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DUSP1: Interactions & Overview

Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene.

Language: English [EN]
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DUSP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around DUSP1.

Related topics
6
Source areas
2
Connected nodes
8
Extracted relationships
121
Concept neighborhoods
4
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.3.16
3.1.3.48
Aliases
DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10, dual specificity phosphatase 1
Band
5q35.1 · 17 A3.3|17 13.28 cM
Bgee
vena cava · nipple · urethra · mucosa of paranasal sinus · skin of thigh
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DUSP1 connects Entity context

The extracted context around DUSP1 shows recurring relationship patterns in the source. For example, DUSP1 → cell cycle, cellular response to chemokine, cellular response to hormone stimulus, cytoplasm, dephosphorylation, endoderm formation, growth factor binding, hydrolase activity, intracellular signal transduction, MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase binding, negative regulation of apoptotic process, negative regulation of cell adhesion, negative regulation of cell population proliferation, negative regulation of DNA biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of MAPK cascade, negative regulation of meiotic cell cycle, negative regulation of monocyte chemotaxis Another extracted example is DUSP1 → ankle, ascending aorta, cardia, endothelial cell of lymphatic vessel, granulocyte, left lobe of liver, lower lobe of lung, mucosa of paranasal sinus, mucosa of urinary bladder, nipple, plantaris muscle, right lung, right lung lobe, saphenous vein, skin of thigh, soleus muscle, stroma of bone marrow, trachea, urethra, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.

DUSP1

Top relations

Gene ontology · 47
DUSP1 → cell cycle, cellular response to chemokine, cellular response to hormone stimulus, cytoplasm, dephosphorylation, endoderm formation, growth factor binding, hydrolase activity, intracellular signal transduction, MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase binding, negative regulation of apoptotic process, negative regulation of cell adhesion, negative regulation of cell population proliferation, negative regulation of DNA biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of MAPK cascade, negative regulation of meiotic cell cycle, negative regulation of monocyte chemotaxis
Bgee · 20
DUSP1 → ankle, ascending aorta, cardia, endothelial cell of lymphatic vessel, granulocyte, left lobe of liver, lower lobe of lung, mucosa of paranasal sinus, mucosa of urinary bladder, nipple, plantaris muscle, right lung, right lung lobe, saphenous vein, skin of thigh, soleus muscle, stroma of bone marrow, trachea, urethra, vena cava
RNA expression pattern · 20
DUSP1 → ankle, ascending aorta, cardia, endothelial cell of lymphatic vessel, granulocyte, left lobe of liver, lower lobe of lung, mucosa of paranasal sinus, mucosa of urinary bladder, nipple, plantaris muscle, right lung, right lung lobe, saphenous vein, skin of thigh, soleus muscle, stroma of bone marrow, trachea, urethra, vena cava
related to Function · 8
DUSP1 → Furthermore, H1, It, MAP, The, Thus, Tyr/Ser-protein, Xenopus
related to Interactions · 3
DUSP1 → MAPK1, MAPK14, MAPK8
Band · 2
DUSP1 → 17 A3.3|17 13.28 cM, 5q35.1
Chr. · 2
DUSP1 → Chromosome 17 (mouse), Chromosome 5 (human)
End · 2
DUSP1 → 172,771,195 bp, 26,781,102 bp
3.1.3.16 · 1
DUSP1 → ↗
3.1.3.48 · 1
DUSP1 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp gene chr band phosphatase chromosome protein location activity enzyme mouse map kinase stress dual specificity function encoded 771

DUSP1 relationships Subject–Predicate–Object triples

TTTA extracted 121 structured relationships around DUSP1. Examples in this analysis include DUSP1 → 3.1.3.16 → ↗ and DUSP1 → Aliases → DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10, dual specificity phosphatase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DUSP13.1.3.161.00infobox
DUSP13.1.3.481.00infobox
DUSP1AliasesDUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10, dual specificity phosphatase 11.00infobox
DUSP1Band5q35.11.00infobox
DUSP1Band17 A3.3|17 13.28 cM1.00infobox
DUSP1Bgeevena cava1.00infobox
DUSP1Bgeenipple1.00infobox
DUSP1Bgeeurethra1.00infobox
DUSP1Bgeemucosa of paranasal sinus1.00infobox
DUSP1Bgeeskin of thigh1.00infobox
DUSP1Bgeemucosa of urinary bladder1.00infobox
DUSP1Bgeecardia1.00infobox
DUSP1Bgeelower lobe of lung1.00infobox
DUSP1Bgeesaphenous vein1.00infobox
DUSP1Bgeetrachea1.00infobox
DUSP1Bgeegranulocyte1.00infobox
DUSP1Bgeestroma of bone marrow1.00infobox
DUSP1Bgeeendothelial cell of lymphatic vessel1.00infobox
DUSP1Bgeeright lung1.00infobox
DUSP1Bgeeright lung lobe1.00infobox
DUSP1Bgeeplantaris muscle1.00infobox
DUSP1Bgeeascending aorta1.00infobox
DUSP1Bgeesoleus muscle1.00infobox
DUSP1Bgeeankle1.00infobox
DUSP1Bgeeleft lobe of liver1.00infobox
DUSP1BioGPSMore reference expression data1.00infobox
DUSP1Chr.Chromosome 5 (human)1.00infobox
DUSP1Chr.Chromosome 17 (mouse)1.00infobox
DUSP1DatabasesNCBI: entry; OMA: entry1.00infobox
DUSP1End172,771,195 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DUSP1 bring nearby vocabulary together. In this analysis, examples include Phosphatase, Activity and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DUSP1
    • Phosphatase
    • Activity
    • Protein
    • Gene
    • Human
    • Dephosphorylation
    • Enzyme
    • Expressed
    • Function
    • Mitogen-activated
    • Negative
    • Regulation
  • dusp1
    • Phosphatase
    • Activity
    • Protein
    • Gene
    • Human
    • Dephosphorylation
    • Enzyme
    • Expressed
    • Function
    • Mitogen-activated
    • Negative
    • Regulation
  • gene
    • Phosphatase
    • Location
    • Chromosome
    • Protein
    • Bp
    • Chr
    • Human
    • A3
    • End
    • Function
    • Mouse
    • Specificity
  • enzyme
    • Specificity
    • Gene
    • Phosphatase
    • Dusp1
    • Encoded
    • Function
    • Activity
    • Location
    • Chromosome
    • Protein
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For DUSP1, one of the stronger structural bridges in this analysis connects DUSP1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DUSP1Interactions · splits 4 ⟂ 5
DUSP1Overview · splits 6 ⟂ 3

Map overview Semantic statistics

DUSP1

Nodes9
Edges8
Triples121
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around DUSP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DUSP1 · EN edition · Analysis: TopicsToTalkAbout

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