Replication protein A

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Structure

Heterotrimer OB-folds (oligonucleotide/oligosaccharide binding)DNA-binding domains Single-stranded DNA Flexible linker

10 related topics

Functions

Endonucleases Polymerase DNA repair Meiosis Saccharomyces cerevisiae

9 related topics

Overview

Protein DNA Eukaryotic In vitro Replication

8 related topics

Key facts & relationships

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Function: damaged DNA binding, single-stranded DNA binding
Subunit name: Subunit nameGeneChromosomal locus Replication protein A1RPA1Chr. 17 p13.3 Replication protein A2RPA2Chr. 1 p35.3 Replication protein A3RPA3Chr. 7 p21.3

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Overview

Structure

Heterotrimer Protein trimer
OB-folds (oligonucleotide/oligosaccharide binding) OB-fold
DNA-binding domains DNA-binding domain
Single-stranded DNA Single-stranded binding protein
Flexible linker
N-terminal N-terminus
C-terminal C-terminus
Phosphorylation
CST complex
Stoichiometry

Functions

Advanced semantic analysis

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Map overview Semantic statistics

Nodes31

Edges30

Triples8

Avg. degree1.94

Density0.064516

Components1

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Replication protein A

Top relations

see also · 4

Replication protein A → A1Replication, A2Replication, A3, Single-stranded

Function · 1

Replication protein A → damaged DNA binding, single-stranded DNA binding

Subunit name · 1

Replication protein A → Subunit nameGeneChromosomal locus Replication protein A1RPA1Chr. 17 p13.3 Replication protein A2RPA2Chr. 1 p35.3 Replication protein A3RPA3Chr. 7 p21.3

Important terminology Word statistics

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Important terminology

replication rpa protein dna binding ssdna also single-stranded rpa2 repair recombination rpa1 chr heterotrimer dbds binds a1 a2 a3 rpa3

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Replication protein A	Function	damaged DNA binding, single-stranded DNA binding	1.00	infobox
Replication protein A	Subunit name	Subunit nameGeneChromosomal locus Replication protein A1RPA1Chr. 17 p13.3 Replication protein A2RPA2Chr. 1 p35.3 Replication protein A3RPA3Chr. 7 p21.3	1.00	infobox
nucleotide excision repair	instance of	recombination and repair processes	0.80	text
homologous recombination	instance of	recombination and repair processes	0.80	text
Replication protein A	see also	Single-stranded	0.60	section
Replication protein A	see also	A1Replication	0.60	section
Replication protein A	see also	A2Replication	0.60	section
Replication protein A	see also	A3	0.60	section

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