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Reverse-transcriptase inhibitor

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses.

Types, Overview & Mechanism of action

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Types

PhosphodiesterCompetitive substrate inhibitorsDNA synthesisNon-competitive inhibitorsPhosphate
24 related topics

Overview

Antiretroviral drugsHIVAIDSHepatitis BInhibit
29 related topics

Mechanism of action

RNADNA
2 related topics

Mechanisms of resistance to reverse transcriptase inhibitors

Pyrophosphorolysis
1 related topics

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Overview

Mechanism of action

Types

Mechanisms of resistance to reverse transcriptase inhibitors

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Map overview Semantic statistics

Reverse-transcriptase inhibitor

Nodes61
Edges60
Triples85
Avg. degree1.97
Density0.032787
Components1

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Reverse-transcriptase inhibitor

Top relations

related to Nucleoside analog reverse-transcriptase inhibitors (NARTIs or NRTIs) · 41
Reverse-transcriptase inhibitor → Abacavir, ABC, AIDS, AZT, Azvudine, Baraclude, Coviracil, Didanosine, DNA, Emtricitabine, Emtriva, Entecavir, Epivir, ETV, FDA, FDA-approved, FTC, HIV, Hivid, In
related to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) · 33
Reverse-transcriptase inhibitor → August, Belgium, Co, Delavirdine, Delstrigo, Doravirine, Edurant, Efavirenz, Elpida, Elpida Combi, Elsulfavirine, Etravirine, FDA, FDA-approved, Health, In, Intelence, It, May, Medical Research
related to Types · 10
Reverse-transcriptase inhibitor → NARTIs, NNRTIs, Non-nucleoside, NRTIs, NRTTIs, NtARTIs, NtRTIs, Nucleoside, Nucleotide, RTIs
see also · 1
Reverse-transcriptase inhibitor → Discovery

Important terminology Word statistics

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Important terminology

dna also reverse trade nrtis transcriptase hiv nucleotide name nnrtis drug viral inhibitors needed called mutations analog approved hepatitis ntrtis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Non-nucleoside0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)NNRTIs0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)In0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)This0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Rega Institute0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Medical Research0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Belgium0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Efavirenz0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Sustiva0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Stocrin0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Nevirapine0.60section
Reverse-transcriptase inhibitorrelated to Non-nucleoside reverse-transcriptase inhibitors (NNRTIs)Viramune0.60section

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