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PDPN, i.e., podoplanin, is a small glycoprotein located on the surface membranes of various cell types. While termed PDPN in humans, it is often named: a) OTS-8, gp38, aggrus, antigen PA2.26, or RANDAM-2 (i.e., retinoic acid-induced neuronal differentiated-associated molecule-2) in mice; b) T1α protein or E11 antigen in rats; c) aggrus or gp40 in…
The analysis highlights Tissues distribution, Activation of CLEC-2 and Function and clinical significance as prominent areas in the source structure around PDPN.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PDPN shows recurring relationship patterns in the source. For example, PDPN → actin-mediated cell contraction, amino acid transmembrane transport, amino acid transmembrane transporter activity, amino acid transport, apical plasma membrane, basolateral plasma membrane, cell junction, cell morphogenesis, cell projection, chaperone binding, chemokine binding, cytoplasm, cytoplasmic vesicle, cytosol, filopodium, filopodium membrane, folic acid transmembrane transporter activity, folic acid transport, integral component of membrane, integral component of plasma membrane Another extracted example is PDPN → A13, C-type, Classification, CLEC-2, CLEC1B, CLEC2, CLEC2B, CLEC7A, HIV, Immunoreceptor, Immunoreceptor Tyrosine-based Activation Motif, It, ITAM, PLAG-3/PLAG-4, Polygonaceae, PRO1384, QDED721, S100, S100A13, Signal. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
clec-2 cells studies levels cancer patients mice blood human lung expressed platelets cvtes cell gene activation lymphatic study cancers expression
TTTA extracted 334 structured relationships around PDPN. Examples in this analysis include PDPN → Aliases → PDPN, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A, podoplanin, D2-40 and PDPN → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3WSR, 4YO0. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PDPN | Aliases | PDPN, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A, podoplanin, D2-40 | 1.00 | infobox |
| PDPN | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3WSR, 4YO0 | 1.00 | infobox |
| PDPN | Band | 1p36.21 | 1.00 | infobox |
| PDPN | Band | 4|4 E1 | 1.00 | infobox |
| PDPN | Bgee | tibia | 1.00 | infobox |
| PDPN | Bgee | gonad | 1.00 | infobox |
| PDPN | Bgee | cartilage tissue | 1.00 | infobox |
| PDPN | Bgee | ventricular zone | 1.00 | infobox |
| PDPN | Bgee | germinal epithelium | 1.00 | infobox |
| PDPN | Bgee | retinal pigment epithelium | 1.00 | infobox |
| PDPN | Bgee | secondary oocyte | 1.00 | infobox |
| PDPN | Bgee | ganglionic eminence | 1.00 | infobox |
| PDPN | Bgee | gallbladder | 1.00 | infobox |
| PDPN | Bgee | gastric mucosa | 1.00 | infobox |
| PDPN | Bgee | yolk sac | 1.00 | infobox |
| PDPN | Bgee | lung | 1.00 | infobox |
| PDPN | Bgee | primary oocyte | 1.00 | infobox |
| PDPN | Bgee | zygote | 1.00 | infobox |
| PDPN | Bgee | blastocyst | 1.00 | infobox |
| PDPN | Bgee | urinary bladder | 1.00 | infobox |
| PDPN | Bgee | ovary | 1.00 | infobox |
| PDPN | Bgee | lens | 1.00 | infobox |
| PDPN | BioGPS | More reference expression data | 1.00 | infobox |
| PDPN | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| PDPN | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| PDPN | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PDPN | End | 13,617,957 bp | 1.00 | infobox |
| PDPN | End | 143,026,134 bp | 1.00 | infobox |
| PDPN | Ensembl | ENSG00000162493 | 1.00 | infobox |
| PDPN | Entrez | 10630 | 1.00 | infobox |
The concept neighborhoods around PDPN bring nearby vocabulary together. In this analysis, examples include Cells, Clec-2 and Studies. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PDPN, one of the stronger structural bridges in this analysis connects PDPN with Function and clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PDPN to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Tissues distribution, Activation of CLEC-2 & Function and clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PDPN · EN edition · Analysis: TopicsToTalkAbout