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BCAR1

Breast cancer anti-estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene.

Function, Structure & Cas-family

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Aliases
BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas family scaffolding protein, Cas family scaffold protein, BCAR1 scaffold protein, Cas family member
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WYX, 3T6G
Band
16q23.1 · 8|8 E1
Bgee
right hemisphere of cerebellum · ascending aorta · gastrocnemius muscle · apex of heart · mucosa of transverse colon
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

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Overview

Gene

Cas-family

Structure

Function

Advanced semantic analysis

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Map overview Semantic statistics

BCAR1

Nodes34
Edges33
Triples183
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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BCAR1

Top relations

Gene ontology · 36
BCAR1 → actin cytoskeleton, actin filament organization, actin filament reorganization, antigen receptor-mediated signaling pathway, B cell receptor signaling pathway, cell adhesion, cell chemotaxis, cell division, cell junction, cell migration, cell population proliferation, cellular response to hepatocyte growth factor stimulus, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, focal adhesion, G protein-coupled receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, insulin receptor signaling pathway, integrin-mediated signaling pathway
Bgee · 20
BCAR1 → apex of heart, ascending aorta, body of stomach, cerebellar cortex, condyle, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, fossa, gastrocnemius muscle, human kidney, internal carotid artery, motor neuron, mucosa of transverse colon, Paneth cell, pituitary gland, placenta, retinal pigment epithelium, right hemisphere of cerebellum, yolk sac
RNA expression pattern · 20
BCAR1 → apex of heart, ascending aorta, body of stomach, cerebellar cortex, condyle, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, fossa, gastrocnemius muscle, human kidney, internal carotid artery, motor neuron, mucosa of transverse colon, Paneth cell, pituitary gland, placenta, retinal pigment epithelium, right hemisphere of cerebellum, yolk sac
related to Structure · 16
BCAR1 → FAK, Following, G-protein, It, N-terminal Src-homology, PRR, SD, SFKs, SH2, SH3, Src, Src-binding, The, These, This, YxxP
related to Cas-family · 14
BCAR1 → Cas, Cas-L, CASS4, Crk-associated, EFS, Embryonal Fyn-associated, HEF-1, However, Human, NEDD9, Neural, Notably, The Cas, These Cas
related to Function · 14
BCAR1 → Additionally, Among, Both RTKs, Cas, Crk, Due, ECM, Integrin-mediated, Recent, RNA, RTK-dependent, RTKs, Src, These
related to External links · 11
BCAR1 → Bcar1 Info, Cell Migration GatewayHuman BCAR1, Human Breast, Mouse Breast, Overview, P56945, PDB, PDBe-KB, Q61140, UCSC Genome Browser, UniProt
related to Clinical significance · 9
BCAR1 → Altered, Conversely, Deregulated, Given, However, It, Overexpression, Since, The
related to Gene · 4
BCAR1 → BCAR1-iso1, Eight, RefSeq, The
Band · 2
BCAR1 → 16q23.1, 8|8 E1

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Important terminology

p130cas protein phosphorylation human cell gene cancer expression bp substrate tyrosine migration family domain adhesion chr band breast chromosome 16

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BCAR1AliasesBCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas family scaffolding protein, Cas family scaffold protein, BCAR1 scaffold protein, Cas family member1.00infobox
BCAR1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WYX, 3T6G1.00infobox
BCAR1Band16q23.11.00infobox
BCAR1Band8|8 E11.00infobox
BCAR1Bgeeright hemisphere of cerebellum1.00infobox
BCAR1Bgeeascending aorta1.00infobox
BCAR1Bgeegastrocnemius muscle1.00infobox
BCAR1Bgeeapex of heart1.00infobox
BCAR1Bgeemucosa of transverse colon1.00infobox
BCAR1Bgeebody of stomach1.00infobox
BCAR1BgeeDescending thoracic aorta1.00infobox
BCAR1Bgeehuman kidney1.00infobox
BCAR1Bgeeplacenta1.00infobox
BCAR1Bgeepituitary gland1.00infobox
BCAR1Bgeeendothelial cell of lymphatic vessel1.00infobox
BCAR1Bgeefossa1.00infobox
BCAR1BgeePaneth cell1.00infobox
BCAR1Bgeemotor neuron1.00infobox
BCAR1Bgeecondyle1.00infobox
BCAR1Bgeeretinal pigment epithelium1.00infobox
BCAR1Bgeeyolk sac1.00infobox
BCAR1Bgeeexternal carotid artery1.00infobox
BCAR1Bgeeinternal carotid artery1.00infobox
BCAR1Bgeecerebellar cortex1.00infobox
BCAR1BioGPSMore reference expression data1.00infobox
BCAR1Chr.Chromosome 16 (human)1.00infobox
BCAR1Chr.Chromosome 8 (mouse)1.00infobox
BCAR1DatabasesNCBI: entry; OMA: entry1.00infobox
BCAR1End75,268,053 bp1.00infobox
BCAR1End112,470,441 bp1.00infobox

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