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CASPR

CASPR also known as Contactin associated protein 1, Paranodin and CASPR1 is a protein that in humans is encoded by the CNTNAP1 gene. CASPR is a part of the neurexin family of proteins, hence its another name "Neurexin IV". CASPR is a membrane protein found in the neuronal membrane in the paranodal section of the axon] in myelinated neurons, between the…

Art, Function & Clinical

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Aliases
CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3
Band
17q21.2 · 11|11 D
Bgee
right hemisphere of cerebellum · Region I of hippocampus proper · postcentral gyrus · right frontal lobe · Brodmann area 46
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

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Clinical

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CASPR

Nodes18
Edges17
Triples92
Avg. degree1.89
Density0.111111
Components1

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CASPR

Top relations

Gene ontology · 27
CASPR → axon, cell adhesion, cell junction, central nervous system myelination, cytoskeleton organization, integral component of membrane, integral component of plasma membrane, membrane, myelin sheath, myelination in peripheral nervous system, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection development, neuron projection morphogenesis, neuronal action potential propagation, paranodal junction, paranodal junction assembly, paranode region of axon, positive regulation of signal transduction, presynaptic active zone membrane
Bgee · 19
CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote
RNA expression pattern · 19
CASPR → Brodmann area 46, Brodmann area 9, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, neural layer of retina, orbitofrontal cortex, perirhinal cortex, postcentral gyrus, prefrontal cortex, primary visual cortex, Region I of hippocampus proper, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, zygote
related to Function · 5
CASPR → Jan, Northern, PTPRZ1, RefSeq, The
Band · 2
CASPR → 11|11 D, 17q21.2
Chr. · 2
CASPR → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
CASPR → 101,081,550 bp, 42,699,993 bp
is a · 2
CASPR → membrane protein found in the neuronal membrane in the paranodal section of the axon, part of the neurexin family of proteins
Aliases · 1
CASPR → CNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN3
BioGPS · 1
CASPR → n/a

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Important terminology

gene protein bp cntnap1 human chr band contactin chromosome 17 associated location domain complex membrane paranodal axon juxtaparanode mouse neuronal

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CASPRAliasesCNTNAP1, CASPR, CNTNAP, NRXN4, P190, contactin associated protein 1, CHN31.00infobox
CASPRBand17q21.21.00infobox
CASPRBand11|11 D1.00infobox
CASPRBgeeright hemisphere of cerebellum1.00infobox
CASPRBgeeRegion I of hippocampus proper1.00infobox
CASPRBgeepostcentral gyrus1.00infobox
CASPRBgeeright frontal lobe1.00infobox
CASPRBgeeBrodmann area 461.00infobox
CASPRBgeesuperior frontal gyrus1.00infobox
CASPRBgeeorbitofrontal cortex1.00infobox
CASPRBgeelateral nuclear group of thalamus1.00infobox
CASPRBgeeprefrontal cortex1.00infobox
CASPRBgeeBrodmann area 91.00infobox
CASPRBgeedentate gyrus of hippocampal formation granule cell1.00infobox
CASPRBgeeprimary visual cortex1.00infobox
CASPRBgeecerebellar cortex1.00infobox
CASPRBgeeneural layer of retina1.00infobox
CASPRBgeezygote1.00infobox
CASPRBgeelumbar subsegment of spinal cord1.00infobox
CASPRBgeeperirhinal cortex1.00infobox
CASPRBgeesecondary oocyte1.00infobox
CASPRBgeeentorhinal cortex1.00infobox
CASPRBioGPSn/a1.00infobox
CASPRChr.Chromosome 17 (human)1.00infobox
CASPRChr.Chromosome 11 (mouse)1.00infobox
CASPRDatabasesNCBI: entry; OMA: entry1.00infobox
CASPREnd42,699,993 bp1.00infobox
CASPREnd101,081,550 bp1.00infobox
CASPREnsemblENSG000001087971.00infobox
CASPREntrez85061.00infobox

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