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Mitogen-activated protein kinase kinase

Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK).

Overview, Role in melanoma & As a drug target

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Overview

15 related topics

Role in melanoma

1 related topics

As a drug target

1 related topics

Key facts & relationships

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BRENDA
enzyme data
EC no.
2.7.12.2
ExPASy
NiceZyme view
KEGG
enzyme entry
MetaCyc
metabolic pathway
NCBI
proteins

Topics to explore

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Overview

Role in melanoma

As a drug target

Advanced semantic analysis

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Map overview Semantic statistics

Mitogen-activated protein kinase kinase

Nodes21
Edges20
Triples11
Avg. degree1.9
Density0.095238
Components1

How this topic connects Entity context

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Mitogen-activated protein kinase kinase

Top relations

BRENDA · 1
Mitogen-activated protein kinase kinase → enzyme data
EC no. · 1
Mitogen-activated protein kinase kinase → 2.7.12.2
ExPASy · 1
Mitogen-activated protein kinase kinase → NiceZyme view
KEGG · 1
Mitogen-activated protein kinase kinase → enzyme entry
MetaCyc · 1
Mitogen-activated protein kinase kinase → metabolic pathway
NCBI · 1
Mitogen-activated protein kinase kinase → proteins
PDB structures · 1
Mitogen-activated protein kinase kinase → RCSB PDB PDBe PDBsum
PMC · 1
Mitogen-activated protein kinase kinase → articles
PubMed · 1
Mitogen-activated protein kinase kinase → articles
Rhea · 1
Mitogen-activated protein kinase kinase → reactions

Important terminology Word statistics

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Important terminology

mek kinase mek1 mek2 mapk mkk3 mkk4 mkk6 erk map2k enzyme also 12 mitogen-activated protein map signal transduction melanoma phosphorylates

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mitogen-activated protein kinase kinaseBRENDAenzyme data1.00infobox
Mitogen-activated protein kinase kinaseEC no.2.7.12.21.00infobox
Mitogen-activated protein kinase kinaseExPASyNiceZyme view1.00infobox
Mitogen-activated protein kinase kinaseKEGGenzyme entry1.00infobox
Mitogen-activated protein kinase kinaseMetaCycmetabolic pathway1.00infobox
Mitogen-activated protein kinase kinaseNCBIproteins1.00infobox
Mitogen-activated protein kinase kinasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Mitogen-activated protein kinase kinasePMCarticles1.00infobox
Mitogen-activated protein kinase kinasePubMedarticles1.00infobox
Mitogen-activated protein kinase kinaseRheareactions1.00infobox
Mitogen-activated protein kinase kinaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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    Min side: 3
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