Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

HCK: Interactions & Overview

Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

HCK topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around HCK.

Related topics
11
Source areas
2
Connected nodes
13
Extracted relationships
165
Concept neighborhoods
6
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 9 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.2
Aliases
HCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AD5, 1BU1, 1QCF, 2C0I, 2C0O, 2C0T, 2HCK, 2HK5, 2OI3, 2OJ2, 3HCK, 3NHN, 3RBB, 3REA, 3REB, 3VRY, 3VRZ, 3VS0,…
Band
20q11.21 · 2 H1|2 75.41 cM
Bgee
monocyte · granulocyte · blood · spleen · bone marrow
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HCK connects Entity context

The extracted context around HCK shows recurring relationship patterns in the source. For example, HCK → actin filament, ATP binding, caveola, cell adhesion, cell differentiation, cell junction, cell projection, cytokine-mediated signaling pathway, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytosol, exocytosis, extrinsic component of cytoplasmic side of plasma membrane, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, Golgi apparatus, immune system process, inflammatory response, innate immune response Another extracted example is HCK → appendix, blood, bone marrow, bone marrow cell, granulocyte, left lung, mesenteric lymph nodes, middle frontal gyrus, monocyte, periodontal fiber, rib, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, trabecular bone, transitional epithelium of urinary bladder. Use these groups to spot repeated connection types before inspecting the individual relationships.

HCK

Top relations

Gene ontology · 61
HCK → actin filament, ATP binding, caveola, cell adhesion, cell differentiation, cell junction, cell projection, cytokine-mediated signaling pathway, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytosol, exocytosis, extrinsic component of cytoplasmic side of plasma membrane, Fc-gamma receptor signaling pathway involved in phagocytosis, focal adhesion, Golgi apparatus, immune system process, inflammatory response, innate immune response
Bgee · 17
HCK → appendix, blood, bone marrow, bone marrow cell, granulocyte, left lung, mesenteric lymph nodes, middle frontal gyrus, monocyte, periodontal fiber, rib, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, trabecular bone, transitional epithelium of urinary bladder
RNA expression pattern · 17
HCK → appendix, blood, bone marrow, bone marrow cell, granulocyte, left lung, mesenteric lymph nodes, middle frontal gyrus, monocyte, periodontal fiber, rib, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, trabecular bone, transitional epithelium of urinary bladder
related to Signaling · 17
HCK → Activated HCK, Bcr/Abl, C-terminal, CD45, IL-2, IL-6, IL-8, IL1b, In, MAPK/ERK, PI3K/AKT, STAT5, These, This, TLR4, TNF-a, Upon
related to Structure · 8
HCK → C-terminal, Next, SH, SH1, SH2, SH3, The, The N-terminal
related to Function · 7
HCK → CXCL12/CXCR4, However, It, LPS-induced, NLRP3, Src, This
related to Interactions · 6
HCK → ADAM15BCR, Cbl, ELMO1, Granulocyte, RAPGEF1, RAS
Band · 2
HCK → 2 H1|2 75.41 cM, 20q11.21
Chr. · 2
HCK → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
HCK → 152,993,361 bp, 32,101,856 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band tyrosine kinase chromosome 20 cell migration location signaling myeloid activity enzyme mouse residue inflammatory function

HCK relationships Subject–Predicate–Object triples

TTTA extracted 165 structured relationships around HCK. Examples in this analysis include HCK → 2.7.10.2 → ↗ and HCK → Aliases → HCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HCK2.7.10.21.00infobox
HCKAliasesHCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase1.00infobox
HCKAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AD5, 1BU1, 1QCF, 2C0I, 2C0O, 2C0T, 2HCK, 2HK5, 2OI3, 2OJ2, 3HCK, 3NHN, 3RBB, 3REA, 3REB, 3VRY, 3VRZ, 3VS0,…1.00infobox
HCKBand20q11.211.00infobox
HCKBand2 H1|2 75.41 cM1.00infobox
HCKBgeemonocyte1.00infobox
HCKBgeegranulocyte1.00infobox
HCKBgeeblood1.00infobox
HCKBgeespleen1.00infobox
HCKBgeebone marrow1.00infobox
HCKBgeeappendix1.00infobox
HCKBgeetrabecular bone1.00infobox
HCKBgeemiddle frontal gyrus1.00infobox
HCKBgeebone marrow cell1.00infobox
HCKBgeeperiodontal fiber1.00infobox
HCKBgeestroma of bone marrow1.00infobox
HCKBgeetibiofemoral joint1.00infobox
HCKBgeerib1.00infobox
HCKBgeemesenteric lymph nodes1.00infobox
HCKBgeeright lung lobe1.00infobox
HCKBgeetransitional epithelium of urinary bladder1.00infobox
HCKBgeeleft lung1.00infobox
HCKBioGPSMore reference expression data1.00infobox
HCKChr.Chromosome 20 (human)1.00infobox
HCKChr.Chromosome 2 (mouse)1.00infobox
HCKDatabasesNCBI: entry; OMA: entry1.00infobox
HCKEnd32,101,856 bp1.00infobox
HCKEnd152,993,361 bp1.00infobox
HCKEnsemblENSG000001013361.00infobox
HCKEntrez30551.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around HCK bring nearby vocabulary together. In this analysis, examples include Cell, Migration and Kinase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HCK
    • Cell
    • Migration
    • Kinase
    • Myeloid
    • Gene
    • Tyrosine
    • Activity
    • Also
    • Domains
    • Inactive
    • Participates
    • Shown
  • hck
    • Cell
    • Migration
    • Kinase
    • Myeloid
    • Gene
    • Tyrosine
    • Activity
    • Also
    • Domains
    • Inactive
    • Participates
    • Shown
  • gene
    • Location
    • Chromosome
    • Human
    • Kinase
    • Bp
    • Chr
    • End
    • Function
    • H1
    • Mouse
    • Search
    • Activity
  • bcr gene
    • Location
    • Chromosome
    • Human
    • Kinase
    • Bp
    • Chr
    • End
    • Function
    • H1
    • Mouse
    • Search
    • Activity
  • cbl gene
    • Location
    • Chromosome
    • Human
    • Kinase
    • Bp
    • Chr
    • End
    • Function
    • H1
    • Mouse
    • Search
    • Activity
  • enzyme
    • Kinase
    • Gene
    • Function
    • Search
    • Activity
    • Location
    • Signaling
    • Chromosome
    • Human
    • Bp
    • Chr
    • Tyrosine

Connections between topic areas Semantic bridges

For HCK, one of the stronger structural bridges in this analysis connects HCK with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HCKInteractions · splits 4 ⟂ 10
HCKOverview · splits 11 ⟂ 3

Map overview Semantic statistics

HCK

Nodes14
Edges13
Triples165
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around HCK to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HCK · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.