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ACTA2

ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of six different actin isoforms and is involved in the contractile…

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Aliases
ACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle
Band
10q23.31 · 19|19 C1
Bgee
saphenous vein · tail of epididymis · right coronary artery · popliteal artery · tibial arteries
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)
Databases
NCBI: entry; OMA: entry

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ACTA2

Nodes21
Edges20
Triples82
Avg. degree1.9
Density0.095238
Components1

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ACTA2

Top relations

Gene ontology · 22
ACTA2 → actin cytoskeleton, ATP binding, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium, glomerular mesangial cell development, lamellipodium, mesenchyme migration, muscle contraction, nucleotide binding, positive regulation of gene expression, positive regulation of transcription, DNA-templated, protein kinase binding, protein-containing complex, regulation of blood pressure, response to virus
Bgee · 18
ACTA2 → aortic valve, ascending aorta, body of uterus, calvaria, cervix, Descending thoracic aorta, internal carotid artery, iris, migratory enteric neural crest cell, popliteal artery, right coronary artery, saphenous vein, seminal vesicula, tail of epididymis, tibial arteries, tunica media of zone of aorta, umbilical cord, urethra
RNA expression pattern · 18
ACTA2 → aortic valve, ascending aorta, body of uterus, calvaria, cervix, Descending thoracic aorta, internal carotid artery, iris, migratory enteric neural crest cell, popliteal artery, right coronary artery, saphenous vein, seminal vesicula, tail of epididymis, tibial arteries, tunica media of zone of aorta, umbilical cord, urethra
related to External links · 4
ACTA2 → Aortic DissectionsHuman ACTA2, GeneReviews/NIH/NCBI/UW, Thoracic Aortic Aneurysms, UCSC Genome Browser
Band · 2
ACTA2 → 10q23.31, 19|19 C1
Chr. · 2
ACTA2 → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
ACTA2 → 34,232,990 bp, 88,991,339 bp
Aliases · 1
ACTA2 → ACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle
BioGPS · 1
ACTA2 → More reference expression data
Databases · 1
ACTA2 → NCBI: entry; OMA: entry

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Important terminology

muscle gene actin smooth bp human chr band aortic contractile chromosome 10 location thoracic α-sma actins protein mouse alpha aliases

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ACTA2AliasesACTA2, AAT6, ACTSA, MYMY5, actin, alpha 2, smooth muscle, aorta, actin alpha 2, smooth muscle1.00infobox
ACTA2Band10q23.311.00infobox
ACTA2Band19|19 C11.00infobox
ACTA2Bgeesaphenous vein1.00infobox
ACTA2Bgeetail of epididymis1.00infobox
ACTA2Bgeeright coronary artery1.00infobox
ACTA2Bgeepopliteal artery1.00infobox
ACTA2Bgeetibial arteries1.00infobox
ACTA2Bgeeurethra1.00infobox
ACTA2Bgeeascending aorta1.00infobox
ACTA2Bgeeseminal vesicula1.00infobox
ACTA2Bgeebody of uterus1.00infobox
ACTA2BgeeDescending thoracic aorta1.00infobox
ACTA2Bgeetunica media of zone of aorta1.00infobox
ACTA2Bgeeaortic valve1.00infobox
ACTA2Bgeeiris1.00infobox
ACTA2Bgeeumbilical cord1.00infobox
ACTA2Bgeecervix1.00infobox
ACTA2Bgeecalvaria1.00infobox
ACTA2Bgeemigratory enteric neural crest cell1.00infobox
ACTA2Bgeeinternal carotid artery1.00infobox
ACTA2BioGPSMore reference expression data1.00infobox
ACTA2Chr.Chromosome 10 (human)1.00infobox
ACTA2Chr.Chromosome 19 (mouse)1.00infobox
ACTA2DatabasesNCBI: entry; OMA: entry1.00infobox
ACTA2End88,991,339 bp1.00infobox
ACTA2End34,232,990 bp1.00infobox
ACTA2EnsemblENSG000001077961.00infobox
ACTA2Entrez591.00infobox
ACTA2External IDsOMIM: 102620; MGI: 87909; GeneCards: ACTA21.00infobox

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