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MAP kinase kinase kinase

Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently, MAP kinase kinase activates MAP kinase. Several types of MAPKKK can exist but are mainly characterized by the MAP kinases they activate. MAPKKKs are stimulated by a large range…

Overview, Classes of MAPKKK and their functions & Clinical significance

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Key facts & relationships

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BRENDA
enzyme data
CAS no.
146702-84-3
EC no.
2.7.11.25
ExPASy
NiceZyme view
KEGG
enzyme entry
MetaCyc
metabolic pathway

Topics to explore

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Overview

Classes of MAPKKK and their functions

Activation and deactivation of MAPKKK

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

MAP kinase kinase kinase

Nodes56
Edges55
Triples16
Avg. degree1.96
Density0.035714
Components1

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MAP kinase kinase kinase

Top relations

BRENDA · 1
MAP kinase kinase kinase → enzyme data
CAS no. · 1
MAP kinase kinase kinase → 146702-84-3
EC no. · 1
MAP kinase kinase kinase → 2.7.11.25
ExPASy · 1
MAP kinase kinase kinase → NiceZyme view
KEGG · 1
MAP kinase kinase kinase → enzyme entry
MetaCyc · 1
MAP kinase kinase kinase → metabolic pathway
NCBI · 1
MAP kinase kinase kinase → proteins
PDB structures · 1
MAP kinase kinase kinase → RCSB PDB PDBe PDBsum
PMC · 1
MAP kinase kinase kinase → articles
PubMed · 1
MAP kinase kinase kinase → articles

Important terminology Word statistics

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Important terminology

mapkkk map kinase mapkkks kinases several pathway p38 upstream regulated mapk activated cell pathways protein apoptosis growth jnk activates exist

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MAP kinase kinase kinaseBRENDAenzyme data1.00infobox
MAP kinase kinase kinaseCAS no.146702-84-31.00infobox
MAP kinase kinase kinaseEC no.2.7.11.251.00infobox
MAP kinase kinase kinaseExPASyNiceZyme view1.00infobox
MAP kinase kinase kinaseKEGGenzyme entry1.00infobox
MAP kinase kinase kinaseMetaCycmetabolic pathway1.00infobox
MAP kinase kinase kinaseNCBIproteins1.00infobox
MAP kinase kinase kinasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
MAP kinase kinase kinasePMCarticles1.00infobox
MAP kinase kinase kinasePubMedarticles1.00infobox
MAP kinase kinase kinaseRheareactions1.00infobox
MAP kinase kinase kinaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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