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Endogenization is the evolutionary process by which viral genetic material becomes stably integrated into the germline of a host organism and inherited by offspring through Mendelian inheritance. The integrated sequences become endogenous viral elements, which encompasses all inheritable virus-derived sequences regardless of virus type.
History, Mechanism & Outcome
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host viral viruses dna endogenous virus elements sequences germline reverse genomes across endogenized integration ltr giant rna genome may transcriptase
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Endogenization | is a | evolutionary process by which viral genetic material becomes stably integrated into the germline of a host organism and inherited by offspring through Mendelian inheritance | 0.90 | text |
| the incidental hijacking of host DNA repair pathways.Retroviruses are the most common source of endogenization | instance of | or through other means | 0.80 | text |
| as genomic integration is an obligatory step in their replication | instance of | or through other means | 0.80 | text |
| and can create endogenous retroviruses | instance of | or through other means | 0.80 | text |
| differential CpG dinucleotide depletion may cause ERV families in the same host to evolve at different rates.For ERVs loci shared across species | instance of | other factors | 0.80 | text |
| independently established divergence times between the lineages sharing the locus can calibrate a substitution rate for each LTR separately | instance of | other factors | 0.80 | text |
| rather than assuming a single fixed rate for both | instance of | other factors | 0.80 | text |
| dinoflagellates | instance of | These same virus families have a strong presence in insects but have been endogenized across plant species as well.In single-celled organisms | 0.80 | text |
| the frequency of EVEs correlates across genera with host LINE retroelement abundance | instance of | These same virus families have a strong presence in insects but have been endogenized across plant species as well.In single-celled organisms | 0.80 | text |
| and LINE-encoded reverse transcriptase sequences occur in close genomic proximity to insertion sites | instance of | These same virus families have a strong presence in insects but have been endogenized across plant species as well.In single-celled organisms | 0.80 | text |
| attesting to retroelement-driven reverse transcription as the primary endogenization mechanism | instance of | These same virus families have a strong presence in insects but have been endogenized across plant species as well.In single-celled organisms | 0.80 | text |
| Endogenization | related to Co-option | EVEs | 0.60 | section |
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