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Polyol pathway

The polyol pathway is a two-step process that converts glucose to fructose. In this pathway glucose is reduced to sorbitol, which is subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway.

Pathway, Pathology & Overview

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Overview

Pathway

Pathology

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Map overview Semantic statistics

Polyol pathway

Nodes56
Edges55
Triples28
Avg. degree1.96
Density0.035714
Components1

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Polyol pathway

Top relations

related to Pathway · 16
Polyol pathway → A1C, Activation, AGEs, Cells, Hexokinase, However, Myo-inositol, NAD, NADH, NADP, NADPH, RAGE, Sorbitol, The, They, This
related to Pathology · 6
Polyol pathway → In, NADPH, The, This, When, While
related to Endogenous fructose production · 5
Polyol pathway → ATP, Review, This, Under, While
is a · 1
Polyol pathway → two-step process that converts glucose to fructose

Important terminology Word statistics

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Important terminology

pathway sorbitol glucose fructose polyol nadph cells glutathione kidney production activation normal nitric oxide reduced reductase hexokinase retina diabetic nerves

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Polyol pathwayis atwo-step process that converts glucose to fructose0.90text
Polyol pathwayrelated to Endogenous fructose productionWhile0.60section
Polyol pathwayrelated to Endogenous fructose productionUnder0.60section
Polyol pathwayrelated to Endogenous fructose productionReview0.60section
Polyol pathwayrelated to Endogenous fructose productionATP0.60section
Polyol pathwayrelated to Endogenous fructose productionThis0.60section
Polyol pathwayrelated to PathologyWhile0.60section
Polyol pathwayrelated to PathologyThe0.60section
Polyol pathwayrelated to PathologyWhen0.60section
Polyol pathwayrelated to PathologyIn0.60section
Polyol pathwayrelated to PathologyNADPH0.60section
Polyol pathwayrelated to PathologyThis0.60section

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    Min side: 3
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