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MAPK12

Mitogen-activated protein kinase 12 (MAP kinase 12), also known as extracellular signal-regulated kinase 6 (ERK6) or stress-activated protein kinase 3 (SAPK3), is an enzyme that in humans is encoded by the MAPK12 gene.

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4 related topics

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2.7.11.24
Aliases
MAPK12, ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3, ERK-6, MAPK 12, mitogen-activated protein kinase 12
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CM8, 4QUM
Band
22q13.33 · 15|15 E3
Bgee
gastrocnemius muscle · muscle of thigh · triceps brachii muscle · vastus lateralis muscle · Skeletal muscle tissue of rectus abdominis
BioGPS
n/a

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MAPK12

Nodes9
Edges8
Triples89
Avg. degree1.78
Density0.222222
Components1

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MAPK12

Top relations

Gene ontology · 32
MAPK12 → ATP binding, cell cycle, cellular response to organic substance, cytoplasm, cytosol, DNA damage induced protein phosphorylation, intracellular signal transduction, kinase activity, magnesium ion binding, MAP kinase activity, MAPK cascade, metal ion binding, mitochondrion, muscle organ development, myoblast differentiation, negative regulation of cell cycle, nucleoplasm, nucleotide binding, nucleus, peptidyl-serine phosphorylation
Bgee · 16
MAPK12 → ankle, anterior pituitary, biceps brachii, digastric muscle, gastrocnemius muscle, glutes, medial head of gastrocnemius muscle, muscle of thigh, right hemisphere of cerebellum, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 16
MAPK12 → ankle, anterior pituitary, biceps brachii, digastric muscle, gastrocnemius muscle, glutes, medial head of gastrocnemius muscle, muscle of thigh, right hemisphere of cerebellum, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
Band · 2
MAPK12 → 15|15 E3, 22q13.33
Chr. · 2
MAPK12 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
MAPK12 → 50,261,716 bp, 89,024,906 bp
2.7.11.24 · 1
MAPK12 → ↗
Aliases · 1
MAPK12 → MAPK12, ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3, ERK-6, MAPK 12, mitogen-activated protein kinase 12
Available structures · 1
MAPK12 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CM8, 4QUM
BioGPS · 1
MAPK12 → n/a

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Important terminology

bp protein gene chr human band kinase chromosome 22 mitogen-activated map location enzyme mouse 12 erk6 sapk3 function extracellular stress-activated

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MAPK122.7.11.241.00infobox
MAPK12AliasesMAPK12, ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3, ERK-6, MAPK 12, mitogen-activated protein kinase 121.00infobox
MAPK12Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CM8, 4QUM1.00infobox
MAPK12Band22q13.331.00infobox
MAPK12Band15|15 E31.00infobox
MAPK12Bgeegastrocnemius muscle1.00infobox
MAPK12Bgeemuscle of thigh1.00infobox
MAPK12Bgeetriceps brachii muscle1.00infobox
MAPK12Bgeevastus lateralis muscle1.00infobox
MAPK12BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
MAPK12Bgeethoracic diaphragm1.00infobox
MAPK12Bgeeright hemisphere of cerebellum1.00infobox
MAPK12Bgeeanterior pituitary1.00infobox
MAPK12Bgeeglutes1.00infobox
MAPK12Bgeebiceps brachii1.00infobox
MAPK12Bgeetemporal muscle1.00infobox
MAPK12Bgeeankle1.00infobox
MAPK12Bgeetibialis anterior muscle1.00infobox
MAPK12Bgeedigastric muscle1.00infobox
MAPK12Bgeesternocleidomastoid muscle1.00infobox
MAPK12Bgeemedial head of gastrocnemius muscle1.00infobox
MAPK12BioGPSn/a1.00infobox
MAPK12Chr.Chromosome 22 (human)1.00infobox
MAPK12Chr.Chromosome 15 (mouse)1.00infobox
MAPK12DatabasesNCBI: entry; OMA: entry1.00infobox
MAPK12End50,261,716 bp1.00infobox
MAPK12End89,024,906 bp1.00infobox
MAPK12EnsemblENSG000001881301.00infobox
MAPK12Entrez63001.00infobox
MAPK12Enzyme activityEnzyme activityEC #BRENDAExPASyKEGGMetaCyc2.7.11.24↗↗↗↗1.00infobox

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