Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Tryptase

Tryptase (EC 3.4.21.59) is the most abundant secretory granule-derived serine proteinase contained in mast cells and has been used as a marker for mast cell activation. Club cells contain tryptase, which is believed to be responsible for cleaving the hemagglutinin surface protein of influenza A virus, thereby activating it and causing the symptoms of flu.

Applications, Physiology & Clinical use

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Tryptase. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA
enzyme data
CAS no.
97501-93-4
EC no.
3.4.21.59
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Clinical use

Physiology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Tryptase

Nodes22
Edges21
Triples25
Avg. degree1.91
Density0.090909
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Tryptase

Top relations

related to External links · 4
Tryptase → Medicine Medical Subject Headings, MeSH, National Library, Tryptases
related to Clinical use · 3
Tryptase → Elevated, FIP1L1-PDGFRA, Serum
related to Genes · 2
Tryptase → Human, Mouse
related to Physiology · 2
Tryptase → Mast, Trichinella
BRENDA · 1
Tryptase → enzyme data
CAS no. · 1
Tryptase → 97501-93-4
EC no. · 1
Tryptase → 3.4.21.59
ExPASy · 1
Tryptase → NiceZyme view
Gene Ontology · 1
Tryptase → AmiGO / QuickGO
KEGG · 1
Tryptase → enzyme entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mast cell cells reactions genes 21 59 serum levels elevated serine proteinase used proteins use anaphylaxis human hemagglutinin also less

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TryptaseBRENDAenzyme data1.00infobox
TryptaseCAS no.97501-93-41.00infobox
TryptaseEC no.3.4.21.591.00infobox
TryptaseExPASyNiceZyme view1.00infobox
TryptaseGene OntologyAmiGO / QuickGO1.00infobox
TryptaseKEGGenzyme entry1.00infobox
TryptaseMetaCycmetabolic pathway1.00infobox
TryptaseNCBIproteins1.00infobox
TryptasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
TryptasePMCarticles1.00infobox
TryptasePubMedarticles1.00infobox
TryptaseRheareactions1.00infobox
TryptaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.