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Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice.
The analysis highlights Interactions, Function and Inhibitors as prominent areas in the source structure around HDAC3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around HDAC3 shows recurring relationship patterns in the source. For example, HDAC3 → cellular response to fluid shear stress, chromatin binding, chromatin organization, circadian regulation of gene expression, circadian rhythm, cyclin binding, cytoplasm, cytosol, enzyme binding, Golgi apparatus, histone deacetylase activity, histone deacetylase binding, histone deacetylase complex, histone deacetylation, histone H3 deacetylation, histone H4 deacetylation, hydrolase activity, mitotic spindle, NAD-dependent histone deacetylase activity (H3-K14 specific), negative regulation of apoptotic process Another extracted example is HDAC3 → CBFA2T3, CCND1, GATA1, GATA2, GPS2, GTF2I, HDAC4, HDAC5, HDAC7A, HDAC9, MAP3K7IP2, MAPK11, NCOR1, NCOR2, PMLRBBP4, PPARD, PPARG, RELA, RP, RUNX2. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
histone bp gene human deacetylase chr band mice chromosome intestinal enzyme function location chromatin activity mouse expression protein external commensal
TTTA extracted 168 structured relationships around HDAC3. Examples in this analysis include HDAC3 → 3.5.1.98 → ↗ and HDAC3 → Aliases → HDAC3, HD3, RPD3, RPD3-2, histone deacetylase 3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HDAC3 | 3.5.1.98 | ↗ | 1.00 | infobox |
| HDAC3 | Aliases | HDAC3, HD3, RPD3, RPD3-2, histone deacetylase 3 | 1.00 | infobox |
| HDAC3 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4A69 | 1.00 | infobox |
| HDAC3 | Band | n/a | 1.00 | infobox |
| HDAC3 | Band | 18 19.81 cM|18 B3 | 1.00 | infobox |
| HDAC3 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| HDAC3 | Bgee | right adrenal cortex | 1.00 | infobox |
| HDAC3 | Bgee | left adrenal gland | 1.00 | infobox |
| HDAC3 | Bgee | left adrenal cortex | 1.00 | infobox |
| HDAC3 | Bgee | skin of leg | 1.00 | infobox |
| HDAC3 | Bgee | granulocyte | 1.00 | infobox |
| HDAC3 | Bgee | skin of abdomen | 1.00 | infobox |
| HDAC3 | Bgee | anterior pituitary | 1.00 | infobox |
| HDAC3 | Bgee | right ovary | 1.00 | infobox |
| HDAC3 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| HDAC3 | Bgee | spermatocyte | 1.00 | infobox |
| HDAC3 | Bgee | ventricular zone | 1.00 | infobox |
| HDAC3 | Bgee | genital tubercle | 1.00 | infobox |
| HDAC3 | Bgee | tail of embryo | 1.00 | infobox |
| HDAC3 | Bgee | superior frontal gyrus | 1.00 | infobox |
| HDAC3 | Bgee | muscle of thigh | 1.00 | infobox |
| HDAC3 | Bgee | lip | 1.00 | infobox |
| HDAC3 | Bgee | yolk sac | 1.00 | infobox |
| HDAC3 | Bgee | primary visual cortex | 1.00 | infobox |
| HDAC3 | Bgee | neural tube | 1.00 | infobox |
| HDAC3 | BioGPS | More reference expression data | 1.00 | infobox |
| HDAC3 | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| HDAC3 | Chr. | Chromosome 18 (mouse) | 1.00 | infobox |
| HDAC3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HDAC3 | End | 141,636,870 bp | 1.00 | infobox |
The concept neighborhoods around HDAC3 bring nearby vocabulary together. In this analysis, examples include Gene, Histone and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For HDAC3, one of the stronger structural bridges in this analysis connects HDAC3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HDAC3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Inhibitors, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HDAC3 · EN edition · Analysis: TopicsToTalkAbout