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Ezrin: Interactions, Function & Structure

Ezrin, also known as cytovillin or villin-2, is a protein that in humans is encoded by the EZR gene.

Language: English [EN]
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Ezrin topic overview

The analysis highlights Interactions, Function and Structure as prominent areas in the source structure around Ezrin.

Related topics
33
Source areas
4
Connected nodes
37
Extracted relationships
184
Concept neighborhoods
16
Bridge connections
37

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 14 topics
Function · 13 topics
Structure · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EZR, CVIL, CVL, HEL-S-105, VIL2, Ezrin
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RM8, 4RMA, 4RM9, 1NI2
Band
6q25.3 · 17|17 A1
Bgee
ventricular zone · bronchial epithelial cell · ganglionic eminence · nasal epithelium · olfactory zone of nasal mucosa
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ezrin connects Entity context

The extracted context around Ezrin shows recurring relationship patterns in the source. For example, Ezrin → actin binding, actin cytoskeleton, actin cytoskeleton reorganization, actin filament, actin filament binding, actin filament bundle assembly, apical part of cell, apical plasma membrane, astral microtubule organization, astrocyte projection, ATPase binding, axon guidance, basolateral plasma membrane, brush border, cadherin binding, cell adhesion molecule binding, cell body, cell cortex, cell periphery, cell projection Another extracted example is Ezrin → bronchial epithelial cell, Epithelium of choroid plexus, epithelium of small intestine, epithelium of stomach, ganglionic eminence, Ileal epithelium, ileum, intestinal villus, jejunal mucosa, left colon, mucosa of paranasal sinus, mucous cell of stomach, nasal epithelium, olfactory zone of nasal mucosa, pyloric antrum, right adrenal cortex, right uterine tube, seminal vesicula, tendon of biceps brachii, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ezrin

Top relations

Gene ontology · 102
Ezrin → actin binding, actin cytoskeleton, actin cytoskeleton reorganization, actin filament, actin filament binding, actin filament bundle assembly, apical part of cell, apical plasma membrane, astral microtubule organization, astrocyte projection, ATPase binding, axon guidance, basolateral plasma membrane, brush border, cadherin binding, cell adhesion molecule binding, cell body, cell cortex, cell periphery, cell projection
Bgee · 20
Ezrin → bronchial epithelial cell, Epithelium of choroid plexus, epithelium of small intestine, epithelium of stomach, ganglionic eminence, Ileal epithelium, ileum, intestinal villus, jejunal mucosa, left colon, mucosa of paranasal sinus, mucous cell of stomach, nasal epithelium, olfactory zone of nasal mucosa, pyloric antrum, right adrenal cortex, right uterine tube, seminal vesicula, tendon of biceps brachii, ventricular zone
RNA expression pattern · 20
Ezrin → bronchial epithelial cell, Epithelium of choroid plexus, epithelium of small intestine, epithelium of stomach, ganglionic eminence, Ileal epithelium, ileum, intestinal villus, jejunal mucosa, left colon, mucosa of paranasal sinus, mucous cell of stomach, nasal epithelium, olfactory zone of nasal mucosa, pyloric antrum, right adrenal cortex, right uterine tube, seminal vesicula, tendon of biceps brachii, ventricular zone
related to Function · 15
Ezrin → Binding, C-terminus, CD44, EBP50, ERM, FERM, ICAM-2, It, N-terminus, NHERF, PIP2, T567, The, The N-terminus, This
related to Structure · 4
Ezrin → ERM, FERM, The C-terminus, The N-terminus
Band · 2
Ezrin → 17|17 A1, 6q25.3
Chr. · 2
Ezrin → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Ezrin → 158,819,368 bp, 7,050,183 bp
Aliases · 1
Ezrin → EZR, CVIL, CVL, HEL-S-105, VIL2, Ezrin
Available structures · 1
Ezrin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RM8, 4RMA, 4RM9, 1NI2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp protein gene chr human band chromosome ezr domain binding c-terminus n-terminus membrane location structure actin mouse function cytoskeleton erm

Ezrin relationships Subject–Predicate–Object triples

TTTA extracted 184 structured relationships around Ezrin. Examples in this analysis include Ezrin → Aliases → EZR, CVIL, CVL, HEL-S-105, VIL2, Ezrin and Ezrin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RM8, 4RMA, 4RM9, 1NI2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EzrinAliasesEZR, CVIL, CVL, HEL-S-105, VIL2, Ezrin1.00infobox
EzrinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4RM8, 4RMA, 4RM9, 1NI21.00infobox
EzrinBand6q25.31.00infobox
EzrinBand17|17 A11.00infobox
EzrinBgeeventricular zone1.00infobox
EzrinBgeebronchial epithelial cell1.00infobox
EzrinBgeeganglionic eminence1.00infobox
EzrinBgeenasal epithelium1.00infobox
EzrinBgeeolfactory zone of nasal mucosa1.00infobox
EzrinBgeemucosa of paranasal sinus1.00infobox
EzrinBgeetendon of biceps brachii1.00infobox
EzrinBgeeright adrenal cortex1.00infobox
EzrinBgeeright uterine tube1.00infobox
EzrinBgeejejunal mucosa1.00infobox
EzrinBgeeepithelium of stomach1.00infobox
EzrinBgeemucous cell of stomach1.00infobox
EzrinBgeeleft colon1.00infobox
EzrinBgeeepithelium of small intestine1.00infobox
EzrinBgeeintestinal villus1.00infobox
EzrinBgeeileum1.00infobox
EzrinBgeeseminal vesicula1.00infobox
EzrinBgeeIleal epithelium1.00infobox
EzrinBgeepyloric antrum1.00infobox
EzrinBgeeEpithelium of choroid plexus1.00infobox
EzrinBioGPSMore reference expression data1.00infobox
EzrinChr.Chromosome 6 (human)1.00infobox
EzrinChr.Chromosome 17 (mouse)1.00infobox
EzrinDatabasesNCBI: entry; OMA: entry1.00infobox
EzrinEnd158,819,368 bp1.00infobox
EzrinEnd7,050,183 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ezrin bring nearby vocabulary together. In this analysis, examples include Binding, Ezr and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ezrin
    • Binding
    • Ezr
    • Protein
    • Domain
    • N-terminus
    • Gene
    • Function
    • Regulatory
    • Search
    • Location
    • Structure
    • C-terminus
  • ezrin
    • Binding
    • Ezr
    • Protein
    • Domain
    • N-terminus
    • Gene
    • Function
    • Regulatory
    • Search
    • Location
    • Structure
    • C-terminus
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Cytoplasmic
    • End
    • Function
    • Kinase
    • Mouse
    • Search
    • Protein
  • c-terminus
    • Domain
    • N-terminus
    • Contains
    • Membrane
    • Ezrin
    • Cell
    • Cytoplasmic
    • Cytoskeleton
    • End
    • Function
    • Kinase
    • Mouse
  • actin
    • Membrane
    • Cytoskeleton
    • Plasma
    • C-terminus
    • N-terminus
    • Binding
    • Protein
    • Adhesion
    • Cell
    • Contains
    • Cytoplasmic
    • End
  • actin filaments
    • Membrane
    • Cytoskeleton
    • Plasma
    • C-terminus
    • N-terminus
    • Binding
    • Protein
    • Adhesion
    • Cell
    • Contains
    • Cytoplasmic
    • End
  • structure
    • Adhesion
    • Cell
    • Organization
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Contains
    • Cytoplasmic
    • Cytoskeleton
  • function
    • Search
    • Location
    • Structure
    • Chromosome
    • Human
    • Bp
    • Chr
    • Gene
    • Adhesion
    • Cell
    • Contains
    • Cytoplasmic

Connections between topic areas Semantic bridges

For Ezrin, one of the stronger structural bridges in this analysis connects Ezrin with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EzrinInteractions · splits 23 ⟂ 15
EzrinFunction · splits 24 ⟂ 14
EzrinStructure · splits 33 ⟂ 5
EzrinOverview · splits 35 ⟂ 3

Map overview Semantic statistics

Ezrin

Nodes38
Edges37
Triples184
Avg. degree1.95
Density0.052632
Components1

Source & methodology

TTTA analyzes the structure around Ezrin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ezrin · EN edition · Analysis: TopicsToTalkAbout

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