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MAP3K10: Interactions & Overview

Mitogen-activated protein kinase kinase kinase 10 is an enzyme that in humans is encoded by the MAP3K10 gene.

Language: English [EN]
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MAP3K10 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around MAP3K10.

Related topics
9
Source areas
2
Connected nodes
11
Extracted relationships
99
Concept neighborhoods
5
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.25
Aliases
MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF0
Band
19q13.2 · 7|7 A3
Bgee
right frontal lobe · prefrontal cortex · cingulate gyrus · anterior cingulate cortex · amygdala
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAP3K10 connects Entity context

The extracted context around MAP3K10 shows recurring relationship patterns in the source. For example, MAP3K10 → apoptotic process, ATP binding, bHLH transcription factor binding, cell death, cytoplasm, intracellular anatomical structure, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, negative regulation of DNA-binding transcription factor activity, negative regulation of transcription, DNA-templated, nucleotide binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, positive regulation of apoptotic process, positive regulation of JNK cascade, positive regulation of JUN kinase activity Another extracted example is MAP3K10 → amygdala, anterior cingulate cortex, ascending aorta, beta cell, Brodmann area 9, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, muscle of thigh, neural layer of retina, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, spermatocyte, superior frontal gyrus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAP3K10

Top relations

Gene ontology · 29
MAP3K10 → apoptotic process, ATP binding, bHLH transcription factor binding, cell death, cytoplasm, intracellular anatomical structure, JNK cascade, JUN kinase kinase kinase activity, kinase activity, MAP kinase kinase kinase activity, MAPK cascade, negative regulation of DNA-binding transcription factor activity, negative regulation of transcription, DNA-templated, nucleotide binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, positive regulation of apoptotic process, positive regulation of JNK cascade, positive regulation of JUN kinase activity
Bgee · 20
MAP3K10 → amygdala, anterior cingulate cortex, ascending aorta, beta cell, Brodmann area 9, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, muscle of thigh, neural layer of retina, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, spermatocyte, superior frontal gyrus, ventricular zone
RNA expression pattern · 20
MAP3K10 → amygdala, anterior cingulate cortex, ascending aorta, beta cell, Brodmann area 9, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, muscle of thigh, neural layer of retina, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, spermatocyte, superior frontal gyrus, ventricular zone
related to Interactions · 5
MAP3K10 → CDC42, Huntingtin, KIF3A, MAPK8IP1, MAPK8IP2
Band · 2
MAP3K10 → 19q13.2, 7|7 A3
Chr. · 2
MAP3K10 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
MAP3K10 → 27,374,023 bp, 40,215,575 bp
2.7.11.25 · 1
MAP3K10 → ↗
Aliases · 1
MAP3K10 → MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10
Available structures · 1
MAP3K10 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF0

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp kinase gene chr human band protein chromosome 19 location enzyme mouse jnk mitogen-activated 10 function encoded search activity 215

MAP3K10 relationships Subject–Predicate–Object triples

TTTA extracted 99 structured relationships around MAP3K10. Examples in this analysis include MAP3K10 → 2.7.11.25 → ↗ and MAP3K10 → Aliases → MAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAP3K102.7.11.251.00infobox
MAP3K10AliasesMAP3K10, MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 101.00infobox
MAP3K10Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RF01.00infobox
MAP3K10Band19q13.21.00infobox
MAP3K10Band7|7 A31.00infobox
MAP3K10Bgeeright frontal lobe1.00infobox
MAP3K10Bgeeprefrontal cortex1.00infobox
MAP3K10Bgeecingulate gyrus1.00infobox
MAP3K10Bgeeanterior cingulate cortex1.00infobox
MAP3K10Bgeeamygdala1.00infobox
MAP3K10Bgeebeta cell1.00infobox
MAP3K10Bgeenucleus accumbens1.00infobox
MAP3K10Bgeeputamen1.00infobox
MAP3K10BgeeBrodmann area 91.00infobox
MAP3K10Bgeeright hemisphere of cerebellum1.00infobox
MAP3K10Bgeesuperior frontal gyrus1.00infobox
MAP3K10Bgeeprimary visual cortex1.00infobox
MAP3K10Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
MAP3K10Bgeemuscle of thigh1.00infobox
MAP3K10Bgeeventricular zone1.00infobox
MAP3K10Bgeeneural layer of retina1.00infobox
MAP3K10Bgeecerebellar cortex1.00infobox
MAP3K10Bgeespermatocyte1.00infobox
MAP3K10Bgeeganglionic eminence1.00infobox
MAP3K10Bgeeascending aorta1.00infobox
MAP3K10BioGPSMore reference expression data1.00infobox
MAP3K10Chr.Chromosome 19 (human)1.00infobox
MAP3K10Chr.Chromosome 7 (mouse)1.00infobox
MAP3K10DatabasesNCBI: entry; OMA: entry1.00infobox
MAP3K10End40,215,575 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAP3K10 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAP3K10
    • Protein
    • Gene
    • Activity
    • Function
    • Mitogen-activated
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
  • map3k10
    • Protein
    • Gene
    • Activity
    • Function
    • Mitogen-activated
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Map3k10
    • Activity
    • Bp
    • Chr
    • End
    • Function
    • Kinase
    • Mitogen-activated
  • enzyme
    • Mitogen-activated
    • Protein
    • Gene
    • Humans
    • Interactions
    • Map3k10
    • Reading
    • References
    • Kinase
    • Activity
    • Encoded
    • Function
  • interactions
    • Reading
    • References
    • Mitogen-activated
    • Search
    • Location
    • Protein
    • Human
    • Map3k10
    • Kinase

Connections between topic areas Semantic bridges

For MAP3K10, one of the stronger structural bridges in this analysis connects MAP3K10 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAP3K10Interactions · splits 4 ⟂ 8
MAP3K10Overview · splits 9 ⟂ 3

Map overview Semantic statistics

MAP3K10

Nodes12
Edges11
Triples99
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around MAP3K10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAP3K10 · EN edition · Analysis: TopicsToTalkAbout

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