Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

BCL2L2

Bcl-2-like protein 2 is a 193-amino acid protein that in humans is encoded by the BCL2L2 gene on chromosome 14 (band q11.2-q12). It was originally discovered by Leonie Gibson, Suzanne Cory and colleagues at the Walter and Eliza Hall Institute of Medical Research, who called it Bcl-w.

Clinical significance, Function & Interactions

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around BCL2L2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BCL2L2, BCL-W, BCL2-L-2, BCLW, PPP1R51, BCL2 like 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MK3, 1O0L, 1ZY3, 2Y6W, 4CIM
Band
14q11.2 · 14 C3|14 27.98 cM
Bgee
C1 segment · prefrontal cortex · amygdala · right frontal lobe · postcentral gyrus
BioGPS
More reference expression data
Chr.
Chromosome 14 (human) · Chromosome 14 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

BCL2L2

Nodes36
Edges35
Triples91
Avg. degree1.94
Density0.055556
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

BCL2L2

Top relations

Gene ontology · 25
BCL2L2 → apoptotic process, Bcl-2 family protein complex, BH domain binding, cellular response to amyloid-beta, cellular response to estradiol stimulus, cytoplasm, cytosol, disordered domain specific binding, extrinsic apoptotic signaling pathway in absence of ligand, identical protein binding, intrinsic apoptotic signaling pathway in response to DNA damage, membrane, mitochondrial membranes, mitochondrial outer membrane, mitochondrion, negative regulation of apoptotic process, negative regulation of intrinsic apoptotic signaling pathway, nuclear inclusion body, nucleus, protein binding
Bgee · 20
BCL2L2 → amygdala, Brodmann area 9, C1 segment, cerebellar vermis, cingulate gyrus, habenula, lateral geniculate nucleus, lateral nuclear group of thalamus, lobe of cerebellum, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, muscle layer of sigmoid colon, orbitofrontal cortex, pontine nuclei, postcentral gyrus, prefrontal cortex, right frontal lobe, subiculum, ventral tegmental area
RNA expression pattern · 20
BCL2L2 → amygdala, Brodmann area 9, C1 segment, cerebellar vermis, cingulate gyrus, habenula, lateral geniculate nucleus, lateral nuclear group of thalamus, lobe of cerebellum, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, muscle layer of sigmoid colon, orbitofrontal cortex, pontine nuclei, postcentral gyrus, prefrontal cortex, right frontal lobe, subiculum, ventral tegmental area
Band · 2
BCL2L2 → 14 C3|14 27.98 cM, 14q11.2
Chr. · 2
BCL2L2 → Chromosome 14 (human), Chromosome 14 (mouse)
End · 2
BCL2L2 → 23,311,751 bp, 55,125,691 bp
related to External links · 2
BCL2L2 → Human BCL2L2, UCSC Genome Browser
Aliases · 1
BCL2L2 → BCL2L2, BCL-W, BCL2-L-2, BCLW, PPP1R51, BCL2 like 2
Available structures · 1
BCL2L2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MK3, 1O0L, 1ZY3, 2Y6W, 4CIM
BioGPS · 1
BCL2L2 → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bcl-w band bp human chromosome 14 chr location shown protein mouse family cell function external spermatogenesis search 311 751

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BCL2L2AliasesBCL2L2, BCL-W, BCL2-L-2, BCLW, PPP1R51, BCL2 like 21.00infobox
BCL2L2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MK3, 1O0L, 1ZY3, 2Y6W, 4CIM1.00infobox
BCL2L2Band14q11.21.00infobox
BCL2L2Band14 C3|14 27.98 cM1.00infobox
BCL2L2BgeeC1 segment1.00infobox
BCL2L2Bgeeprefrontal cortex1.00infobox
BCL2L2Bgeeamygdala1.00infobox
BCL2L2Bgeeright frontal lobe1.00infobox
BCL2L2Bgeepostcentral gyrus1.00infobox
BCL2L2Bgeelateral nuclear group of thalamus1.00infobox
BCL2L2BgeeBrodmann area 91.00infobox
BCL2L2Bgeeorbitofrontal cortex1.00infobox
BCL2L2Bgeecingulate gyrus1.00infobox
BCL2L2Bgeemuscle layer of sigmoid colon1.00infobox
BCL2L2Bgeemedial dorsal nucleus1.00infobox
BCL2L2Bgeelobe of cerebellum1.00infobox
BCL2L2Bgeehabenula1.00infobox
BCL2L2Bgeesubiculum1.00infobox
BCL2L2Bgeecerebellar vermis1.00infobox
BCL2L2Bgeemedial geniculate nucleus1.00infobox
BCL2L2Bgeepontine nuclei1.00infobox
BCL2L2Bgeeventral tegmental area1.00infobox
BCL2L2Bgeemedial vestibular nucleus1.00infobox
BCL2L2Bgeelateral geniculate nucleus1.00infobox
BCL2L2BioGPSMore reference expression data1.00infobox
BCL2L2Chr.Chromosome 14 (human)1.00infobox
BCL2L2Chr.Chromosome 14 (mouse)1.00infobox
BCL2L2DatabasesNCBI: entry; OMA: entry1.00infobox
BCL2L2End23,311,751 bp1.00infobox
BCL2L2End55,125,691 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.