyzes the structure around Gap junction to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Overview & Occurrence and distribution, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Gap junction · EN edition · Analysis: TopicsToTalkAbout