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HCK

Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene.

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9 related topics

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2 related topics

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2.7.10.2
Aliases
HCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AD5, 1BU1, 1QCF, 2C0I, 2C0O, 2C0T, 2HCK, 2HK5, 2OI3, 2OJ2, 3HCK, 3NHN, 3RBB, 3REA, 3REB, 3VRY, 3VRZ, 3VS0,…
Band
20q11.21 · 2 H1|2 75.41 cM
Bgee
monocyte · granulocyte · blood · spleen · bone marrow
BioGPS
More reference expression data

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Map overview Semantic statistics

HCK

Nodes14
Edges13
Triples165
Avg. degree1.86
Density0.142857
Components1

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HCK

Top relations

Gene ontology · 61
HCK → actin filament, ATP binding, caveola, cell adhesion, cell differentiation, cell junction, cell projection, cytokine-mediated signaling pathway, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytosol, exocytosis, extrinsic component of cytoplasmic side of plasma membrane, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, Golgi apparatus, immune system process, inflammatory response, innate immune response
Bgee · 17
HCK → appendix, blood, bone marrow, bone marrow cell, granulocyte, left lung, mesenteric lymph nodes, middle frontal gyrus, monocyte, periodontal fiber, rib, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, trabecular bone, transitional epithelium of urinary bladder
RNA expression pattern · 17
HCK → appendix, blood, bone marrow, bone marrow cell, granulocyte, left lung, mesenteric lymph nodes, middle frontal gyrus, monocyte, periodontal fiber, rib, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, trabecular bone, transitional epithelium of urinary bladder
related to Signaling · 17
HCK → Activated HCK, Bcr/Abl, C-terminal, CD45, IL-2, IL-6, IL-8, IL1b, In, MAPK/ERK, PI3K/AKT, STAT5, These, This, TLR4, TNF-a, Upon
related to Structure · 8
HCK → C-terminal, Next, SH, SH1, SH2, SH3, The, The N-terminal
related to Function · 7
HCK → CXCL12/CXCR4, However, It, LPS-induced, NLRP3, Src, This
related to Interactions · 6
HCK → ADAM15BCR, Cbl, ELMO1, Granulocyte, RAPGEF1, RAS
Band · 2
HCK → 2 H1|2 75.41 cM, 20q11.21
Chr. · 2
HCK → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
HCK → 152,993,361 bp, 32,101,856 bp

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Important terminology

bp gene chr human band tyrosine kinase chromosome 20 cell migration location signaling myeloid activity enzyme mouse residue inflammatory function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HCK2.7.10.21.00infobox
HCKAliasesHCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase1.00infobox
HCKAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AD5, 1BU1, 1QCF, 2C0I, 2C0O, 2C0T, 2HCK, 2HK5, 2OI3, 2OJ2, 3HCK, 3NHN, 3RBB, 3REA, 3REB, 3VRY, 3VRZ, 3VS0,…1.00infobox
HCKBand20q11.211.00infobox
HCKBand2 H1|2 75.41 cM1.00infobox
HCKBgeemonocyte1.00infobox
HCKBgeegranulocyte1.00infobox
HCKBgeeblood1.00infobox
HCKBgeespleen1.00infobox
HCKBgeebone marrow1.00infobox
HCKBgeeappendix1.00infobox
HCKBgeetrabecular bone1.00infobox
HCKBgeemiddle frontal gyrus1.00infobox
HCKBgeebone marrow cell1.00infobox
HCKBgeeperiodontal fiber1.00infobox
HCKBgeestroma of bone marrow1.00infobox
HCKBgeetibiofemoral joint1.00infobox
HCKBgeerib1.00infobox
HCKBgeemesenteric lymph nodes1.00infobox
HCKBgeeright lung lobe1.00infobox
HCKBgeetransitional epithelium of urinary bladder1.00infobox
HCKBgeeleft lung1.00infobox
HCKBioGPSMore reference expression data1.00infobox
HCKChr.Chromosome 20 (human)1.00infobox
HCKChr.Chromosome 2 (mouse)1.00infobox
HCKDatabasesNCBI: entry; OMA: entry1.00infobox
HCKEnd32,101,856 bp1.00infobox
HCKEnd152,993,361 bp1.00infobox
HCKEnsemblENSG000001013361.00infobox
HCKEntrez30551.00infobox

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