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MAPK13: Function & Overview

Mitogen-activated protein kinase 13 (MAPK 13), also known as stress-activated protein kinase 4 (SAPK4), is an enzyme that in humans is encoded by the MAPK13 gene.

Language: English [EN]
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MAPK13 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around MAPK13.

Related topics
13
Source areas
2
Connected nodes
15
Extracted relationships
100
Related term clusters
8
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 11 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.24
↗
Aliases
MAPK13, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta, mitogen-activated protein kinase 13
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3COI, 4EYJ, 4EYM, 4MYG, 4YNO, 5EKO, 5EKN
Band
6p21.31 · 17|17 A3.3
Bgee
gums · mucosa of transverse colon · right adrenal gland · right adrenal cortex · gingival epithelium
BioGPS
n/a

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

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Advanced semantic analysis

How MAPK13 connects Entity context

The extracted context around MAPK13 shows recurring relationship patterns in the source. For example, MAPK13 → ATP binding, cell cycle, cellular response to anisomycin, cellular response to hydrogen peroxide, cellular response to interleukin-1, cellular response to organic substance, cellular response to sodium arsenite, cellular response to sorbitol, cellular response to UV, cytoplasm, cytosol, intracellular signal transduction, kinase activity, MAP kinase activity, MAPK cascade, nucleotide binding, nucleus, peptidyl-serine phosphorylation, phosphorylation, positive regulation of inflammatory response Another extracted example is MAPK13 → colon, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, gingival epithelium, granulocyte, gums, human penis, ileum, intestinal villus, jejunum, large intestine, left adrenal cortex, left adrenal gland, lip, mucosa of ileum, mucosa of transverse colon, parotid gland, right adrenal cortex, right adrenal gland. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAPK13

Top relations

Gene ontology · 31
MAPK13 → ATP binding, cell cycle, cellular response to anisomycin, cellular response to hydrogen peroxide, cellular response to interleukin-1, cellular response to organic substance, cellular response to sodium arsenite, cellular response to sorbitol, cellular response to UV, cytoplasm, cytosol, intracellular signal transduction, kinase activity, MAP kinase activity, MAPK cascade, nucleotide binding, nucleus, peptidyl-serine phosphorylation, phosphorylation, positive regulation of inflammatory response
Bgee · 20
MAPK13 → colon, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, gingival epithelium, granulocyte, gums, human penis, ileum, intestinal villus, jejunum, large intestine, left adrenal cortex, left adrenal gland, lip, mucosa of ileum, mucosa of transverse colon, parotid gland, right adrenal cortex, right adrenal gland
RNA expression pattern · 20
MAPK13 → colon, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, gingival epithelium, granulocyte, gums, human penis, ileum, intestinal villus, jejunum, large intestine, left adrenal cortex, left adrenal gland, lip, mucosa of ileum, mucosa of transverse colon, parotid gland, right adrenal cortex, right adrenal gland
Band · 2
MAPK13 → 17|17 A3.3, 6p21.31
Chr. · 2
MAPK13 → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
MAPK13 → 28,999,207 bp, 36,144,524 bp
2.7.11.24 · 1
MAPK13 → ↗
Aliases · 1
MAPK13 → MAPK13, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta, mitogen-activated protein kinase 13
Available structures · 1
MAPK13 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3COI, 4EYJ, 4EYM, 4MYG, 4YNO, 5EKO, 5EKN
BioGPS · 1
MAPK13 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

kinase bp gene chr human band protein chromosome map 13 mapk location transcription enzyme mouse cellular mitogen-activated stress-activated sapk4 function

MAPK13 relationships Subject–Predicate–Object triples

TTTA extracted 100 structured relationships around MAPK13. Examples in this analysis include MAPK13 → 2.7.11.24 → ↗ and MAPK13 → Aliases → MAPK13, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta, mitogen-activated protein kinase 13. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAPK132.7.11.24↗1.00infobox
MAPK13AliasesMAPK13, MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta, mitogen-activated protein kinase 131.00infobox
MAPK13Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3COI, 4EYJ, 4EYM, 4MYG, 4YNO, 5EKO, 5EKN1.00infobox
MAPK13Band6p21.311.00infobox
MAPK13Band17|17 A3.31.00infobox
MAPK13Bgeegums1.00infobox
MAPK13Bgeemucosa of transverse colon1.00infobox
MAPK13Bgeeright adrenal gland1.00infobox
MAPK13Bgeeright adrenal cortex1.00infobox
MAPK13Bgeegingival epithelium1.00infobox
MAPK13Bgeeleft adrenal gland1.00infobox
MAPK13Bgeemucosa of ileum1.00infobox
MAPK13Bgeehuman penis1.00infobox
MAPK13Bgeeleft adrenal cortex1.00infobox
MAPK13Bgeeparotid gland1.00infobox
MAPK13Bgeegranulocyte1.00infobox
MAPK13Bgeelip1.00infobox
MAPK13Bgeecrypt of lieberkuhn of small intestine1.00infobox
MAPK13Bgeeepithelium of stomach1.00infobox
MAPK13Bgeeduodenum1.00infobox
MAPK13Bgeelarge intestine1.00infobox
MAPK13Bgeeileum1.00infobox
MAPK13Bgeecolon1.00infobox
MAPK13Bgeeintestinal villus1.00infobox
MAPK13Bgeejejunum1.00infobox
MAPK13BioGPSn/a1.00infobox
MAPK13Chr.Chromosome 6 (human)1.00infobox
MAPK13Chr.Chromosome 17 (mouse)1.00infobox
MAPK13DatabasesNCBI: entry; OMA: entry1.00infobox
MAPK13End36,144,524 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around MAPK13 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAPK13
    • Protein
    • Gene
    • Activity
    • Function
    • Mitogen-activated
    • Sapk4
    • Search
    • Stress-activated
    • Location
    • Chromosome
    • Human
    • Bp
  • mapk13
    • Protein
    • Gene
    • Activity
    • Function
    • Mitogen-activated
    • Sapk4
    • Search
    • Stress-activated
    • Location
    • Chromosome
    • Human
    • Bp
  • gene
    • Location
    • Mapk
    • Mapk13
    • Protein
    • Chromosome
    • Human
    • A3
    • Activity
    • Bp
    • Chr
    • End
    • Function
  • map kinase
    • Kinases
    • Mapk
    • Mapk13
    • Protein
    • Regulation
    • Stress
    • Gene
    • Map
    • Transcription
    • Activity
    • Encoded
    • Enzyme
  • transcription
    • Regulation
    • Cellular
    • Map
    • Kinase
    • A3
    • Activity
    • Encoded
    • End
    • Function
    • Kinases
    • Mouse
    • Search
  • p38 map kinase
    • Kinases
    • Mapk
    • Mapk13
    • Protein
    • Regulation
    • Stress
    • Gene
    • Map
    • Transcription
    • Activity
    • Encoded
    • Enzyme
  • function
    • Activity
    • Search
    • Location
    • Mapk
    • Mapk13
    • Protein
    • Chromosome
    • Gene
    • Human
    • Reading
    • References
    • Bp
  • enzyme
    • Mitogen-activated
    • Sapk4
    • Mapk
    • Mapk13
    • Protein
    • Gene
    • Humans
    • Known
    • Reading
    • References
    • Activity
    • Encoded

Connections between topic areas Semantic bridges

For MAPK13, one of the stronger structural bridges in this analysis connects MAPK13 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAPK13 — Function · splits 4 ⟂ 12
MAPK13 — Overview · splits 13 ⟂ 3

Map overview Semantic statistics

MAPK13

Nodes16
Edges15
Triples100
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around MAPK13 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAPK13 · EN edition · Analysis: TopicsToTalkAbout

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