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Immortalised cell line

An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally…

Applications, Methods of generation & Relation to natural biology and pathology

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Methods of generation

HEK 293Epstein–Barr virusB lymphocytesExpressionProteins
26 related topics

Relation to natural biology and pathology

CancerousSomatic cellCell cycleHeLaHenrietta Lacks
7 related topics

Role and uses

MammalianHumanClonal populationToxicity
4 related topics

Overview

CellsMulticellular organismMutationCellular senescenceIn vitro
11 related topics

Topics to explore

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Overview

Relation to natural biology and pathology

Role and uses

Methods of generation

Advanced semantic analysis

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Map overview Semantic statistics

Immortalised cell line

Nodes53
Edges52
Triples36
Avg. degree1.96
Density0.037736
Components1

How this topic connects Entity context

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Immortalised cell line

Top relations

has method · 16
Immortalised cell line → African-American, Artificial, Barr, DNA, E1, Epstein, February, HEK, HeLa, Henrietta Lacks, Hybridoma, Introduction, Isolation, October, There, This
related to Relation to natural biology and pathology · 11
Immortalised cell line → Baltimore, Cancer, HeLa, Henrietta Lacks, Immortalised, Johns Hopkins Hospital, Maryland, Other, Some, The, There
related to Examples · 5
Immortalised cell line → A549, Henrietta LacksHEK, Most, North American, There
related to Role and uses · 3
Immortalised cell line → Immortalised, The, This
is a · 1
Immortalised cell line → population of cells from a multicellular organism that would normally not proliferate indefinitely but

Important terminology Word statistics

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Important terminology

cell cells lines immortalised line hela immortal normal multicellular biology also example human cancer used indefinitely type analysis vitro mutations

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Immortalised cell lineis apopulation of cells from a multicellular organism that would normally not proliferate indefinitely but0.90text
Immortalised cell linehas methodThere0.60section
Immortalised cell linehas methodIsolation0.60section
Immortalised cell linehas methodThis0.60section
Immortalised cell linehas methodHeLa0.60section
Immortalised cell linehas methodFebruary0.60section
Immortalised cell linehas methodHenrietta Lacks0.60section
Immortalised cell linehas methodAfrican-American0.60section
Immortalised cell linehas methodOctober0.60section
Immortalised cell linehas methodIntroduction0.60section
Immortalised cell linehas methodE10.60section
Immortalised cell linehas methodHEK0.60section

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