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Beta cell

Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. Problems with beta cells can lead to disorders such as diabetes.

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Key facts & relationships

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Location
Pancreatic islet
FMA
85704
Function
Insulin secretion
Latin
endocrinocytus B; insulinocytus
TH
H3.04.02.0.00026

Topics to explore

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Overview

Function

Insulin synthesis

Insulin secretion

Other hormones secreted

Clinical significance

Research

Advanced semantic analysis

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Map overview Semantic statistics

Beta cell

Nodes49
Edges48
Triples100
Avg. degree1.96
Density0.040816
Components1

How this topic connects Entity context

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Beta cell

Top relations

related to Type 1 diabetes · 15
Beta cell → APCs, BMP4, CD4, CD8, Examples, However, In, Research, Targeted, The, Then, These, This, Two, Type
related to Insulin secretion · 12
Beta cell → As, At, ATP-sensitive, GLUT, GSIS, In, KATP, There, This, Under, Via, Voltage-gated
related to Type 2 diabetes · 12
Beta cell → Another, At, Degeneration, However, In, Increased, Indeed, It, Many, Research, The, Type
related to Insulin synthesis · 11
Beta cell → After, As, Beta, C-peptide, Golgi, Inside, N-terminal, RER, Subsequent, The, Then
related to Experimental techniques · 10
Beta cell → Another, Beta-cells, Concerning, Diabetes, For, Many, Mouse, NOD, TIRF, Tools
related to Function · 8
Beta cell → Amylin, Both, Following, Insulin, Recent, RNA-seq, The, These
related to Medications · 8
Beta cell → ATP-sensitive, DPP-4, GLP-1, Many, Second-generation, Sulfonylureas, The, These
related to Other hormones secreted · 5
Beta cell → Amylin, C-peptide, IAPP, It, The
related to Regeneration · 5
Beta cell → Because, In, RNA, Single-cell, These
related to Clinical significance · 2
Beta cell → Beta, Here

Important terminology Word statistics

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Important terminology

insulin cells beta diabetes glucose beta-cell cell function secretion levels amylin shown blood type calcium channels research pancreatic release human

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Beta cellFMA857041.00infobox
Beta cellFunctionInsulin secretion1.00infobox
Beta cellLatinendocrinocytus B; insulinocytus1.00infobox
Beta cellLocationPancreatic islet1.00infobox
Beta cellTHH3.04.02.0.000261.00infobox
diabetesinstance ofProblems with beta cells can lead to disorders0.80text
regular doses of insulininstance ofThe symptoms of diabetes can potentially be controlled with methods0.80text
sustaining a proper dietinstance ofThe symptoms of diabetes can potentially be controlled with methods0.80text
Beta cellrelated to Clinical significanceBeta0.60section
Beta cellrelated to Clinical significanceHere0.60section
Beta cellrelated to Experimental techniquesMany0.60section
Beta cellrelated to Experimental techniquesTools0.60section

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