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Nevirapine

Nevirapine (NVP), sold under the brand name Viramune among others, is a medication used to treat and prevent HIV/AIDS, specifically HIV-1. It is generally recommended for use with other antiretroviral medications. It may be used to prevent mother to child spread during birth but is not recommended following other exposures. It is taken by mouth.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J05AG01 (WHO)
Bioavailability
93% ± 9%
CAS Number
129618-40-2 Y
ChEMBL
ChEMBL57 Y

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Overview

Medical uses

Adverse effects

Drug interactions

Mechanism of action

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Nevirapine

Nodes69
Edges68
Triples136
Avg. degree1.97
Density0.028986
Components1

How this topic connects Entity context

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Nevirapine

Top relations

related to Preventing mother-to-child transmission · 26
Nevirapine → African, Although, Another, Associated Press, AZT, During Breastfeeding, FDA, Force, HIV, HIVNET, However, Lamivudine/zidovudine, Moreover, NNRTI, NNRTI-containing, Prevent Mother-to-Child HIV Transmission, Public Health Service Task, September, Thailand, These
has effect · 22
Nevirapine → ART, CD4, DHHS, Drug Administration, Food, Force, However, HSRs, In, Johnson, More, NVP, NVP-based, Public Health Service Task, Severe, Stevens, Thailand, The, This, Treatment-experienced
related to history · 16
Nevirapine → Archived, Boehringer Ingelheim, Boehringer Ingelheim Pharmaceuticals, Drug Administration, Europe, FDA, Food, Hargrave, Inc, It, June, Karl, NNRTI, Patent, September, Wayback Machine
related to Drug interactions · 11
Nevirapine → Concomitant, CYP1A2, CYP2B6, CYP3A, CYP3A4, Hypericum, In, John's, On, Some, St
related to Mechanism of action · 11
Nevirapine → Both, DNA, HIV-2, NNRTI, NNRTI-binding, NNRTIs, NRTIs, RNA, RTIs, Therefore, Unlike
related to Society and culture · 11
Nevirapine → African AIDS, Bush's PEPFAR, Constitutional Court, Former, Health, HIV, In Minister, In South Africa, President George, South Africa, Treatment Action Campaign
related to Medical uses · 6
Nevirapine → ART, HIV, HIV-1, Monotherapy, PI, Some
Legal status · 3
Nevirapine → AU: S4 (Prescription only), EU: Rx-only, US: ℞-only
is a · 2
Nevirapine → development of mild or moderate rash, inducer of cytochrome P450 isoenzymes CYP3A4 and CYP2B6
3D model (JSmol) · 1
Nevirapine → Interactive image

Important terminology Word statistics

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Important terminology

may use liver treatment drug nnrti hiv severe first reverse rash drugs patients cd4 skin transcriptase approved health used prevent

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nevirapine3D model (JSmol)Interactive image1.00infobox
NevirapineAHFS/Drugs.comMonograph1.00infobox
NevirapineATC codeJ05AG01 (WHO)1.00infobox
NevirapineBioavailability93% ± 9%1.00infobox
NevirapineCAS Number129618-40-2 Y1.00infobox
NevirapineChEMBLChEMBL57 Y1.00infobox
NevirapineChemSpider4308 Y1.00infobox
NevirapineCompTox Dashboard (EPA)DTXSID70317971.00infobox
NevirapineDrugBankDB00238 Y1.00infobox
NevirapineECHA InfoCard100.117.2501.00infobox
NevirapineElimination half-life45 hours1.00infobox
NevirapineExcretionKidney: <6% (Parent drug) Bile duct <5% (Parent drug)1.00infobox
NevirapineFormulaC15H14N4O1.00infobox
NevirapineKEGGD00435 Y1.00infobox
NevirapineLegal statusAU: S4 (Prescription only)1.00infobox
NevirapineLegal statusUS: ℞-only1.00infobox
NevirapineLegal statusEU: Rx-only1.00infobox
NevirapineLicense dataUS DailyMed: Nevirapine1.00infobox
NevirapineMedlinePlusa6000351.00infobox
NevirapineMetabolismLiver1.00infobox
NevirapineMolar mass266.304 g·mol−11.00infobox
NevirapineNIAID ChemDB0018561.00infobox
NevirapinePregnancy categoryAU: B31.00infobox
NevirapinePronunciation/nəˈvirəpiːn/ nə-VIR-ə-peen1.00infobox
NevirapinePubChem CID44631.00infobox
NevirapineRoutes of administrationBy mouth1.00infobox
NevirapineTrade namesViramune1.00infobox
NevirapineUNII99DK7FVK1H1.00infobox
Nevirapineis adevelopment of mild or moderate rash0.90text
Nevirapineis ainducer of cytochrome P450 isoenzymes CYP3A4 and CYP2B60.90text

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