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ACTA2: Standards & Overview

ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of six different actin isoforms and is involved in the contractile…

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ACTA2 topic overview

The analysis highlights Standards and Overview as prominent areas in the source structure around ACTA2.

Related topics
19
Source areas
1
Connected nodes
20
Extracted relationships
82
Concept neighborhoods
13
Bridge connections
20

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 19 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle
Band
10q23.31 · 19|19 C1
Bgee
saphenous vein · tail of epididymis · right coronary artery · popliteal artery · tibial arteries
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ACTA2 connects Entity context

The extracted context around ACTA2 shows recurring relationship patterns in the source. For example, ACTA2 → actin cytoskeleton, ATP binding, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium, glomerular mesangial cell development, lamellipodium, mesenchyme migration, muscle contraction, nucleotide binding, positive regulation of gene expression, positive regulation of transcription, DNA-templated, protein kinase binding, protein-containing complex, regulation of blood pressure, response to virus Another extracted example is ACTA2 → aortic valve, ascending aorta, body of uterus, calvaria, cervix, Descending thoracic aorta, internal carotid artery, iris, migratory enteric neural crest cell, popliteal artery, right coronary artery, saphenous vein, seminal vesicula, tail of epididymis, tibial arteries, tunica media of zone of aorta, umbilical cord, urethra. Use these groups to spot repeated connection types before inspecting the individual relationships.

ACTA2

Top relations

Gene ontology · 22
ACTA2 → actin cytoskeleton, ATP binding, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium, glomerular mesangial cell development, lamellipodium, mesenchyme migration, muscle contraction, nucleotide binding, positive regulation of gene expression, positive regulation of transcription, DNA-templated, protein kinase binding, protein-containing complex, regulation of blood pressure, response to virus
Bgee · 18
ACTA2 → aortic valve, ascending aorta, body of uterus, calvaria, cervix, Descending thoracic aorta, internal carotid artery, iris, migratory enteric neural crest cell, popliteal artery, right coronary artery, saphenous vein, seminal vesicula, tail of epididymis, tibial arteries, tunica media of zone of aorta, umbilical cord, urethra
RNA expression pattern · 18
ACTA2 → aortic valve, ascending aorta, body of uterus, calvaria, cervix, Descending thoracic aorta, internal carotid artery, iris, migratory enteric neural crest cell, popliteal artery, right coronary artery, saphenous vein, seminal vesicula, tail of epididymis, tibial arteries, tunica media of zone of aorta, umbilical cord, urethra
related to External links · 4
ACTA2 → Aortic DissectionsHuman ACTA2, GeneReviews/NIH/NCBI/UW, Thoracic Aortic Aneurysms, UCSC Genome Browser
Band · 2
ACTA2 → 10q23.31, 19|19 C1
Chr. · 2
ACTA2 → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
ACTA2 → 34,232,990 bp, 88,991,339 bp
Aliases · 1
ACTA2 → ACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle
BioGPS · 1
ACTA2 → More reference expression data
Databases · 1
ACTA2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

muscle gene actin smooth bp human chr band aortic contractile chromosome 10 location thoracic α-sma actins protein mouse alpha aliases

ACTA2 relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around ACTA2. Examples in this analysis include ACTA2 → Aliases → ACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle and ACTA2 → Band → 10q23.31. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ACTA2AliasesACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle1.00infobox
ACTA2Band10q23.311.00infobox
ACTA2Band19|19 C11.00infobox
ACTA2Bgeesaphenous vein1.00infobox
ACTA2Bgeetail of epididymis1.00infobox
ACTA2Bgeeright coronary artery1.00infobox
ACTA2Bgeepopliteal artery1.00infobox
ACTA2Bgeetibial arteries1.00infobox
ACTA2Bgeeurethra1.00infobox
ACTA2Bgeeascending aorta1.00infobox
ACTA2Bgeeseminal vesicula1.00infobox
ACTA2Bgeebody of uterus1.00infobox
ACTA2BgeeDescending thoracic aorta1.00infobox
ACTA2Bgeetunica media of zone of aorta1.00infobox
ACTA2Bgeeaortic valve1.00infobox
ACTA2Bgeeiris1.00infobox
ACTA2Bgeeumbilical cord1.00infobox
ACTA2Bgeecervix1.00infobox
ACTA2Bgeecalvaria1.00infobox
ACTA2Bgeemigratory enteric neural crest cell1.00infobox
ACTA2Bgeeinternal carotid artery1.00infobox
ACTA2BioGPSMore reference expression data1.00infobox
ACTA2Chr.Chromosome 10 (human)1.00infobox
ACTA2Chr.Chromosome 19 (mouse)1.00infobox
ACTA2DatabasesNCBI: entry; OMA: entry1.00infobox
ACTA2End88,991,339 bp1.00infobox
ACTA2End34,232,990 bp1.00infobox
ACTA2EnsemblENSG000001077961.00infobox
ACTA2Entrez591.00infobox
ACTA2External IDsOMIM: 102620; MGI: 87909; GeneCards: ACTA21.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ACTA2 bring nearby vocabulary together. In this analysis, examples include Actin, Muscle and Smooth. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ACTA2
    • Actin
    • Muscle
    • Smooth
    • Contractile
    • Gene
    • Aliases
    • Alpha
    • Aorta
    • Associated
    • Protein
    • Α-sma
    • Aortic
  • acta2
    • Actin
    • Muscle
    • Smooth
    • Contractile
    • Gene
    • Aliases
    • Alpha
    • Aorta
    • Associated
    • Protein
    • Α-sma
    • Aortic
  • actin
    • Muscle
    • Smooth
    • Aliases
    • Alpha
    • Aorta
    • Protein
    • Α-sma
    • Aortic
    • Contractile
    • Location
    • Chromosome
    • Human
  • smooth muscle
    • Smooth
    • Gene
    • Aorta
    • Artery
    • Coronary
    • Thoracic
    • Vascular
    • Contractile
    • Location
    • Protein
    • Α-sma
    • Chromosome
  • thoracic aortic disease
    • Vascular
    • Artery
    • Coronary
    • Protein
    • Thoracic
    • Smooth
    • Entry
    • Muscle
    • Ncbi
    • Ucsc
    • Aorta
    • Associated
  • multisystemic smooth muscle dysfunction syndrome
    • Smooth
    • Gene
    • Aorta
    • Artery
    • Coronary
    • Thoracic
    • Vascular
    • Contractile
    • Location
    • Protein
    • Α-sma
    • Chromosome
  • protein
    • Entry
    • Ncbi
    • Ucsc
    • Smooth
    • Aorta
    • Artery
    • Associated
    • Coronary
    • End
    • Mouse
    • Muscle
    • Thoracic
  • coronary artery disease
    • Artery
    • Coronary
    • Thoracic
    • Vascular
    • Entry
    • Ncbi
    • Ucsc
    • Gene
    • Smooth
    • Aorta
    • Associated
    • End

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the ACTA2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

ACTA2

Nodes21
Edges20
Triples82
Avg. degree1.9
Density0.095238
Components1

Source & methodology

TTTA analyzes the structure around ACTA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ACTA2 · EN edition · Analysis: TopicsToTalkAbout

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