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IRF1

Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene.

Interactions, Function & Regulation

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Interactions

12 related topics

Function

11 related topics

Regulation

2 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
IRF1, IRF-1, MAR, interferon regulatory factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IF1
Band
11 B1.3|11 32.0 cM
Bgee
granulocyte · jejunum · mesenteric lymph nodes · duodenum · corneal stroma
BioGPS
More reference expression data
Chr.
Chromosome 11 (mouse)

Topics to explore

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Overview

Function

Regulation

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

IRF1

Nodes32
Edges31
Triples85
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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IRF1

Top relations

Gene ontology · 38
IRF1 → apoptotic process, blood coagulation, CD8-positive, alpha-beta T cell differentiation, cellular response to interferon-beta, cellular response to mechanical stimulus, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, immune system process, innate immune response, interferon-gamma-mediated signaling pathway, negative regulation of cell population proliferation, negative regulation of regulatory T cell differentiation, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus
Bgee · 10
IRF1 → colon, corneal stroma, duodenum, granulocyte, ileum, jejunum, large intestine, mesenteric lymph nodes, primary oocyte, spleen
RNA expression pattern · 10
IRF1 → colon, corneal stroma, duodenum, granulocyte, ileum, jejunum, large intestine, mesenteric lymph nodes, primary oocyte, spleen
related to External links · 6
IRF1 → FactorBookIRF1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library
related to Interactions · 2
IRF1 → CHIPGAGEHSP70, HSP90IRF8KPNA2MYD88PCAFSTAT1TATVEGFR2REDD2
Aliases · 1
IRF1 → IRF1, IRF-1, MAR, interferon regulatory factor 1
Available structures · 1
IRF1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IF1
Band · 1
IRF1 → 11 B1.3|11 32.0 cM
BioGPS · 1
IRF1 → More reference expression data
Chr. · 1
IRF1 → Chromosome 11 (mouse)

Important terminology Word statistics

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Important terminology

interferon factor irf-1 regulatory protein transcription bp gene function shown chr mouse band expression dna binding response regulation external domain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
IRF1AliasesIRF1, IRF-1, MAR, interferon regulatory factor 11.00infobox
IRF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IF11.00infobox
IRF1Band11 B1.3|11 32.0 cM1.00infobox
IRF1Bgeegranulocyte1.00infobox
IRF1Bgeejejunum1.00infobox
IRF1Bgeemesenteric lymph nodes1.00infobox
IRF1Bgeeduodenum1.00infobox
IRF1Bgeecorneal stroma1.00infobox
IRF1Bgeelarge intestine1.00infobox
IRF1Bgeespleen1.00infobox
IRF1Bgeecolon1.00infobox
IRF1Bgeeileum1.00infobox
IRF1Bgeeprimary oocyte1.00infobox
IRF1BioGPSMore reference expression data1.00infobox
IRF1Chr.Chromosome 11 (mouse)1.00infobox
IRF1DatabasesNCBI: entry; OMA: entry1.00infobox
IRF1End53,669,200 bp1.00infobox
IRF1EnsemblENSG000001253471.00infobox
IRF1Entrez36591.00infobox
IRF1External IDsOMIM: 147575; MGI: 96590; GeneCards: IRF11.00infobox
IRF1Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11 B1.3|11 32.0 cMStart53,660,841 bpEnd53,669,200 bp1.00infobox
IRF1Gene ontologyDNA binding1.00infobox
IRF1Gene ontologysequence-specific DNA binding1.00infobox
IRF1Gene ontologyDNA-binding transcription factor activity1.00infobox
IRF1Gene ontologyDNA-binding transcription activator activity, RNA polymerase II-specific1.00infobox
IRF1Gene ontologyRNA polymerase II cis-regulatory region sequence-specific DNA binding1.00infobox
IRF1Gene ontologyprotein binding1.00infobox
IRF1Gene ontologyDNA-binding transcription factor activity, RNA polymerase II-specific1.00infobox
IRF1Gene ontologycytoplasm1.00infobox
IRF1Gene ontologycytosol1.00infobox

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