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BCAR1: Function, Structure & Cas-family

Breast cancer anti-estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene.

Language: English [EN]
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BCAR1 topic overview

The analysis highlights Function, Structure and Cas-family as prominent areas in the source structure around BCAR1.

Related topics
28
Source areas
5
Connected nodes
33
Extracted relationships
183
Concept neighborhoods
15
Bridge connections
33

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 15 topics
Structure · 6 topics
Cas-family · 3 topics
Gene · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas family scaffolding protein, Cas family scaffold protein, BCAR1 scaffold protein, Cas family member
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WYX, 3T6G
Band
16q23.1 · 8|8 E1
Bgee
right hemisphere of cerebellum · ascending aorta · gastrocnemius muscle · apex of heart · mucosa of transverse colon
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Cas-family

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BCAR1 connects Entity context

The extracted context around BCAR1 shows recurring relationship patterns in the source. For example, BCAR1 → actin cytoskeleton, actin filament organization, actin filament reorganization, antigen receptor-mediated signaling pathway, B cell receptor signaling pathway, cell adhesion, cell chemotaxis, cell division, cell junction, cell migration, cell population proliferation, cellular response to hepatocyte growth factor stimulus, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, focal adhesion, G protein-coupled receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, insulin receptor signaling pathway, integrin-mediated signaling pathway Another extracted example is BCAR1 → apex of heart, ascending aorta, body of stomach, cerebellar cortex, condyle, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, fossa, gastrocnemius muscle, human kidney, internal carotid artery, motor neuron, mucosa of transverse colon, Paneth cell, pituitary gland, placenta, retinal pigment epithelium, right hemisphere of cerebellum, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

BCAR1

Top relations

Gene ontology · 36
BCAR1 → actin cytoskeleton, actin filament organization, actin filament reorganization, antigen receptor-mediated signaling pathway, B cell receptor signaling pathway, cell adhesion, cell chemotaxis, cell division, cell junction, cell migration, cell population proliferation, cellular response to hepatocyte growth factor stimulus, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, focal adhesion, G protein-coupled receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, insulin receptor signaling pathway, integrin-mediated signaling pathway
Bgee · 20
BCAR1 → apex of heart, ascending aorta, body of stomach, cerebellar cortex, condyle, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, fossa, gastrocnemius muscle, human kidney, internal carotid artery, motor neuron, mucosa of transverse colon, Paneth cell, pituitary gland, placenta, retinal pigment epithelium, right hemisphere of cerebellum, yolk sac
RNA expression pattern · 20
BCAR1 → apex of heart, ascending aorta, body of stomach, cerebellar cortex, condyle, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, fossa, gastrocnemius muscle, human kidney, internal carotid artery, motor neuron, mucosa of transverse colon, Paneth cell, pituitary gland, placenta, retinal pigment epithelium, right hemisphere of cerebellum, yolk sac
related to Structure · 16
BCAR1 → FAK, Following, G-protein, It, N-terminal Src-homology, PRR, SD, SFKs, SH2, SH3, Src, Src-binding, The, These, This, YxxP
related to Cas-family · 14
BCAR1 → Cas, Cas-L, CASS4, Crk-associated, EFS, Embryonal Fyn-associated, HEF-1, However, Human, NEDD9, Neural, Notably, The Cas, These Cas
related to Function · 14
BCAR1 → Additionally, Among, Both RTKs, Cas, Crk, Due, ECM, Integrin-mediated, Recent, RNA, RTK-dependent, RTKs, Src, These
related to External links · 11
BCAR1 → Bcar1 Info, Cell Migration GatewayHuman BCAR1, Human Breast, Mouse Breast, Overview, P56945, PDB, PDBe-KB, Q61140, UCSC Genome Browser, UniProt
related to Clinical significance · 9
BCAR1 → Altered, Conversely, Deregulated, Given, However, It, Overexpression, Since, The
related to Gene · 4
BCAR1 → BCAR1-iso1, Eight, RefSeq, The
Band · 2
BCAR1 → 16q23.1, 8|8 E1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

p130cas protein phosphorylation human cell gene cancer expression bp substrate tyrosine migration family domain adhesion chr band breast chromosome 16

BCAR1 relationships Subject–Predicate–Object triples

TTTA extracted 183 structured relationships around BCAR1. Examples in this analysis include BCAR1 → Aliases → BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas family scaffolding protein, Cas family scaffold protein, BCAR1 scaffold protein, Cas family member and BCAR1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WYX, 3T6G. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BCAR1AliasesBCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas family scaffolding protein, Cas family scaffold protein, BCAR1 scaffold protein, Cas family member1.00infobox
BCAR1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WYX, 3T6G1.00infobox
BCAR1Band16q23.11.00infobox
BCAR1Band8|8 E11.00infobox
BCAR1Bgeeright hemisphere of cerebellum1.00infobox
BCAR1Bgeeascending aorta1.00infobox
BCAR1Bgeegastrocnemius muscle1.00infobox
BCAR1Bgeeapex of heart1.00infobox
BCAR1Bgeemucosa of transverse colon1.00infobox
BCAR1Bgeebody of stomach1.00infobox
BCAR1BgeeDescending thoracic aorta1.00infobox
BCAR1Bgeehuman kidney1.00infobox
BCAR1Bgeeplacenta1.00infobox
BCAR1Bgeepituitary gland1.00infobox
BCAR1Bgeeendothelial cell of lymphatic vessel1.00infobox
BCAR1Bgeefossa1.00infobox
BCAR1BgeePaneth cell1.00infobox
BCAR1Bgeemotor neuron1.00infobox
BCAR1Bgeecondyle1.00infobox
BCAR1Bgeeretinal pigment epithelium1.00infobox
BCAR1Bgeeyolk sac1.00infobox
BCAR1Bgeeexternal carotid artery1.00infobox
BCAR1Bgeeinternal carotid artery1.00infobox
BCAR1Bgeecerebellar cortex1.00infobox
BCAR1BioGPSMore reference expression data1.00infobox
BCAR1Chr.Chromosome 16 (human)1.00infobox
BCAR1Chr.Chromosome 8 (mouse)1.00infobox
BCAR1DatabasesNCBI: entry; OMA: entry1.00infobox
BCAR1End75,268,053 bp1.00infobox
BCAR1End112,470,441 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BCAR1 bring nearby vocabulary together. In this analysis, examples include P130cas, Cell and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BCAR1
    • P130cas
    • Cell
    • Protein
    • Expression
    • Phosphorylation
    • Tyrosine
    • Cancer
    • Migration
    • Adhesion
    • Human
    • Cells
    • Gene
  • bcar1
    • P130cas
    • Cell
    • Protein
    • Expression
    • Phosphorylation
    • Tyrosine
    • Cancer
    • Migration
    • Adhesion
    • Human
    • Cells
    • Gene
  • protein
    • Family
    • Cas
    • Structural
    • Gene
    • P130cas
    • Adaptor
    • Pdb
    • Uniprot
    • Expression
    • Characterized
    • Multiple
    • Human
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • External
    • Mouse
    • Protein
    • Band
    • Migration
    • Expression
    • Cell
  • scaffold protein
    • Family
    • Cas
    • Structural
    • Gene
    • P130cas
    • Adaptor
    • Pdb
    • Uniprot
    • Expression
    • Characterized
    • Multiple
    • Human
  • cell adhesion
    • Signaling
    • Migration
    • Invasion
    • Proliferation
    • Human
    • P130cas
    • Adhesion
    • Cell
    • Tyrosine
    • Phosphorylation
    • Expression
    • Role
  • tyrosine phosphorylation
    • Phosphorylation
    • Tyrosine
    • P130cas
    • Cell
    • Bcar1
    • Cells
    • Substrate
    • Growth
    • Domain
    • Signaling
    • Adaptor
    • Characterized
  • cas family
    • Family
    • Protein
    • Proteins
    • Characterized
    • Substrate
    • Adaptor
    • Multiple
    • Structural
    • External
    • Human
    • P130cas
    • Pdb

Connections between topic areas Semantic bridges

For BCAR1, one of the stronger structural bridges in this analysis connects BCAR1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BCAR1Function · splits 18 ⟂ 16
BCAR1Structure · splits 27 ⟂ 7
BCAR1Cas-family · splits 30 ⟂ 4
BCAR1Overview · splits 31 ⟂ 3
BCAR1Gene · splits 31 ⟂ 3

Map overview Semantic statistics

BCAR1

Nodes34
Edges33
Triples183
Avg. degree1.94
Density0.058824
Components1

Source & methodology

TTTA analyzes the structure around BCAR1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Cas-family, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BCAR1 · EN edition · Analysis: TopicsToTalkAbout

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