CLEC7A

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CLEC7A topic overview

The analysis highlights Art and Regions as prominent areas in the source structure around CLEC7A.

Related topics: 53
Source areas: 3
Connected nodes: 56
Extracted relationships: 144
Concept neighborhoods: 14
Bridge connections: 56

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 41 topics

Overview · 8 topics

Structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1, CD369, SCARE2, C-type lectin domain family 7 member A, C-type lectin domain containing 7A
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BPD, 2BPE, 2BPH, 2CL8
Band: 12p13.2 · 6|6 F3
Bgee: monocyte · granulocyte · blood · buccal mucosa cell · periodontal fiber
BioGPS: More reference expression data
Chr.: Chromosome 12 (human) · Chromosome 6 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein
Gene
Immunoreceptor tyrosine-based activation motif
Glucans
Dendritic cells Dendritic cell
Monocytes Monocyte
Macrophages Macrophage
B cells B cell

Structure

Function

C-type lectin receptors C-type lectin receptor
Pattern recognition receptors
Fungal cell walls Fungal cell wall
T-cells T-cell
Mycobacteria
Tyrosine phosphorylation
Src family kinases Src family kinase
Syk
PKC-δ PRKCD
CARD9
BCL10
MALT1
CARD-CC CARD-CC family
TRAF6
NF-κB
Cytokines Cytokine
Chemokines Chemokine
TNF
IL-23 Interleukin 23
IL-6 Interleukin 6
IL-2 Interleukin 2
Respiratory burst
Arachidonic acid
Phagocytosis
Saccharomyces
Candida Candida (fungus)
Pneumocystis
Coccidioides
Penicillium
Hypochlorite
CXCL2
IL-1β
IL-1α
CCL3
GM-CSF
G-CSF
Th17
Histoplasma capsulatum
Α-glucan
CD4+ CD4+ T cell
CD8+ T cells CD8+ T cell

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CLEC7A connects Entity context

The extracted context around CLEC7A shows recurring relationship patterns in the source. For example, CLEC7A → carbohydrate binding, carbohydrate mediated signaling, cell recognition, cytoplasm, defense response to protozoan, immune system process, inflammatory response, innate immune response, integral component of membrane, intracellular membrane-bounded organelle, membrane, metal ion binding, MHC protein binding, nucleoplasm, pattern recognition receptor activity, pattern recognition receptor signaling pathway, phagocytosis, recognition, plasma membrane, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cytokine production involved in inflammatory response Another extracted example is CLEC7A → As, BCL10, CARD-CC/BCL10/MALT1, CARD9, CBM, Dimerization, IL-2, IL-23, IL-6, ITAM-like, Ligand, MALT1, NF-κB, Other, PKC-δ, Src, Syk, T-cells, The C-type, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 26

CLEC7A → carbohydrate binding, carbohydrate mediated signaling, cell recognition, cytoplasm, defense response to protozoan, immune system process, inflammatory response, innate immune response, integral component of membrane, intracellular membrane-bounded organelle, membrane, metal ion binding, MHC protein binding, nucleoplasm, pattern recognition receptor activity, pattern recognition receptor signaling pathway, phagocytosis, recognition, plasma membrane, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cytokine production involved in inflammatory response

related to Function · 23

CLEC7A → As, BCL10, CARD-CC/BCL10/MALT1, CARD9, CBM, Dimerization, IL-2, IL-23, IL-6, ITAM-like, Ligand, MALT1, NF-κB, Other, PKC-δ, Src, Syk, T-cells, The C-type, This

Bgee · 17

CLEC7A → appendix, blood, bone marrow, buccal mucosa cell, granulocyte, left lung, mesenteric lymph nodes, monocyte, mucous cell of stomach, periodontal fiber, right lung, right lung lobe, spleen, subcutaneous adipose tissue, tendon of biceps brachii, tibiofemoral joint, upper lobe of left lung

RNA expression pattern · 17

related to Antifungal immunity · 17

CLEC7A → Activation, Candida, CCL3, Coccidioides, CXCL2, G-CSF, GM-CSF, Histoplasma, IL-1α, IL-1β, IL-6, Penicillium, Pneumocystis, Recognition, Saccharomyces, Th17, TNF

related to Structure · 7

CLEC7A → C-type, CRD, Dectin-1, Expression, ITAM, N-linked, The CRD

related to Co-stimulatory molecule · 4

CLEC7A → Also, CD4, CD8, T-cells

Band · 2

CLEC7A → 12p13.2, 6|6 F3

Chr. · 2

CLEC7A → Chromosome 12 (human), Chromosome 6 (mouse)

End · 2

CLEC7A → 10,130,258 bp, 129,449,742 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene c-type bp cells domain human chromosome activation chr band lectin member receptor dectin-1 12 recognition family immune expression complex

CLEC7A relationships Subject–Predicate–Object triples

TTTA extracted 144 structured relationships around CLEC7A. Examples in this analysis include CLEC7A → Aliases → CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1, CD369, SCARE2, C-type lectin domain family 7 member A, C-type lectin domain containing 7A and CLEC7A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BPD, 2BPE, 2BPH, 2CL8. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CLEC7A	Aliases	CLEC7A, BGR, CANDF4, CLECSF12, DECTIN1, CD369, SCARE2, C-type lectin domain family 7 member A, C-type lectin domain containing 7A	1.00	infobox
CLEC7A	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BPD, 2BPE, 2BPH, 2CL8	1.00	infobox
CLEC7A	Band	12p13.2	1.00	infobox
CLEC7A	Band	6\|6 F3	1.00	infobox
CLEC7A	Bgee	monocyte	1.00	infobox
CLEC7A	Bgee	granulocyte	1.00	infobox
CLEC7A	Bgee	blood	1.00	infobox
CLEC7A	Bgee	buccal mucosa cell	1.00	infobox
CLEC7A	Bgee	periodontal fiber	1.00	infobox
CLEC7A	Bgee	tendon of biceps brachii	1.00	infobox
CLEC7A	Bgee	right lung	1.00	infobox
CLEC7A	Bgee	appendix	1.00	infobox
CLEC7A	Bgee	spleen	1.00	infobox
CLEC7A	Bgee	upper lobe of left lung	1.00	infobox
CLEC7A	Bgee	right lung lobe	1.00	infobox
CLEC7A	Bgee	mesenteric lymph nodes	1.00	infobox
CLEC7A	Bgee	tibiofemoral joint	1.00	infobox
CLEC7A	Bgee	bone marrow	1.00	infobox
CLEC7A	Bgee	left lung	1.00	infobox
CLEC7A	Bgee	mucous cell of stomach	1.00	infobox
CLEC7A	Bgee	subcutaneous adipose tissue	1.00	infobox
CLEC7A	BioGPS	More reference expression data	1.00	infobox
CLEC7A	Chr.	Chromosome 12 (human)	1.00	infobox
CLEC7A	Chr.	Chromosome 6 (mouse)	1.00	infobox
CLEC7A	Databases	NCBI: entry; OMA: entry	1.00	infobox
CLEC7A	End	10,130,258 bp	1.00	infobox
CLEC7A	End	129,449,742 bp	1.00	infobox
CLEC7A	Ensembl	ENSG00000172243	1.00	infobox
CLEC7A	Entrez	64581	1.00	infobox
CLEC7A	External IDs	OMIM: 606264; MGI: 1861431; GeneCards: CLEC7A	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CLEC7A bring nearby vocabulary together. In this analysis, examples include Domain, Cells and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CLEC7A
- Domain
- Cells
- Gene
- Lectin
- Location
- Member
- Human
- Recognition
- Protein
- Lectin-like
- Β-glucans
- Family
clec7a
- Domain
- Cells
- Gene
- Lectin
- Location
- Member
- Human
- Recognition
- Protein
- Lectin-like
- Β-glucans
- Family
gene
- Location
- Chromosome
- Human
- Bp
- Chr
- Protein
- Band
- Complex
- Lectin
- Member
- Region
- Ctl
immunoreceptor tyrosine-based activation motif
- Receptor
- Lectin-like
- Membrane
- Motif
- Complex
- Expression
- Triggers
- Also
- Dectin-1
- Domain
- Protein
- Recognition
dendritic cells
- Expression
- Recognition
- Clec7a
- Cells
- Dendritic
- Β-glucans
- Immune
- Via
- Also
- Phagocytosis
- Ligand
- Protein
b cells
- Expression
- Recognition
- Clec7a
- Dendritic
- Β-glucans
- Immune
- Via
- Also
- Protein
- Lectin-like
- Membrane
- Motif
β-glucans
- Receptor
- Dectin-1
- Recognition
- Cells
- Protein
- Lectin-like
- Membrane
- Motif
- Phagocytosis
- Band
- Clec7a
- Complex
c-type lectin receptors
- Domain
- Lectin
- Member
- Lectin-like
- Antifungal
- Encoded
- Gene
- Protein
- Clec7a
- Membrane
- Motif
- Family

Connections between topic areas Semantic bridges

For CLEC7A, one of the stronger structural bridges in this analysis connects CLEC7A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CLEC7A — Function · splits 15 ⟂ 42

CLEC7A — Overview · splits 48 ⟂ 9

CLEC7A — Structure · splits 52 ⟂ 5

Map overview Semantic statistics

CLEC7A

Nodes57

Edges56

Triples144

Avg. degree1.96

Density0.035088

Components1

Source & methodology

TTTA analyzes the structure around CLEC7A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CLEC7A · EN edition · Analysis: TopicsToTalkAbout