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Proto-oncogene tyrosine-protein kinase Src: Interactions, Structure & Overview

Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma), is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene. It belongs to a family of Src family kinases and is similar to the v-Src (viral Src) gene of Rous sarcoma virus.…

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Proto-oncogene tyrosine-protein kinase Src topic overview

The analysis highlights Interactions, Structure and Overview as prominent areas in the source structure around Proto-oncogene tyrosine-protein kinase Src.

Related topics
71
Source areas
6
Connected nodes
77
Extracted relationships
266
Concept neighborhoods
20
Bridge connections
77

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 25 topics
Overview · 19 topics
Structure · 19 topics
As a drug target · 5 topics
Function · 2 topics
Discovery · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.2
Aliases
SRC, ASV, SRC1, c-p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, THC6
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A07, 1A08, 1A09, 1A1A, 1A1B, 1A1C, 1A1E, 1FMK, 1HCS, 1HCT, 1KSW, 1O41, 1O42, 1O43, 1O44, 1O45, 1O46, 1O47,…
Band
20q11.23 · 2 H1|2 78.35 cM
Bgee
body of stomach · gallbladder · rectum · body of pancreas · transverse colon
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Structure

Function

As a drug target

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Proto-oncogene tyrosine-protein kinase Src connects Entity context

The extracted context around Proto-oncogene tyrosine-protein kinase Src shows recurring relationship patterns in the source. For example, Proto-oncogene tyrosine-protein kinase Src → actin filament, activation of protein kinase B activity, adherens junction organization, angiotensin-activated signaling pathway involved in heart process, ATP binding, axon guidance, bone resorption, branching involved in mammary gland duct morphogenesis, cadherin binding, caveola, cell adhesion, cell adhesion molecule binding, cell cycle, cell differentiation, cell migration, cell population proliferation, cell-cell adhesion, cellular response to fatty acid, cellular response to fluid shear stress, cellular response to hydrogen peroxide Another extracted example is Proto-oncogene tyrosine-protein kinase Src → aortic valve, ascending aorta, body of pancreas, body of stomach, body of uterus, dentate gyrus of hippocampal formation granule cell, ectocervix, external carotid artery, gallbladder, ganglionic eminence, internal carotid artery, jejunum, molar, mucosa of transverse colon, muscle layer of sigmoid colon, primary visual cortex, rectum, superior frontal gyrus, transverse colon, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Proto-oncogene tyrosine-protein kinase Src

Top relations

Gene ontology · 184
Proto-oncogene tyrosine-protein kinase Src → actin filament, activation of protein kinase B activity, adherens junction organization, angiotensin-activated signaling pathway involved in heart process, ATP binding, axon guidance, bone resorption, branching involved in mammary gland duct morphogenesis, cadherin binding, caveola, cell adhesion, cell adhesion molecule binding, cell cycle, cell differentiation, cell migration, cell population proliferation, cell-cell adhesion, cellular response to fatty acid, cellular response to fluid shear stress, cellular response to hydrogen peroxide
Bgee · 20
Proto-oncogene tyrosine-protein kinase Src → aortic valve, ascending aorta, body of pancreas, body of stomach, body of uterus, dentate gyrus of hippocampal formation granule cell, ectocervix, external carotid artery, gallbladder, ganglionic eminence, internal carotid artery, jejunum, molar, mucosa of transverse colon, muscle layer of sigmoid colon, primary visual cortex, rectum, superior frontal gyrus, transverse colon, ventricular zone
RNA expression pattern · 20
Proto-oncogene tyrosine-protein kinase Src → aortic valve, ascending aorta, body of pancreas, body of stomach, body of uterus, dentate gyrus of hippocampal formation granule cell, ectocervix, external carotid artery, gallbladder, ganglionic eminence, internal carotid artery, jejunum, molar, mucosa of transverse colon, muscle layer of sigmoid colon, primary visual cortex, rectum, superior frontal gyrus, transverse colon, ventricular zone
related to External links · 17
Proto-oncogene tyrosine-protein kinase Src → Cell Migration Gateway Archived, Family, Gene, Info, Kinases, Medicine Medical Subject Headings, MeSH, National Library, P12931, PDB, PDBe-KB, Proteopedia SRC, Proto-oncogene, Src, SRCVega, UniProt, Wayback MachineOverview
Band · 2
Proto-oncogene tyrosine-protein kinase Src → 2 H1|2 78.35 cM, 20q11.23
Chr. · 2
Proto-oncogene tyrosine-protein kinase Src → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
Proto-oncogene tyrosine-protein kinase Src → 157,471,862 bp, 37,406,050 bp
2.7.10.2 · 1
Proto-oncogene tyrosine-protein kinase Src → ↗
Aliases · 1
Proto-oncogene tyrosine-protein kinase Src → SRC, ASV, SRC1, c-p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, THC6
Available structures · 1
Proto-oncogene tyrosine-protein kinase Src → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A07, 1A08, 1A09, 1A1A, 1A1B, 1A1C, 1A1E, 1FMK, 1HCS, 1HCT, 1KSW, 1O41, 1O42, 1O43, 1O44, 1O45, 1O46, 1O47,…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

c-src src tyrosine gene kinase cancer activity kinases human bp cell growth protein chr band colon also proliferation breast sh2

Proto-oncogene tyrosine-protein kinase Src relationships Subject–Predicate–Object triples

TTTA extracted 266 structured relationships around Proto-oncogene tyrosine-protein kinase Src. Examples in this analysis include Proto-oncogene tyrosine-protein kinase Src → 2.7.10.2 → ↗ and Proto-oncogene tyrosine-protein kinase Src → Aliases → SRC, ASV, SRC1, c-p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, THC6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Proto-oncogene tyrosine-protein kinase Src2.7.10.21.00infobox
Proto-oncogene tyrosine-protein kinase SrcAliasesSRC, ASV, SRC1, c-p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, THC61.00infobox
Proto-oncogene tyrosine-protein kinase SrcAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A07, 1A08, 1A09, 1A1A, 1A1B, 1A1C, 1A1E, 1FMK, 1HCS, 1HCT, 1KSW, 1O41, 1O42, 1O43, 1O44, 1O45, 1O46, 1O47,…1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBand20q11.231.00infobox
Proto-oncogene tyrosine-protein kinase SrcBand2 H1|2 78.35 cM1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeebody of stomach1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeegallbladder1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeerectum1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeebody of pancreas1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeetransverse colon1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeganglionic eminence1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeectocervix1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeebody of uterus1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeemuscle layer of sigmoid colon1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeemucosa of transverse colon1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeedentate gyrus of hippocampal formation granule cell1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeexternal carotid artery1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeesuperior frontal gyrus1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeprimary visual cortex1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeinternal carotid artery1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeventricular zone1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeemolar1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeaortic valve1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeeascending aorta1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBgeejejunum1.00infobox
Proto-oncogene tyrosine-protein kinase SrcBioGPSMore reference expression data1.00infobox
Proto-oncogene tyrosine-protein kinase SrcChr.Chromosome 20 (human)1.00infobox
Proto-oncogene tyrosine-protein kinase SrcChr.Chromosome 2 (mouse)1.00infobox
Proto-oncogene tyrosine-protein kinase SrcDatabasesNCBI: entry; OMA: entry1.00infobox
Proto-oncogene tyrosine-protein kinase SrcEnd37,406,050 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Proto-oncogene tyrosine-protein kinase Src bring nearby vocabulary together. In this analysis, examples include Role, Family and Proto-oncogene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Proto-oncogene tyrosine-protein kinase Src
    • Role
    • Family
    • Proto-oncogene
    • Domain
    • Sh2
    • Cell
    • External
    • Expression
    • Src
    • Enzyme
    • Sarcoma
    • Progression
  • proto-oncogene tyrosine-protein kinase src
    • Tyrosine
    • Role
    • Src
    • Enzyme
    • Family
    • Proto-oncogene
    • Colon
    • Domain
    • Protein
    • Sh2
    • Cell
    • External
  • non-receptor tyrosine kinase
    • Tyrosine
    • Src
    • Enzyme
    • Proto-oncogene
    • Colon
    • Domain
    • Protein
    • Sh2
    • Activity
    • External
    • Cellular
    • Chromosome
  • gene
    • Virus
    • Sarcoma
    • Chromosome
    • Src
    • Bp
    • Chr
    • Protein
    • Human
    • Normal
    • Tyrosine
    • External
    • Enzyme
  • src family kinases
    • Kinases
    • Family
    • Src
    • Tyrosine
    • Cell
    • Receptor
    • Enzyme
    • Protein
    • Expression
    • Colon
    • Domain
    • Proliferation
  • rous sarcoma virus
    • Sarcoma
    • Virus
    • Cellular
    • Gene
    • External
    • Enzyme
    • Family
    • Band
    • Chromosome
    • Expression
    • Receptor
    • Regulation
  • sh2 domain
    • Sh2
    • Sh3
    • Receptor
    • Tyrosine
    • Protein
    • Kinase
    • Cell
    • External
    • Src
    • Enzyme
    • Band
    • Chromosome
  • sh3 domain
    • Sh2
    • Sh3
    • Receptor
    • Tyrosine
    • Protein
    • Kinase
    • Cell
    • External
    • Src
    • Enzyme
    • Band
    • Chromosome

Connections between topic areas Semantic bridges

For Proto-oncogene tyrosine-protein kinase Src, one of the stronger structural bridges in this analysis connects Proto-oncogene tyrosine-protein kinase Src with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Proto-oncogene tyrosine-protein kinase SrcInteractions · splits 52 ⟂ 26
Proto-oncogene tyrosine-protein kinase SrcOverview · splits 58 ⟂ 20
Proto-oncogene tyrosine-protein kinase SrcStructure · splits 58 ⟂ 20
Proto-oncogene tyrosine-protein kinase SrcAs a drug target · splits 72 ⟂ 6
Proto-oncogene tyrosine-protein kinase SrcFunction · splits 75 ⟂ 3

Map overview Semantic statistics

Proto-oncogene tyrosine-protein kinase Src

Nodes78
Edges77
Triples266
Avg. degree1.97
Density0.025641
Components1

Source & methodology

TTTA analyzes the structure around Proto-oncogene tyrosine-protein kinase Src to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Structure & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Proto-oncogene tyrosine-protein kinase Src · EN edition · Analysis: TopicsToTalkAbout

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