Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene.
The analysis highlights Function, Interactions and Regulation as prominent areas in the source structure around IRF1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Explore different angles and find fresh ideas to shape your next piece of content.
Search suggestions related to this topic. Open a question to research it further; suggestions are not verified answers.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
You can skip this section if you’re here for content ideas and keyword inspiration.
The extracted context around IRF1 shows recurring relationship patterns in the source. For example, IRF1 → apoptotic process, blood coagulation, CD8-positive, alpha-beta T cell differentiation, cellular response to interferon-beta, cellular response to mechanical stimulus, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, immune system process, innate immune response, interferon-gamma-mediated signaling pathway, negative regulation of cell population proliferation, negative regulation of regulatory T cell differentiation, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus Another extracted example is IRF1 → colon, corneal stroma, duodenum, granulocyte, ileum, jejunum, large intestine, mesenteric lymph nodes, primary oocyte, spleen. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
interferon factor irf-1 regulatory protein transcription bp gene function shown chr mouse band expression dna binding response regulation external domain
TTTA extracted 79 structured relationships around IRF1. Examples in this analysis include IRF1 → Aliases → IRF1, IRF-1, MAR, interferon regulatory factor 1 and IRF1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IF1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRF1 | Aliases | IRF1, IRF-1, MAR, interferon regulatory factor 1 | 1.00 | infobox |
| IRF1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IF1 | 1.00 | infobox |
| IRF1 | Band | 11 B1.3|11 32.0 cM | 1.00 | infobox |
| IRF1 | Bgee | granulocyte | 1.00 | infobox |
| IRF1 | Bgee | jejunum | 1.00 | infobox |
| IRF1 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| IRF1 | Bgee | duodenum | 1.00 | infobox |
| IRF1 | Bgee | corneal stroma | 1.00 | infobox |
| IRF1 | Bgee | large intestine | 1.00 | infobox |
| IRF1 | Bgee | spleen | 1.00 | infobox |
| IRF1 | Bgee | colon | 1.00 | infobox |
| IRF1 | Bgee | ileum | 1.00 | infobox |
| IRF1 | Bgee | primary oocyte | 1.00 | infobox |
| IRF1 | BioGPS | More reference expression data | 1.00 | infobox |
| IRF1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| IRF1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRF1 | End | 53,669,200 bp | 1.00 | infobox |
| IRF1 | Ensembl | ENSG00000125347 | 1.00 | infobox |
| IRF1 | Entrez | 3659 | 1.00 | infobox |
| IRF1 | External IDs | OMIM: 147575; MGI: 96590; GeneCards: IRF1 | 1.00 | infobox |
| IRF1 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11 B1.3|11 32.0 cMStart53,660,841 bpEnd53,669,200 bp | 1.00 | infobox |
| IRF1 | Gene ontology | DNA binding | 1.00 | infobox |
| IRF1 | Gene ontology | sequence-specific DNA binding | 1.00 | infobox |
| IRF1 | Gene ontology | DNA-binding transcription factor activity | 1.00 | infobox |
| IRF1 | Gene ontology | DNA-binding transcription activator activity, RNA polymerase II-specific | 1.00 | infobox |
| IRF1 | Gene ontology | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 1.00 | infobox |
| IRF1 | Gene ontology | protein binding | 1.00 | infobox |
| IRF1 | Gene ontology | DNA-binding transcription factor activity, RNA polymerase II-specific | 1.00 | infobox |
| IRF1 | Gene ontology | cytoplasm | 1.00 | infobox |
| IRF1 | Gene ontology | cytosol | 1.00 | infobox |
The concept neighborhoods around IRF1 bring nearby vocabulary together. In this analysis, examples include Regulatory, B1 and Chromosome. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IRF1, one of the stronger structural bridges in this analysis connects IRF1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IRF1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IRF1 · EN edition · Analysis: TopicsToTalkAbout
