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In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal…
Disease, Function & Structure
Explore the main themes, entities and connections around CD4. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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cells hiv immune helper human bp cell gene viral surface chr band counts immunoglobulin mhc class protein chromosome 12 infection
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD4 | Aliases | CD4, CD4mut, CD4 molecule, OKT4D, IMD79 | 1.00 | infobox |
| CD4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CDH, 1CDI, 1CDJ, 1CDU, 1CDY, 1G9M, 1G9N, 1GC1, 1JL4, 1Q68, 1RZJ, 1RZK, 1WIO, 1WIP, 1WIQ, 2B4C, 2JKR, 2JKT,… | 1.00 | infobox |
| CD4 | Band | 12p13.31 | 1.00 | infobox |
| CD4 | Band | 6 F2|6 59.17 cM | 1.00 | infobox |
| CD4 | Bgee | granulocyte | 1.00 | infobox |
| CD4 | Bgee | monocyte | 1.00 | infobox |
| CD4 | Bgee | lymph node | 1.00 | infobox |
| CD4 | Bgee | spleen | 1.00 | infobox |
| CD4 | Bgee | appendix | 1.00 | infobox |
| CD4 | Bgee | gallbladder | 1.00 | infobox |
| CD4 | Bgee | thymus | 1.00 | infobox |
| CD4 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CD4 | Bgee | right lung | 1.00 | infobox |
| CD4 | Bgee | right lobe of liver | 1.00 | infobox |
| CD4 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CD4 | Bgee | blood | 1.00 | infobox |
| CD4 | Bgee | zygote | 1.00 | infobox |
| CD4 | Bgee | external carotid artery | 1.00 | infobox |
| CD4 | Bgee | internal carotid artery | 1.00 | infobox |
| CD4 | Bgee | superior frontal gyrus | 1.00 | infobox |
| CD4 | Bgee | molar | 1.00 | infobox |
| CD4 | BioGPS | n/a | 1.00 | infobox |
| CD4 | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| CD4 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| CD4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD4 | End | 6,820,799 bp | 1.00 | infobox |
| CD4 | End | 124,865,184 bp | 1.00 | infobox |
| CD4 | Ensembl | ENSG00000010610 | 1.00 | infobox |
| CD4 | Entrez | 920 | 1.00 | infobox |
| CD4 | External IDs | OMIM: 186940; MGI: 88335; GeneCards: CD4 | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
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