CD44

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Explore the main themes, entities and connections around CD44. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Lymphocyte Hematopoiesis Tumor Metastasis Hyaluronic acid

20 related topics

CD44 in cancer

Cell proliferation Cell differentiation Cell migration Angiogenesis Cytokines

22 related topics

Interactions

Interact ARHGEF1 Ezrin PIP2 Epidermal Growth Factor Receptor

14 related topics

Clinical significance

Indian blood group system CD25 T cell Thymus CFSE

12 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 molecule (Indian blood group)
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1POZ, 1UUH, 2I83, 4PZ3, 4PZ4
Band: 11p13 · 2 E2|2 54.13 cM
Bgee: parotid gland · stromal cell of endometrium · vulva · gingival epithelium · skin of thigh
BioGPS: More reference expression data
Chr.: Chromosome 11 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Tissue distribution and isoforms

Isoform Protein isoform
Exons Exon
Epithelial cells Epithelium

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes82

Edges81

Triples158

Avg. degree1.98

Density0.02439

Components1

How this topic connects Entity context

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CD44

Top relations

Gene ontology · 48

CD44 → apical plasma membrane, basolateral plasma membrane, cartilage development, cell adhesion, cell migration, cell projection, cell surface, cell-cell adhesion, cell-matrix adhesion, cellular response to fibroblast growth factor stimulus, collagen binding, cytokine receptor activity, cytosol, extracellular exosome, extracellular matrix disassembly, extracellular matrix organization, focal adhesion, Golgi apparatus, hyaluronan catabolic process, hyaluronic acid binding

Bgee · 19

CD44 → Achilles tendon, body of femur, calvaria, dermis, endothelial cell of lymphatic vessel, epithelium of lens, gingival epithelium, granulocyte, human penis, islet of Langerhans, molar, parotid gland, skin of abdomen, skin of hip, skin of thigh, stromal cell of endometrium, submandibular gland, tibiofemoral joint, vulva

RNA expression pattern · 19

related to Interactions · 12

CD44 → ARHGEF1, CD74, Epidermal Growth Factor Receptor, Ezrin, Fibrin, Fibronectin, FYN, Hyaluronan, Hyaluronan-dependent, Lck, OsteopontinSelectins, PIP2

related to External links · 8

CD44 → BGMUT Blood Group Antigen, Gene Mutation Database, Human CD44, IHOP, Indian, NCBI, NIHArticles, UCSC Genome Browser

related to HCELL · 7

CD44 → E-selectin, Ex, HCELL, Hematopoietic Cell E-/L-selectin Ligand, It, L-selectin, The HCELL

related to Clinical significance · 6

CD44 → CD25, CFSE, Indian, Memory, T-cells, The

related to CD44 in cancer · 5

CD44 → All, CD44-soluble, Experiments, Furthermore, High

related to Tissue distribution and isoforms · 5

CD44 → CD44E, CD44s, CD44v, Some, The

related to Function · 4

CD44 → HCELL, Hematopoietic Cell E-selectin/L-selectin Ligand, MMPs, One

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cell cells gene human cancer hcell bp expression chromosome 11 adhesion chr band also antigen migration molecule receptor homing protein

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
CD44	Aliases	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 molecule (Indian blood group)	1.00	infobox
CD44	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1POZ, 1UUH, 2I83, 4PZ3, 4PZ4	1.00	infobox
CD44	Band	11p13	1.00	infobox
CD44	Band	2 E2\|2 54.13 cM	1.00	infobox
CD44	Bgee	parotid gland	1.00	infobox
CD44	Bgee	stromal cell of endometrium	1.00	infobox
CD44	Bgee	vulva	1.00	infobox
CD44	Bgee	gingival epithelium	1.00	infobox
CD44	Bgee	skin of thigh	1.00	infobox
CD44	Bgee	human penis	1.00	infobox
CD44	Bgee	skin of abdomen	1.00	infobox
CD44	Bgee	Achilles tendon	1.00	infobox
CD44	Bgee	skin of hip	1.00	infobox
CD44	Bgee	islet of Langerhans	1.00	infobox
CD44	Bgee	molar	1.00	infobox
CD44	Bgee	granulocyte	1.00	infobox
CD44	Bgee	calvaria	1.00	infobox
CD44	Bgee	dermis	1.00	infobox
CD44	Bgee	submandibular gland	1.00	infobox
CD44	Bgee	epithelium of lens	1.00	infobox
CD44	Bgee	tibiofemoral joint	1.00	infobox
CD44	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
CD44	Bgee	body of femur	1.00	infobox
CD44	BioGPS	More reference expression data	1.00	infobox
CD44	Chr.	Chromosome 11 (human)	1.00	infobox
CD44	Chr.	Chromosome 2 (mouse)	1.00	infobox
CD44	Databases	NCBI: entry; OMA: entry	1.00	infobox
CD44	End	35,232,402 bp	1.00	infobox
CD44	End	102,732,010 bp	1.00	infobox
CD44	Ensembl	ENSG00000026508	1.00	infobox

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Connections between topic areas Semantic bridges

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