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Tyrosine-protein kinase CSK also known as C-terminal Src kinase is an enzyme that, in humans, is encoded by the CSK gene. This enzyme phosphorylates tyrosine residues located in the C-terminal end of Src-family kinases (SFKs) including SRC, HCK, FYN, LCK, LYN and YES1.
The analysis highlights Role in development and regulation, Function and Mutations as prominent areas in the source structure around Tyrosine-protein kinase CSK.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Tyrosine-protein kinase CSK shows recurring relationship patterns in the source. For example, Tyrosine-protein kinase CSK → adaptive immune response, adherens junction organization, ATP binding, brain development, cell differentiation, cell-cell junction, cellular response to peptide hormone stimulus, central nervous system development, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, extracellular exosome, extrinsic component of cytoplasmic side of plasma membrane, identical protein binding, immune system process, innate immune response, kinase activity, membrane, membrane raft, metal ion binding Another extracted example is Tyrosine-protein kinase CSK → appendix, blood, bone marrow cell, gastrula, granulocyte, lip, lymph node, mesenteric lymph nodes, monocyte, mucosa of transverse colon, neural layer of retina, spleen, stromal cell of endometrium, thymus, tonsil, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
csk kinase bp gene chr human band c-terminal src phosphorylation location enzyme activity chromosome 15 tyrosine regulation tyrosine-protein end kinases
TTTA extracted 120 structured relationships around Tyrosine-protein kinase CSK. Examples in this analysis include Tyrosine-protein kinase CSK → 2.7.10.4 → ↗ and Tyrosine-protein kinase CSK → Aliases → CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase, C-terminal Src kinase. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Tyrosine-protein kinase CSK | 2.7.10.4 | ↗ | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Aliases | CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase, C-terminal Src kinase | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Available structures | Available structuresPDBOrtholog search: H3BU69 PDBe H3BU69 RCSB List of PDB id codes1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Band | 15q24.1 | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Band | 9 B|9 31.18 cM | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | granulocyte | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | monocyte | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | spleen | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | blood | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | lymph node | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | appendix | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | mucosa of transverse colon | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | tonsil | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | bone marrow cell | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | stromal cell of endometrium | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | thymus | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | neural layer of retina | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | lip | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | ventricular zone | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | yolk sac | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Bgee | gastrula | 1.00 | infobox |
| Tyrosine-protein kinase CSK | BioGPS | More reference expression data | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Chr. | Chromosome 15 (human) | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Tyrosine-protein kinase CSK | End | 74,803,198 bp | 1.00 | infobox |
| Tyrosine-protein kinase CSK | End | 57,560,914 bp | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Ensembl | ENSG00000103653 | 1.00 | infobox |
| Tyrosine-protein kinase CSK | Entrez | 1445 | 1.00 | infobox |
The concept neighborhoods around Tyrosine-protein kinase CSK bring nearby vocabulary together. In this analysis, examples include Kinase, Tyrosine-protein and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Tyrosine-protein kinase CSK, one of the stronger structural bridges in this analysis connects Tyrosine-protein kinase CSK with Role in development and regulation. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Tyrosine-protein kinase CSK to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role in development and regulation, Function & Mutations, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Tyrosine-protein kinase CSK · EN edition · Analysis: TopicsToTalkAbout