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DUSP10: Interactions & Overview

Dual specificity protein phosphatase 10 is an enzyme that in humans is encoded by the DUSP10 gene.

Language: English [EN]
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DUSP10 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around DUSP10.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
102
Concept neighborhoods
4
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.3.16
3.1.3.48
Aliases
DUSP10, MKP-5, MKP5, dual specificity phosphatase 10
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZZW, 2OUC, 2OUD, 3TG1
Band
1|1 H5
Bgee
secondary oocyte · stromal cell of endometrium · right lobe of liver · triceps brachii muscle · vastus lateralis muscle

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DUSP10 connects Entity context

The extracted context around DUSP10 shows recurring relationship patterns in the source. For example, DUSP10 → cytoplasm, cytosol, dephosphorylation, Golgi apparatus, hydrolase activity, JUN kinase binding, MAP kinase phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase p38 binding, negative regulation of cell migration, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, negative regulation of epithelium regeneration, negative regulation of ERK1 and ERK2 cascade, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of oligodendrocyte differentiation, negative regulation of p38MAPK cascade, negative regulation of protein kinase activity by regulation of protein phosphorylation, negative regulation of respiratory burst involved in inflammatory response Another extracted example is DUSP10 → amniotic fluid, body of pancreas, deltoid muscle, digastric muscle, masseter muscle, medial head of gastrocnemius muscle, monocyte, retinal pigment epithelium, right lobe of liver, secondary oocyte, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, thymus, triceps brachii muscle, vastus lateralis muscle, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

DUSP10

Top relations

Gene ontology · 40
DUSP10 → cytoplasm, cytosol, dephosphorylation, Golgi apparatus, hydrolase activity, JUN kinase binding, MAP kinase phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase p38 binding, negative regulation of cell migration, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, negative regulation of epithelium regeneration, negative regulation of ERK1 and ERK2 cascade, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of oligodendrocyte differentiation, negative regulation of p38MAPK cascade, negative regulation of protein kinase activity by regulation of protein phosphorylation, negative regulation of respiratory burst involved in inflammatory response
Bgee · 19
DUSP10 → amniotic fluid, body of pancreas, deltoid muscle, digastric muscle, masseter muscle, medial head of gastrocnemius muscle, monocyte, retinal pigment epithelium, right lobe of liver, secondary oocyte, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, thymus, triceps brachii muscle, vastus lateralis muscle, zygote
RNA expression pattern · 19
DUSP10 → amniotic fluid, body of pancreas, deltoid muscle, digastric muscle, masseter muscle, medial head of gastrocnemius muscle, monocyte, retinal pigment epithelium, right lobe of liver, secondary oocyte, skeletal muscle tissue, soleus muscle, sternocleidomastoid muscle, stromal cell of endometrium, temporal muscle, thymus, triceps brachii muscle, vastus lateralis muscle, zygote
related to Interactions · 2
DUSP10 → MAPK14, MAPK8
3.1.3.16 · 1
DUSP10 → ↗
3.1.3.48 · 1
DUSP10 → ↗
Aliases · 1
DUSP10 → DUSP10, MKP-5, MKP5, dual specificity phosphatase 10
Available structures · 1
DUSP10 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZZW, 2OUC, 2OUD, 3TG1
Band · 1
DUSP10 → 1|1 H5
BioGPS · 1
DUSP10 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene dual specificity protein mapk jnk p38 expression bp phosphatase chr phosphatases members erk sapk different subcellular localization stimuli enzyme

DUSP10 relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around DUSP10. Examples in this analysis include DUSP10 → 3.1.3.16 → ↗ and DUSP10 → Aliases → DUSP10, MKP-5, MKP5, dual specificity phosphatase 10. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DUSP103.1.3.161.00infobox
DUSP103.1.3.481.00infobox
DUSP10AliasesDUSP10, MKP-5, MKP5, dual specificity phosphatase 101.00infobox
DUSP10Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZZW, 2OUC, 2OUD, 3TG11.00infobox
DUSP10Band1|1 H51.00infobox
DUSP10Bgeesecondary oocyte1.00infobox
DUSP10Bgeestromal cell of endometrium1.00infobox
DUSP10Bgeeright lobe of liver1.00infobox
DUSP10Bgeetriceps brachii muscle1.00infobox
DUSP10Bgeevastus lateralis muscle1.00infobox
DUSP10Bgeeretinal pigment epithelium1.00infobox
DUSP10Bgeebody of pancreas1.00infobox
DUSP10Bgeedeltoid muscle1.00infobox
DUSP10Bgeemonocyte1.00infobox
DUSP10Bgeeamniotic fluid1.00infobox
DUSP10Bgeetemporal muscle1.00infobox
DUSP10Bgeesternocleidomastoid muscle1.00infobox
DUSP10Bgeezygote1.00infobox
DUSP10Bgeemedial head of gastrocnemius muscle1.00infobox
DUSP10Bgeeskeletal muscle tissue1.00infobox
DUSP10Bgeethymus1.00infobox
DUSP10Bgeemasseter muscle1.00infobox
DUSP10Bgeedigastric muscle1.00infobox
DUSP10Bgeesoleus muscle1.00infobox
DUSP10BioGPSMore reference expression data1.00infobox
DUSP10Chr.Chromosome 1 (mouse)1.00infobox
DUSP10DatabasesNCBI: entry1.00infobox
DUSP10End183,807,833 bp1.00infobox
DUSP10Ensembln/a1.00infobox
DUSP10Entrez112211.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DUSP10 bring nearby vocabulary together. In this analysis, examples include Phosphatase, Activity and Chromosome. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DUSP10
    • Phosphatase
    • Activity
    • Chromosome
    • Enzyme
    • Location
    • Mouse
    • Search
    • Bp
    • Chr
    • Gene
    • Protein
    • Specificity
  • dusp10
    • Phosphatase
    • Activity
    • Chromosome
    • Enzyme
    • Location
    • Mouse
    • Search
    • Bp
    • Chr
    • Gene
    • Protein
    • Specificity
  • gene
    • Phosphatase
    • Activity
    • Chromosome
    • Expressed
    • Location
    • Mouse
    • Search
    • Bp
    • Chr
    • Expression
    • Jnk
    • Mapk
  • enzyme
    • Dusp10
    • Phosphatase
    • Encoded
    • Humans
    • Specificity
    • Activity
    • Chromosome
    • Gene
    • Location
    • Mouse
    • Search
    • Bp

Connections between topic areas Semantic bridges

For DUSP10, one of the stronger structural bridges in this analysis connects DUSP10 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DUSP10Interactions · splits 4 ⟂ 4
DUSP10Overview · splits 5 ⟂ 3

Map overview Semantic statistics

DUSP10

Nodes8
Edges7
Triples102
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around DUSP10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DUSP10 · EN edition · Analysis: TopicsToTalkAbout

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