Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Langerin

Langerin (CD207) is a type II transmembrane protein which is encoded by the CD207 gene in humans. It was discovered by scientists Sem Saeland and Jenny Valladeau as a main part of Birbeck granules. Langerin is C-type lectin receptor on Langerhans cells (LCs) and in mice also on dermal interstitial CD103+ dendritic cells (DC) and on resident CD8+ DC in…

Art & Standards

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Langerin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CD207, CLEC4K, CD207 molecule
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3C22, 3KQG, 3P5D, 3P5E, 3P5F, 3P5G, 3P5H, 3P5I, 3P7F, 3P7G, 3P7H, 4AK8, 4N32, 4N33, 4N34, 4N35, 4N36, 4N37,…
Band
2p13.3 · 6|6 C3
Bgee
skin of thigh · skin of hip · skin of abdomen · skin of arm · vulva
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 6 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Polymorphism

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Langerin

Nodes71
Edges70
Triples135
Avg. degree1.97
Density0.028169
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Langerin

Top relations

Bgee · 19
Langerin → epithelium of esophagus, gingival epithelium, gums, left lobe of liver, lip, liver, neural layer of retina, nipple, oral cavity, right lung lobe, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, spleen, thymus, vulva
RNA expression pattern · 19
Langerin → epithelium of esophagus, gingival epithelium, gums, left lobe of liver, lip, liver, neural layer of retina, nipple, oral cavity, right lung lobe, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, spleen, thymus, vulva
related to Function · 19
Langerin → After, Birbeck, Candida, CD1a, For, HIV-1, In, It, LCs, MHC, MHC II, Mycobacterium, N-acetylglucosamine, Rab11a, Src, T-cells, There, These, Thus
related to Structure · 18
Langerin → All, C-type, Ca2, CRD, CRDs, DC-SIGN, DC-SIGNR, EPN, Glu-Pro-Asn, In, It, K299, K313, MBP, PRD, The, The CRD, These
related to Clinical significance · 15
Langerin → Birbeck, By, Candida, CD4, Furthermore, Gal-6-sulfated, HIV-1, If, In, LCs, Malassezia, Saccharomyces, Subsequently, T-cells, Thus
Gene ontology · 12
Langerin → antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, carbohydrate binding, clathrin-coated endocytic vesicle membrane, defense response to virus, early endosome membrane, endocytic vesicle, integral component of membrane, mannose binding, membrane, plasma membrane, protein binding, receptor-mediated endocytosis
related to Polymorphism · 7
Langerin → Allelic, Birbeck, BSA, Single, SNP, Substitution, The
Band · 2
Langerin → 2p13.3, 6|6 C3
Chr. · 2
Langerin → Chromosome 2 (human), Chromosome 6 (mouse)
End · 2
Langerin → 70,835,816 bp, 83,654,839 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

binding human bp lcs hiv-1 gene chr band birbeck antigen cd207 protein chromosome via virus dc-sign function granules polymorphism also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LangerinAliasesCD207, CLEC4K, CD207 molecule1.00infobox
LangerinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3C22, 3KQG, 3P5D, 3P5E, 3P5F, 3P5G, 3P5H, 3P5I, 3P7F, 3P7G, 3P7H, 4AK8, 4N32, 4N33, 4N34, 4N35, 4N36, 4N37,…1.00infobox
LangerinBand2p13.31.00infobox
LangerinBand6|6 C31.00infobox
LangerinBgeeskin of thigh1.00infobox
LangerinBgeeskin of hip1.00infobox
LangerinBgeeskin of abdomen1.00infobox
LangerinBgeeskin of arm1.00infobox
LangerinBgeevulva1.00infobox
LangerinBgeenipple1.00infobox
LangerinBgeeepithelium of esophagus1.00infobox
LangerinBgeeoral cavity1.00infobox
LangerinBgeegums1.00infobox
LangerinBgeegingival epithelium1.00infobox
LangerinBgeeskin of external ear1.00infobox
LangerinBgeethymus1.00infobox
LangerinBgeelip1.00infobox
LangerinBgeeliver1.00infobox
LangerinBgeespleen1.00infobox
LangerinBgeeleft lobe of liver1.00infobox
LangerinBgeeright lung lobe1.00infobox
LangerinBgeeskin of back1.00infobox
LangerinBgeeneural layer of retina1.00infobox
LangerinBioGPSMore reference expression data1.00infobox
LangerinChr.Chromosome 2 (human)1.00infobox
LangerinChr.Chromosome 6 (mouse)1.00infobox
LangerinDatabasesNCBI: entry; OMA: entry1.00infobox
LangerinEnd70,835,816 bp1.00infobox
LangerinEnd83,654,839 bp1.00infobox
LangerinEnsemblENSG000001160311.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.