MAP3K10

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Explore the main themes, entities and connections around MAP3K10. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact CDC42 Huntingtin KIF3A MAPK8IP1

7 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

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2.7.11.25: ↗
Aliases: MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF0
Band: 19q13.2 · 7|7 A3
Bgee: right frontal lobe · prefrontal cortex · cingulate gyrus · anterior cingulate cortex · amygdala
BioGPS: More reference expression data

Topics to explore

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Overview

Interactions

Interact Protein-protein interaction
CDC42
Huntingtin
KIF3A
MAPK8IP1
MAPK8IP2
NEUROD1

Advanced semantic analysis

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Map overview Semantic statistics

Nodes12

Edges11

Triples99

Avg. degree1.83

Density0.166667

Components1

How this topic connects Entity context

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MAP3K10

Top relations

Gene ontology · 29

MAP3K10 → apoptotic process, ATP binding, bHLH transcription factor binding, cell death, cytoplasm, intracellular anatomical structure, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, negative regulation of DNA-binding transcription factor activity, negative regulation of transcription, DNA-templated, nucleotide binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, positive regulation of apoptotic process, positive regulation of JNK cascade, positive regulation of JUN kinase activity

Bgee · 20

MAP3K10 → amygdala, anterior cingulate cortex, ascending aorta, beta cell, Brodmann area 9, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, muscle of thigh, neural layer of retina, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, spermatocyte, superior frontal gyrus, ventricular zone

RNA expression pattern · 20

related to Interactions · 5

MAP3K10 → CDC42, Huntingtin, KIF3A, MAPK8IP1, MAPK8IP2

Band · 2

MAP3K10 → 19q13.2, 7|7 A3

Chr. · 2

MAP3K10 → Chromosome 19 (human), Chromosome 7 (mouse)

End · 2

MAP3K10 → 27,374,023 bp, 40,215,575 bp

2.7.11.25 · 1

MAP3K10 → ↗

Aliases · 1

MAP3K10 → MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10

Available structures · 1

MAP3K10 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF0

Important terminology Word statistics

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Important terminology

bp kinase gene chr human band protein chromosome 19 location enzyme mouse jnk mitogen-activated 10 function encoded search activity 215

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
MAP3K10	2.7.11.25	↗	1.00	infobox
MAP3K10	Aliases	MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10	1.00	infobox
MAP3K10	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF0	1.00	infobox
MAP3K10	Band	19q13.2	1.00	infobox
MAP3K10	Band	7\|7 A3	1.00	infobox
MAP3K10	Bgee	right frontal lobe	1.00	infobox
MAP3K10	Bgee	prefrontal cortex	1.00	infobox
MAP3K10	Bgee	cingulate gyrus	1.00	infobox
MAP3K10	Bgee	anterior cingulate cortex	1.00	infobox
MAP3K10	Bgee	amygdala	1.00	infobox
MAP3K10	Bgee	beta cell	1.00	infobox
MAP3K10	Bgee	nucleus accumbens	1.00	infobox
MAP3K10	Bgee	putamen	1.00	infobox
MAP3K10	Bgee	Brodmann area 9	1.00	infobox
MAP3K10	Bgee	right hemisphere of cerebellum	1.00	infobox
MAP3K10	Bgee	superior frontal gyrus	1.00	infobox
MAP3K10	Bgee	primary visual cortex	1.00	infobox
MAP3K10	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
MAP3K10	Bgee	muscle of thigh	1.00	infobox
MAP3K10	Bgee	ventricular zone	1.00	infobox
MAP3K10	Bgee	neural layer of retina	1.00	infobox
MAP3K10	Bgee	cerebellar cortex	1.00	infobox
MAP3K10	Bgee	spermatocyte	1.00	infobox
MAP3K10	Bgee	ganglionic eminence	1.00	infobox
MAP3K10	Bgee	ascending aorta	1.00	infobox
MAP3K10	BioGPS	More reference expression data	1.00	infobox
MAP3K10	Chr.	Chromosome 19 (human)	1.00	infobox
MAP3K10	Chr.	Chromosome 7 (mouse)	1.00	infobox
MAP3K10	Databases	NCBI: entry; OMA: entry	1.00	infobox
MAP3K10	End	40,215,575 bp	1.00	infobox

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