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Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around MAP2K6.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAP2K6 shows recurring relationship patterns in the source. For example, MAP2K6 → activation of protein kinase activity, apoptotic process, ATP binding, cardiac muscle contraction, cellular response to sorbitol, cytoplasm, cytoskeleton, cytosol, DNA damage induced protein phosphorylation, identical protein binding, kinase activity, MAP kinase kinase activity, MAPK cascade, negative regulation of cold-induced thermogenesis, nucleoplasm, nucleotide binding, nucleotide-binding oligomerization domain containing signaling pathway, nucleus, ovulation cycle process, peptidyl-tyrosine phosphorylation Another extracted example is MAP2K6 → biceps brachii, deltoid muscle, gastrocnemius muscle, mandibular prominence, maxillary prominence, mucosa of transverse colon, muscle of thigh, rectum, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, somite, sternocleidomastoid muscle, tail of embryo, temporal muscle, triceps brachii muscle, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp kinase chromosome 17 gene map chr human band protein mitogen-activated location enzyme mouse mapk function dual specificity also known
TTTA extracted 103 structured relationships around MAP2K6. Examples in this analysis include MAP2K6 → 2.7.12.2 → ↗ and MAP2K6 → Aliases → MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3, mitogen-activated protein kinase kinase 6. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAP2K6 | 2.7.12.2 | ↗ | 1.00 | infobox |
| MAP2K6 | Aliases | MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3, mitogen-activated protein kinase kinase 6 | 1.00 | infobox |
| MAP2K6 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2Y8O, 3ENM, 3FME, 3VN9 | 1.00 | infobox |
| MAP2K6 | Band | 17q24.3 | 1.00 | infobox |
| MAP2K6 | Band | 11|11 E1-E2 | 1.00 | infobox |
| MAP2K6 | Bgee | rectum | 1.00 | infobox |
| MAP2K6 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| MAP2K6 | Bgee | biceps brachii | 1.00 | infobox |
| MAP2K6 | Bgee | vastus lateralis muscle | 1.00 | infobox |
| MAP2K6 | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| MAP2K6 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| MAP2K6 | Bgee | triceps brachii muscle | 1.00 | infobox |
| MAP2K6 | Bgee | deltoid muscle | 1.00 | infobox |
| MAP2K6 | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| MAP2K6 | Bgee | muscle of thigh | 1.00 | infobox |
| MAP2K6 | Bgee | temporal muscle | 1.00 | infobox |
| MAP2K6 | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| MAP2K6 | Bgee | maxillary prominence | 1.00 | infobox |
| MAP2K6 | Bgee | somite | 1.00 | infobox |
| MAP2K6 | Bgee | mandibular prominence | 1.00 | infobox |
| MAP2K6 | Bgee | tail of embryo | 1.00 | infobox |
| MAP2K6 | BioGPS | More reference expression data | 1.00 | infobox |
| MAP2K6 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| MAP2K6 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| MAP2K6 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAP2K6 | End | 69,553,865 bp | 1.00 | infobox |
| MAP2K6 | End | 110,525,522 bp | 1.00 | infobox |
| MAP2K6 | Ensembl | ENSG00000108984 | 1.00 | infobox |
| MAP2K6 | Entrez | 5608 | 1.00 | infobox |
| MAP2K6 | Enzyme activity | Enzyme activityEC #BRENDAExPASyKEGGMetaCyc2.7.12.2↗↗↗↗ | 1.00 | infobox |
The concept neighborhoods around MAP2K6 bring nearby vocabulary together. In this analysis, examples include Mitogen-activated, Protein and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAP2K6, one of the stronger structural bridges in this analysis connects MAP2K6 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAP2K6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAP2K6 · EN edition · Analysis: TopicsToTalkAbout