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MAPK11: Function, Interactions & Overview

Mitogen-activated protein kinase 11 is an enzyme that in humans is encoded by the MAPK11 gene.

Language: English [EN]
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MAPK11 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around MAPK11.

Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
101
Concept neighborhoods
13
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 11 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.24
Aliases
MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta, mitogen-activated protein kinase 11
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3GC8, 3GC9, 3GP0
Band
22q13.33 · 15|15 E3
Bgee
right frontal lobe · right hemisphere of cerebellum · Brodmann area 9 · middle temporal gyrus · cingulate gyrus
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAPK11 connects Entity context

The extracted context around MAPK11 shows recurring relationship patterns in the source. For example, MAPK11 → ATP binding, cellular response to interleukin-1, cellular response to organic substance, cytoplasm, cytosol, intracellular signal transduction, kinase activity, MAP kinase activity, negative regulation of cardiac muscle cell proliferation, nucleoplasm, nucleotide binding, nucleus, phosphorylation, positive regulation of erythrocyte differentiation, positive regulation of gene expression, positive regulation of muscle cell differentiation, protein binding, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activity Another extracted example is MAPK11 → anterior cingulate cortex, apex of heart, Brodmann area 23, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, ganglionic eminence, lumbar spinal ganglion, middle temporal gyrus, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior cervical ganglion, superior frontal gyrus, tail of embryo, ventricular zone, visual cortex. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAPK11

Top relations

Gene ontology · 30
MAPK11 → ATP binding, cellular response to interleukin-1, cellular response to organic substance, cytoplasm, cytosol, intracellular signal transduction, kinase activity, MAP kinase activity, negative regulation of cardiac muscle cell proliferation, nucleoplasm, nucleotide binding, nucleus, phosphorylation, positive regulation of erythrocyte differentiation, positive regulation of gene expression, positive regulation of muscle cell differentiation, protein binding, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activity
Bgee · 20
MAPK11 → anterior cingulate cortex, apex of heart, Brodmann area 23, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, ganglionic eminence, lumbar spinal ganglion, middle temporal gyrus, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior cervical ganglion, superior frontal gyrus, tail of embryo, ventricular zone, visual cortex
RNA expression pattern · 20
MAPK11 → anterior cingulate cortex, apex of heart, Brodmann area 23, Brodmann area 9, caudate nucleus, cerebellar cortex, cingulate gyrus, ganglionic eminence, lumbar spinal ganglion, middle temporal gyrus, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior cervical ganglion, superior frontal gyrus, tail of embryo, ventricular zone, visual cortex
Band · 2
MAPK11 → 15|15 E3, 22q13.33
Chr. · 2
MAPK11 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
MAPK11 → 50,270,767 bp, 89,033,831 bp
related to Interactions · 2
MAPK11 → HDAC3, Promyelocytic
2.7.11.24 · 1
MAPK11 → ↗
Aliases · 1
MAPK11 → MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta, mitogen-activated protein kinase 11
Available structures · 1
MAPK11 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3GC8, 3GC9, 3GP0

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

kinase bp protein gene chr human band map chromosome 22 mitogen-activated location enzyme mouse transcription 11 function external kinases encoded

MAPK11 relationships Subject–Predicate–Object triples

TTTA extracted 101 structured relationships around MAPK11. Examples in this analysis include MAPK11 → 2.7.11.24 → ↗ and MAPK11 → Aliases → MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta, mitogen-activated protein kinase 11. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAPK112.7.11.241.00infobox
MAPK11AliasesMAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta, mitogen-activated protein kinase 111.00infobox
MAPK11Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3GC8, 3GC9, 3GP01.00infobox
MAPK11Band22q13.331.00infobox
MAPK11Band15|15 E31.00infobox
MAPK11Bgeeright frontal lobe1.00infobox
MAPK11Bgeeright hemisphere of cerebellum1.00infobox
MAPK11BgeeBrodmann area 91.00infobox
MAPK11Bgeemiddle temporal gyrus1.00infobox
MAPK11Bgeecingulate gyrus1.00infobox
MAPK11Bgeeanterior cingulate cortex1.00infobox
MAPK11Bgeeapex of heart1.00infobox
MAPK11Bgeecaudate nucleus1.00infobox
MAPK11BgeeBrodmann area 231.00infobox
MAPK11Bgeeputamen1.00infobox
MAPK11Bgeelumbar spinal ganglion1.00infobox
MAPK11Bgeeventricular zone1.00infobox
MAPK11Bgeevisual cortex1.00infobox
MAPK11Bgeeprimary visual cortex1.00infobox
MAPK11Bgeetail of embryo1.00infobox
MAPK11Bgeesuperior frontal gyrus1.00infobox
MAPK11Bgeesuperior cervical ganglion1.00infobox
MAPK11Bgeeganglionic eminence1.00infobox
MAPK11Bgeeprimary motor cortex1.00infobox
MAPK11Bgeecerebellar cortex1.00infobox
MAPK11BioGPSMore reference expression data1.00infobox
MAPK11Chr.Chromosome 22 (human)1.00infobox
MAPK11Chr.Chromosome 15 (mouse)1.00infobox
MAPK11DatabasesNCBI: entry; OMA: entry1.00infobox
MAPK11End50,270,767 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAPK11 bring nearby vocabulary together. In this analysis, examples include Protein, Mitogen-activated and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAPK11
    • Protein
    • Mitogen-activated
    • Gene
    • Activity
    • Function
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Map
  • mapk11
    • Protein
    • Mitogen-activated
    • Gene
    • Activity
    • Function
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Map
  • gene
    • Location
    • Chromosome
    • Human
    • Mapk11
    • Protein
    • Activity
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Search
  • map kinase
    • Kinases
    • Mapk11
    • Protein
    • Map
    • Mitogen-activated
    • Activated
    • Differentiation
    • P38
    • Phosphorylation
    • Proliferation
    • Regulation
    • Gene
  • transcription regulation
    • Cellular
    • Differentiation
    • Factor
    • Proliferation
    • Regulation
    • Transcription
    • Map
    • Search
    • Activity
    • Encoded
    • End
    • Function
  • p38 map kinase
    • Kinases
    • Mapk11
    • Protein
    • Map
    • Mitogen-activated
    • Activated
    • Differentiation
    • P38
    • Phosphorylation
    • Proliferation
    • Regulation
    • Gene
  • map kinase kinases
    • Kinases
    • Map
    • Mapk11
    • Protein
    • Mitogen-activated
    • Activated
    • Differentiation
    • P38
    • Phosphorylation
    • Proliferation
    • Regulation
    • Gene
  • transcription factor
    • Cellular
    • Differentiation
    • Factor
    • Proliferation
    • Regulation
    • Transcription
    • Function
    • Map
    • Mouse
    • Phosphorylation
    • Search
    • Shown

Connections between topic areas Semantic bridges

For MAPK11, one of the stronger structural bridges in this analysis connects MAPK11 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAPK11Function · splits 8 ⟂ 12
MAPK11Interactions · splits 16 ⟂ 4
MAPK11Overview · splits 17 ⟂ 3

Map overview Semantic statistics

MAPK11

Nodes20
Edges19
Triples101
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around MAPK11 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAPK11 · EN edition · Analysis: TopicsToTalkAbout

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